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254444000 668038000 -17640000 650398000 5985000 5985000 -1417000 4568000 469000 469000 469000 469000 5985000 6454000 -1417000 5037000 514406 9000 1016000 1025000 11000 1036000 -684000 -684000 -684000 7805000 7805000 2822000 10627000 -12888000 -12888000 -12888000 13000 13000 285885025 5417000 288978000 138506000 469000 -24050000 260429000 669748000 -16210000 653539000 4568000 366065000 -70659000 6645000 6665000 2778000 0 0 30000 0 42938000 0 10718000 14468000 12637000 -232674000 37863000 20307000 54976000 0 0 0 0 -843000 0 264409000 41730000 0 -445582000 -10287000 0 0 349000 66000 140000 161000 34117000 -30791000 11491000 14402000 112077000 1723000 0 0 -271000 6114000 46229000 -8446000 -529000 747000 467000 0 -48000 -1327000 -3371000 -25000 774000 -5223000 186000 4841000 605000 11166000 5094000 -7000 3002000 115000 20737000 0 0 1155000 3648000 0 2651000 2495000 0 -131827000 -98156000 -72796000 5170000 12138000 4365000 0 0 125000 254000 400000 125000 10000000 13670000 3500000 1150000 1556000 0 350586000 9294000 0 350000 191000 0 0 6480000 0 0 -16036000 -13390000 0 69541000 166452000 30116000 173995000 148062000 364478000 63659000 -39645000 68000 0 0 14720000 0 0 25000000 1606000 6147000 2908000 1678000 0 0 178000 185000 0 112000 0 1036000 504000 0 0 0 152030000 -12888000 0 0 0 1280000 0 13750000 51048000 0 -92000 0 0 0 0 35000 0 0 1062000 0 0 8000 38869000 49910000 156887000 0 -104000 -44000 271520000 15309000 44402000 132360000 117051000 72649000 403881000 132360000 117051000 0 9106000 0 0 15894000 0 0 10680000 0 0 4894000 0 0 2418000 0 20737000 176000 92000 Accounting policies<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Description of Business</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Health plc (“PureTech,” the “Parent” or the “Company”) is a public company incorporated, domiciled and registered in the United Kingdom (“UK”). The registered number is 09582467 and the registered address is 8th Floor, 20 Farringdon Street, London EC4A 3AE, United Kingdom.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech’s group financial statements consolidate those of the Company and its subsidiaries (together referred to as the “Group”). The Parent company financial statements present financial information about the Company as a separate entity and not about its Group.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The accounting policies set out below have, unless otherwise stated, been applied consistently to all periods presented in these group financial statements.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Basis of Presentation</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The consolidated financial statements of the Group are presented as of December 31, 2020 and 2019 and for the years ended December 31, 2020, 2019 and 2018. The Group financial statements have been approved by the Directors on April 14, 2021 and are prepared in accordance with international accounting standards in conformity with the requirements of the Companies Act 2006 and International Financial Reporting Standards (IFRSs) adopted pursuant to Regulation (EC) No 1606/2002 as it applies in the EU. The Consolidated Financial Statements also comply fully with IFRSs as issued by the International Accounting Standards Board (IASB). IFRSs as adopted pursuant to Regulation (EC) No 1606/2002 as it applies in the EU differs in certain respects from IFRS as issued by the IASB. However, the differences have no impact for the periods presented.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For presentation of the Consolidated Statements of Comprehensive Income/(Loss), the Company uses a classification based on the function of expenses, rather than based on their nature, as it is more representative of the format used for internal reporting and management purposes and is consistent with international practice.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Certain amounts in the Consolidated Financial Statements and accompanying notes may not add due to rounding. All percentages have been calculated using unrounded amounts.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Basis of Measurement </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The consolidated financial statements are prepared on the historical cost basis except that the following assets and liabilities are stated at their fair value: investments held at fair value and liabilities classified as fair value through the profit or loss. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Use of Judgments and Estimates </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In preparing these consolidated financial statements, management has made judgements, estimates and assumptions that affect the application of the Group’s accounting policies and the reported amounts of assets, liabilities, income and expenses. Actual results may differ from these estimates. Estimates and underlying assumptions are reviewed on an on-going basis.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Significant estimation applied in determining the following:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Financial instruments valuations (Note 16): when estimating the fair value of subsidiary convertible notes and subsidiary preferred shares carried at fair value through profit and loss (FVTPL) and investments held at fair value, at initial recognition and upon subsequent measurement. This includes determining the appropriate valuation methodology and making certain estimates of the future earnings potential of the subsidiary businesses, appropriate discount rate and earnings multiple to be applied, marketability and other industry and company specific risk factors. See Note 16 for the sensitivity analysis for key estimates used in these valuations.</span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Valuation of share based payments (Note 8): when estimating the fair value of share based payment on grant date. This includes making certain estimates regarding the expected life of the share-based award, share price volatility, risk free interest rate as well as other covariance of comparable public companies and other market data to predict distribution of relative share performance.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Significant judgement is also applied in determining the following:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Revenue recognition (Note 3): when determining the correct amount of revenue to be recognized. This includes making certain judgements when determining the appropriate accounting treatment of key customer contract terms in accordance with the applicable accounting standards. In particular, judgement is required to determine the performance obligations in a contract (if promised goods and services are distinct or not) and timing of revenue recognition (on delivery or over a period of time).</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Subsidiary preferred shares liability classification (Note 15): when determining the classification of financial instruments in terms of liability or equity. These judgements include an assessment of whether the financial instrument include any embedded derivative features, whether they include contractual obligations upon the Group to deliver cash or other financial assets or to exchange financial assets or financial liabilities with another party, and whether that obligation will be settled by the Company exchanging a fixed amount of cash or other financial assets for a fixed number of its own equity instruments. Further information about these critical judgements and estimates is included below under Financial Instruments.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">When the power to control the subsidiaries exists (please refer to Notes 5 and 6 and accounting policy below Subsidiaries). This judgement includes an assessment of whether the Company has (i) power over the investee; (ii) exposure, or rights, to variable returns from its involvement with the investee; and (iii) the ability to use its power over the investee to affect the amount of the investor’s returns. The Company considers among others its voting shares, representation on the board, rights to appoint management, investee dependence on the Company etc. If the power to control investees exists we consolidate the financial statements of such investee in the consolidated financial statements of the Group. Upon issuance of new shares in a subsidiary </span></div><div style="padding-left:11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">and a resulting change in any shareholders or governance agreements, the Group reassesses its ability to control the investee based on the revised board composition and revised subsidiary governance and management structure. When such new circumstances result in the Group losing its power to control the investee, the investee is deconsolidated.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Whether the Company has significant influence over financial and operating policies of investees in order to determine if the Company should account for its investment as an associate based on IAS 28 or based on IFRS 9, Financial Instruments (please refer to Note 5). This judgement includes, among others, an assessment whether the Company has representation on the board of directors of the investee, whether the Company participates in the policy making processes of the investee, whether there is any interchange of managerial personnel, whether there is any essential technical information provided to the investee and if there are any transactions between the Company and the investee.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Upon determining that the Company does have significant influence over the financial and operating policies of an investee, if the Company holds more than a single instrument issued by its equity-accounted investee, judgement is required to determine whether the additional instrument forms part of the investment in the associate, which is accounted for under IAS 28 and scoped out of IFRS 9, or it is a separate financial instrument that falls in the scope of IFRS 9 (please refer to Notes 5 and 6). This judgement includes an assessment of the characteristics of the financial instrument of the investee held by the Company and whether such financial instrument provides access to returns underlying an ownership interest.</span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Where the company has other investments in an equity accounted investee that are not accounted for under IAS 28, judgement is required in determining if such investments constitute Long-Term Interests for the purposes of IAS 28 (please refer to Notes 5 and 6). This determination is based on the individual facts and circumstances and characteristics of each investment, but is driven, among other factors, by the intention and likelihood to settle the instrument through redemption or repayment in the foreseeable future, and whether or not the investment is likely to be converted to common stock or other equity instruments (please also refer to accounting policy with regard to Investments in Associates below). When considering the individual facts and circumstances of the Group’s investment in its associate's preferred stock in the manner described above, including the long-term nature of such investment, the ability of the Group to convert its preferred stock investment to an investment in common shares and the likelihood of such conversion, as well the fact that there is no planned redemption or other settlement of the preferred stock by the investee in the foreseeable future, we concluded that such investment is considered a Long Term Interest.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of December 31, 2020 the Group had cash and cash equivalents of $403.9 million. Considering the Group’s and the Company's financial position as of December 31, 2020 and its principal risks and opportunities, a going concern analysis has been prepared for at least the twelve-month period from the date of signing the Consolidated Financial Statements ("the going concern period") utilizing realistic scenarios and applying a severe but plausible downside scenario. Even under the downside scenario, the analysis demonstrates the Group and the Company continue to maintain sufficient liquidity headroom and continues to comply with all financial obligations. On February 9, 2021, the Group sold 1,000,000 common shares of Karuna for aggregate proceeds of $118.0 million, further strengthening the liquidity headroom of the Group. Therefore, the Directors believe the Group and the Company is adequately resourced to continue in operational existence for at least the twelve-month period from the date of signing the Consolidated Financial Statements, irrespective of uncertainty regarding the duration and severity of the COVID-19 pandemic and the global macroeconomic impact of the pandemic. Accordingly, the Directors considered it appropriate to adopt the going concern basis of accounting in preparing the Consolidated Financial Statements and the PureTech Health plc Financial Statements. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Basis of consolidation</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The consolidated financial information as of December 31, 2020 and 2019 and for each of the years ended December 31, 2020, 2019 and 2018 comprises an aggregation of financial information of the Company and the consolidated financial information of PureTech Health LLC (“PureTech LLC”). Intra-group balances and transactions, and any unrealized income and expenses arising from intra-group transactions, are eliminated.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiaries </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As used in these financial statements, the term subsidiaries refers to entities that are controlled by the Group. Financial results of subsidiaries of the Group as of December 31, 2020 are reported within the Internal segment, Controlled Founded Entities segment or the Parent Company and Other segment (please refer to Note 4). Under applicable accounting rules, the Group controls an entity when it is exposed to, or has the rights to, variable returns from its involvement with the entity and has the ability to affect those returns through its power over the entity. In assessing control, the Group takes into consideration potential voting rights and board interest and holding. The financial statements of subsidiaries are included in the consolidated financial statements from the date that control commences until the date that control ceases. Losses applicable to the non-controlling interests in a subsidiary are allocated to the non-controlling interests even if doing so causes the non-controlling interests to have a deficit balance.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">A list of all current and former subsidiaries organized with respect to classification as of December 31, 2020 and the Group’s total voting percentage, based on outstanding voting common and preferred shares as of December 31, 2020, 2019 and 2018, is outlined below. All current subsidiaries are domiciled within the United States and conduct business activities solely within the United States. </span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:41.668%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.233%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="24" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Voting percentage at December 31, through the holdings in</span></div></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="6" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="6" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Subsidiary</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Common</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"><span style="font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%"> Preferred</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Common</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"><span style="font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%"> Preferred</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Common</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"><span style="font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%"> Preferred</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Subsidiary operating companies</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Alivio Therapeutics, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">91.9</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">91.9 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">92.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega, Inc. (indirectly held through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">83.1</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">83.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">83.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica, Incorporated</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2,5</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">28.7</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">56.7</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">56.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4.4 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">79.2 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:41.668%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.233%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech LYT (formerly Ariya Therapeutics, Inc.)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">8</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech LYT-100</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Management, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">3</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Health LLC</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">3</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde Health, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">51.8</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">64.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">96.4 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta Biosciences, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">59.3</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">61.8 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">74.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta Biosciences Securities Corp. (indirectly held through Vedanta)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">59.3</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">61.8 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">74.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Deconsolidated former subsidiary operating companies</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Akili Interactive Labs, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2,7</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">41.9</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41.9 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41.9 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2,9</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4.9</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">20.2</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">20.2 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">18.4 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Karuna Pharmaceuticals, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2,10</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">12.6</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.4 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">71.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vor Biopharma Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2,11</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">16.4</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">47.5 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">93.2 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Nontrading holding companies</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:justify"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.4pt;font-weight:400;line-height:120%">Endra Holdings, LLC (held indirectly through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.46pt;font-weight:400;line-height:120%;position:relative;top:-2.94pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:justify"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.4pt;font-weight:400;line-height:120%">Ensof Holdings, LLC (held indirectly through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.46pt;font-weight:400;line-height:120%;position:relative;top:-2.94pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Securities Corp.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Securities II Corp.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Inactive subsidiaries</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Appeering, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Commense Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2,6</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">99.1</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">99.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">99.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Enlight Biosciences, LLC</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8pt;font-weight:400;line-height:120%">Ensof Biosystems, Inc. (held indirectly through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.2pt;font-weight:400;line-height:120%;position:relative;top:-2.8pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">57.7</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">28.3</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">57.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">57.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Knode Inc. (indirectly held through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Libra Biosciences, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Mandara Sciences, LLC</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">98.3</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">98.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">98.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tal Medical, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">64.5 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    The voting percentage is impacted by preferred shares that are classified as liabilities, which results in the ownership percentage not being the same as the ownership percentage used in allocations to non-controlling interests disclosed in Note 18. The allocation of losses/profits to the noncontrolling interest is based on the holdings of subordinated stock that provide ownership rights in the subsidiaries. The ownership of liability classified preferred shares are quantified in Note 15.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Registered address is Corporation Trust Center, 1209 Orange St., Wilmington, DE 19801, USA.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">3    Registered address is 2711 Centerville Rd., Suite 400, Wilmington, DE 19808, USA.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">4    The Company’s interests in its subsidiaries are predominantly in the form of preferred shares, which have a liquidation preference over the common stock, are convertible into common stock at the holder’s discretion or upon certain liquidity events, are entitled to one vote per share on all matters submitted to shareholders for a vote and entitled to receive dividends when and if declared. In the case of Enlight, Mandara and PureTech Health LLC, the holdings are membership interests in an LLC. The holders of common stock are entitled to one vote per share on all matters submitted to shareholders for a vote and entitled to receive dividends when and if declared.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">5    On July 19, 2019, all of the outstanding notes, plus accrued interest, issued by Follica to PureTech converted into 15,216,214 shares of Series A-3 Preferred Shares and 12,777,287 shares of common share pursuant to a Series A-3 Note Conversion Agreement between Follica and the noteholders. Please refer to Note 16.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">6    Commense turned inactive during 2019.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">7    On May 8, 2018, PureTech lost control of Akili, Akili was deconsolidated from the Group’s financial statements and is no longer considered a subsidiary. This results in only the profits and losses generated by Akili through the deconsolidation date being included in the Group’s Consolidated Statement of Income/(Loss) and Other Comprehensive Income/(Loss). See Note 5 for further details about the accounting for the investment in Akili subsequent to deconsolidation.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">8    On July 18, 2018, Calix Biopharma, Inc., Glyph Biosciences, Inc., and Nybo Therapeutics, Inc. merged into Ariya Therapeutics, Inc. Thus, the Group no longer holds an interest in Calix, Glyph and Nybo but rather owns 100.0 percent voting interest of Ariya.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">9    As of December 31, 2018, PureTech maintained control of Gelesis. On July 1, 2019 PureTech lost control of Gelesis and Gelesis was deconsolidated from the Group’s financial statements, resulting in only the profits and losses generated by Gelesis through the deconsolidation date being included in the Group’s Consolidated Statement of Income/(Loss) and Other Comprehensive Income/(Loss). See Notes 5 and 6 for further details about the accounting for the investments in Gelesis subsequent to deconsolidation.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">10    On March 15, 2019, PureTech lost control of Karuna, Karuna was deconsolidated from the Group’s financial statements and is no longer considered a subsidiary. This results in only the profits and losses generated by Karuna through the deconsolidation date being included in the Group’s Consolidated Statement of Income/(Loss) and Other Comprehensive Income/(Loss). See Note 5 for further details about the accounting for the investment in Karuna subsequent to deconsolidation.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">11    On February 12, 2019, PureTech lost control of Vor, Vor was deconsolidated from the Group’s financial statements and is no longer considered a subsidiary. This results in only the profits and losses generated by Vor through the deconsolidation date being included in the Group’s Consolidated Statement of Income/(Loss) and Other Comprehensive Income/(Loss).See Note 5 for further details about the accounting for the investment in Vor subsequent to deconsolidation.</span></div><div style="margin-bottom:5.25pt"><span><br/></span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in subsidiary ownership and loss of control </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Changes in the Group’s interest in a subsidiary that do not result in a loss of control are accounted for as equity transactions.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Where the Group loses control of a subsidiary, the assets and liabilities are derecognized along with any related non-controlling interest (“NCI”). Any interest retained in the former subsidiary is measured at fair value when control is lost. Any resulting gain or loss is recognized as profit or loss in the Consolidated Statements of Comprehensive Income/(Loss).</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Associates </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As used in these financial statements, the term associates are those entities in which the Group has no control but maintains significant influence over the financial and operating policies. Significant influence is presumed to exist when the Group holds between 20 and 50 percent of the voting power of an entity, unless it can be clearly demonstrated that this is not the case. The Group evaluates if it maintains significant influence over associates by assessing if the Group has lost the power to participate in the financial and operating policy decisions of the associate.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Application of the equity method to associates </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Associates are accounted for using the equity method (equity accounted investees) and are initially recognized at cost, or if recognized upon deconsolidation they are initially recorded at fair value at the date of deconsolidation. The consolidated financial statements include the Group’s share of the total comprehensive income and equity movements of equity accounted investees, from the date that significant influence commences until the date that significant influence ceases. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">To the extent the Group holds interests in associates that are not providing access to returns underlying ownership interests, the instrument held by PureTech is accounted for in accordance with IFRS 9 as investments held at fair value.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">When the Group’s share of losses exceeds its equity method investment in the investee, losses are applied against Long-Term Interests, which are investments accounted for under IFRS 9. Investments are determined to be Long-Term Interests when they are long-term in nature and in substance they form part of the Group's net investment in that associate. This determination is impacted by many factors, among others, whether settlement by the investee through redemption or repayment is planned or likely in the foreseeable future, whether the investment can be converted and/or is likely to be converted to common stock or other equity instrument and other factors regarding the nature of the investment. Whilst this assessment is dependent on many specific facts and circumstances of each investment, typically conversion features whereby the investment is likely to convert to common stock or other equity instruments would point to the investment being a Long-Term Interest. Similarly, where the investment is not planned or likely to be settled through redemption or repayment in the foreseeable future, this would indicate that the investment is a Long-Term Interest. When the net investment in the associate, which includes the Group’s investments in other long-term interests, is reduced to nil, recognition of further losses is discontinued except to the extent that the Group has incurred legal or constructive obligations or made payments on behalf of an investee.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group has also adopted the amendments to IAS 28 Investments in Associates that addresses the dual application of IAS 28 and IFRS 9 (see below) when equity method losses are applied against Long-Term Interests (LTI). The amendments provide the annual sequence in which both standards are to be applied in such a case. The Group has applied the equity method losses to the LTIs presented as part of Investments held at fair value subsequent to remeasuring such investments to their fair value at balance sheet date.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in Accounting Policy </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of January 1, 2019, the Group has adopted new accounting policies for the accounting for leases. See updated accounting policy for leases (IFRS 16) below.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial Instruments </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Classification </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group classifies its financial assets in the following measurement categories:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Those to be measured subsequently at fair value (either through other comprehensive income, or through profit or loss), and</span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Those to be measured at amortized cost.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The classification depends on the Group’s business model for managing the financial assets and the contractual terms of the cash flows.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For assets measured at fair value, gains and losses will are recorded in profit or loss. For investments in debt instruments, this will depend on the business model in which the investment is held. For investments in equity instruments that are not held for trading, this will depend on whether the Group has made an irrevocable election at the time of initial recognition to account for the equity investment at FVOCI. As of balance sheet dates, none of the Company's financial assets are accounted for as FVOCI.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Measurement </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">At initial recognition, the Group measures a financial asset at its fair value plus, in the case of a financial asset not at FVTPL, transaction costs that are directly attributable to the acquisition of the financial asset. Transaction costs of financial assets that are carried at FVTPL are expensed.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group assesses on a forward-looking basis the expected credit losses associated with its debt instruments carried at amortized cost. The Group had no debt instruments carried at amortized cost as of balance sheet date. For trade receivables, the Group applies the simplified approach permitted by IFRS 9, which requires expected lifetime losses to be recognized from initial recognition of the receivables.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial Assets </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s financial assets consist of cash and cash equivalents, trade and other receivables, debt and equity securities, other deposits and investments in associates’ preferred shares. The Group’s financial assets are classified into the following categories: investments held at fair value, trade and other receivables, short-term investments and cash and cash equivalents. The Group determines the classification of financial assets at initial recognition depending on the purpose for which the financial assets were acquired.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investments held at fair value are investments in equity instruments that are not held for trading. Such investments consist of the Group's minority interest holdings where the Group has no significant influence or preferred share investments in the Group's associates that are not providing access to returns underlying ownership interests. These financial assets are initially measured at fair value and subsequently re-measured at fair value at each reporting date. The Company elects if the gain or loss will be recognized in Other Comprehensive Income/(Loss) or through profit and loss on an instrument by instrument basis. The Company has elected to record the changes in fair values for the financial assets falling under this category through profit and loss. Please refer to Note 5.</span></div><div style="margin-bottom:5.25pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term investments are short-term government treasury bonds carried at fair value with changes in fair value recorded through profit and loss in financing income.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Changes in the fair value of financial assets at FVTPL are recognized in other income/(expense) in the Consolidated Statements of Comprehensive Income/(Loss) as applicable. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other receivables are non-derivative financial assets with fixed and determinable payments that are not quoted on active markets. These financial assets are carried at the amounts expected to be received less any expected lifetime losses. Such losses are determined taking into account previous experience, credit rating and economic stability of counterparty and economic conditions. When a trade receivable is determined to be uncollectible, it is written off against the available provision. Trade and other receivables are included in current assets, unless maturities are greater than 12 months after the end of the reporting period.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial Liabilities </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s financial liabilities consist of trade and other payables, subsidiary notes payable, preferred shares, and warrant liability. Warrant liabilities are initially recognized at fair value. After initial recognition, these financial liabilities are re-measured at FVTPL using an appropriate valuation technique. Subsidiary notes payable without embedded derivatives are accounted for at amortized cost.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The majority of the Group’s subsidiaries have preferred shares and notes payable with embedded derivatives, which are classified as current liabilities. When the Group has preferred shares and notes with embedded derivatives that qualify for bifurcation, the Group has elected to account for the entire instrument as FVTPL after determining under IFRS 9 that the instrument qualifies to be accounted for under such FVTPL method.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group derecognizes a financial liability when its contractual obligations are discharged, cancelled or expire.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Equity Instruments Issued by the Group </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial instruments issued by the Group are treated as equity only to the extent that they meet the following two conditions, in accordance with IAS 32:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:4.26pt">They include no contractual obligations upon the Group to deliver cash or other financial assets or to exchange financial assets or financial liabilities with another party under conditions that are potentially unfavorable to the Group; and</span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:4.26pt">Where the instrument will or may be settled in the Group’s own equity instruments, it is either a non-derivative that includes no obligation to deliver a variable number of the Group’s own equity instruments or is a derivative that will be settled by the Group exchanging a fixed amount of cash or other financial assets for a fixed number of its own equity instruments.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">To the extent that this definition is not met, the financial instrument is classified as a financial liability. Where the instrument so classified takes the legal form of the Group’s own shares, the amounts presented in the financial information for share capital and merger reserve account exclude amounts in relation to those shares.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Changes in the fair value of liabilities at FVTPL are recognized in Net finance income (costs) in the Consolidated Statements of Comprehensive Income/(Loss) as applicable. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">IFRS 15, Revenue from Contracts with Customers </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The standard establishes a five-step principle-based approach for revenue recognition and is based on the concept of recognizing an amount that reflects the consideration for performance obligations only when they are satisfied and the control of goods or services is transferred.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The majority of the Group’s contract revenue is generated from licenses and services, some of which are part of collaboration arrangements. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Management reviewed contracts where the Group received consideration in order to determine whether or not they should be accounted for in accordance with IFRS 15. To date, PureTech has entered into transactions that generate revenue and meet the scope of either IFRS 15 or IAS 20 Accounting for Government Grants. Contract revenue is recognized at either a point-in-time or over time, depending on the nature of the services and existence of acceptance clauses.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group accounts for agreements that meet the definition of IFRS 15 by applying the following five step model:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Identify the contract(s) with a customer – A contract with a customer exists when (i) the Group enters into an enforceable contract with a customer that defines each party’s rights regarding the goods or services to be transferred and identifies the payment terms related to those goods or services, (ii) the contract has commercial substance and, (iii) the Group determines that collection of substantially all consideration for goods or services that are transferred is probable based on the customer’s intent and ability to pay the promised consideration.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Identify the performance obligations in the contract – Performance obligations promised in a contract are identified based on the goods or services that will be transferred to the customer that are both capable of being distinct, whereby the customer can benefit from the good or service either on its own or together with other resources that are readily available from third parties or from the Group, and are distinct in the context of the contract, whereby the transfer of the goods or services is separately identifiable from other promises in the contract.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Determine the transaction price – The transaction price is determined based on the consideration to which the Group will be entitled in exchange for transferring goods or services to the customer. To the extent the transaction price includes variable consideration, the Group estimates the amount of variable consideration that should be included in the transaction price utilizing either the expected value method or the most likely amount method depending on the nature of the variable consideration. Variable consideration is included in the transaction price if, in the Group’s judgement, it is probable that a significant future reversal of cumulative revenue under the contract will not occur. </span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Allocate the transaction price to the performance obligations in the contract – If the contract contains a single performance obligation, the entire transaction price is allocated to the single performance obligation. Contracts that contain multiple performance obligations require an allocation of the transaction price to each performance obligation based on a relative standalone selling price basis. </span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Recognize revenue when (or as) the Group satisfies a performance obligation – The Group satisfies performance obligations either over time or at a point in time as discussed in further detail below. Revenue is recognized at the time the related performance obligation is satisfied by transferring a promised good or service to a customer.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Revenue generated from services agreements (typically where licenses and related services were combined into one performance obligation) is determined to be recognized over time when it can be determined that the services meet one of the following: (a) the customer simultaneously receives and consumes the benefits provided by the entity’s performance as the entity performs; (b) the entity’s performance creates or enhances an asset that the customer controls as the asset is created or enhanced; or (c) the entity’s performance does not create an asset with an alternative use to the entity and the entity has an enforceable right to payment for performance completed to date.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">It was determined that the Group has contracts that meet criteria (a), since the customer simultaneously receives and consumes the benefits provided by the Company’s performance as the Company performs. Therefore revenue is recognized over time using the input method based on costs incurred to date as compared to total contract costs. The Company believes that in research and development service type agreements using costs incurred to date represents the most faithful depiction of the entity’s performance towards complete satisfaction of a performance obligation.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Revenue from licenses that are not part of a combined performance obligation are recognized at a point in time due to the licenses relating to intellectual property that has significant stand-alone functionality and as such represent a right to use the entity's intellectual property as it exists at the point in time at which the license is granted.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amounts that are receivable or have been received per contractual terms but have not been recognized as revenue since performance has not yet occurred or has not yet been completed are recorded as deferred revenue. The Company classifies as non-current deferred revenue amounts received for which performance is expected to occur beyond one year or one operating cycle.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant Income </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company recognizes grants from governmental agencies as grant income in the Consolidated Statement of Comprehensive Income/(Loss), gross of the expenditures that were related to obtaining the grant, when there is reasonable assurance that the Company will comply with the conditions within the grant agreement and there is reasonable assurance that payments under the grants will be received. The Company evaluates the conditions of each grant as of each reporting date to ensure that the Company has reasonable assurance of meeting the conditions of each grant arrangement and it is expected that the grant payment will be received as a result of meeting the necessary conditions.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company submits qualifying expenses for reimbursement after the Company has incurred the research and development expense. The Company records an unbilled receivable upon incurring such expenses. In cases were grant income is received prior to the expenses being incurred or recognized, the amounts received are deferred until the related expense is incurred and/or recognized. Grant income is recognized in the Consolidated Statements of Comprehensive Income/(Loss) over the periods in which the Company recognizes the related reimbursable expense for which the grant is intended to compensate.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Functional and Presentation Currency </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">These consolidated financial statements are presented in United States dollars (“US dollars”). The functional currency of virtually all members of the Group is the U.S. dollar. The assets and liabilities of a previously held subsidiary were translated to U.S. dollars at the exchange rate prevailing on the balance sheet date and revenues and expenses were translated at the average exchange rate for the period. Foreign exchange differences resulting from the translation of this subsidiary were reported in the Consolidated Statements of Comprehensive Income/(Loss) in Other Comprehensive Income/(Loss).</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Foreign Currency </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Transactions in foreign currencies are translated to the respective functional currencies of Group entities at the foreign exchange rate ruling at the date of the transaction. Monetary assets and liabilities denominated in foreign currencies at the balance sheet date are retranslated to the functional currency at the foreign exchange rate ruling at that date. Foreign exchange differences arising on remeasurement are recognized in the Consolidated Statement of Comprehensive Income/(Loss) except for qualifying cash flow hedges, which are recognized directly in other comprehensive income. The Company did not have qualifying cash flow hedges during the reported periods. Non-monetary assets and liabilities that are measured in terms of historical cost in a foreign currency are translated using the exchange rate at the date of the transaction. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash and Cash Equivalents </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash and cash equivalents include all highly liquid instruments with original maturities of three months or less.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share Capital </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Ordinary shares are classified as equity. The Group is comprised of share capital, share premium, merger reserve, other reserve, translation reserve, and accumulated deficit.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Property and Equipment </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Property and equipment is stated at cost less accumulated depreciation and any accumulated impairment losses. Cost includes expenditures that are directly attributable to the acquisition of the asset. Assets under construction represent leasehold improvements and machinery and equipment to be used in operations or research and development activities. When parts of an item of property and equipment have different useful lives, they are accounted for as separate items (major components) of </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">property and equipment. Depreciation is calculated using the straight-line method over the estimated useful life of the related asset: </span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.566%"><tr><td style="width:1.0%"/><td style="width:48.900%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:48.900%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Laboratory and manufacturing equipment</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2-8 years</span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Furniture and fixtures</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7 years</span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Computer equipment and software</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1-5 years</span></div></td></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Leasehold improvements</span></td><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5-10 years, or the remaining term of the lease, if shorter</span></div></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation methods, useful lives and residual values are reviewed at each balance sheet date.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Intangible Assets </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Intangible assets, which include purchased patents and licenses with finite useful lives, are carried at historical cost less accumulated amortization, if amortization has commenced, and impairment losses. Intangible assets with finite lives are amortized from the time they are available for use. Amortization is calculated using the straight-line method to allocate the costs of patents and licenses over their estimated useful lives. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development intangible assets, which are still under development and have accordingly not yet obtained marketing approval, are presented as In-Process Research and Development (IPR&amp;D). IPR&amp;D is not amortized since it is not yet available for its intended use, but it is evaluated for potential impairment on an annual basis or more frequently when facts and circumstances warrant.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Impairment of Non-Financial Assets </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group reviews the carrying amounts of its property and equipment and intangible assets at each reporting date to determine whether there are indicators of impairment. If any such indicators of impairment exist, then an asset’s recoverable amount is estimated. The recoverable amount is the higher of an asset’s fair value less cost of disposal and value in use.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company’s IPR&amp;D intangible assets are not yet available for their intended use. As such, they are to be tested for impairment at least annually. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">An impairment loss is recognized when an asset’s carrying amount exceeds its recoverable amount. For the purposes of impairment testing, assets are grouped at the lowest levels for which there are largely independent cash flows. If a non- financial asset instrument is impaired, an impairment loss is recognized in the Consolidated Statements of Comprehensive Income/(Loss).</span></div><div style="margin-bottom:5.25pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company did not record any impairment of such assets during the reported periods.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investments in associates are considered impaired if, and only if, objective evidence indicates that one or more events, which occurred after the initial recognition, have had an impact on the future cash flows from the net investment and that impact can be reliably estimated. If an impairment exists the Company measures an impairment by comparing the carrying value of the net investment in the associate to its recoverable amount and recording any excess as an impairment loss. See Note 6 for impairment recorded in respect of an investment in associate during the year ended December 31, 2019. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Employee Benefits </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Short-Term Employee Benefits </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term employee benefit obligations are measured on an undiscounted basis and expensed as the related service is provided. A liability is recognized for the amount expected to be paid if the Group has a present legal or constructive obligation due to past service provided by the employee, and the obligation can be estimated reliably.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Defined Contribution Plans </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">A defined contribution plan is a post-employment benefit plan under which an entity pays fixed contributions into a separate entity and has no legal or constructive obligation to pay further amounts. Obligations for contributions to defined contribution plans are recognized as an employee benefit expense in the periods during which related services are rendered by employees. Prepaid contributions are recognized as an asset to the extent that a cash refund or a reduction in future payments is available. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Share-based Payments </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payment arrangements, in which the Group receives goods or services as consideration for its own equity instruments, are accounted for as equity-settled share-based payment transactions in accordance with IFRS 2, regardless of how the equity instruments are obtained by the Group. The grant date fair value of employee share-based payment awards is recognized as an expense with a corresponding increase in equity over the requisite service period related to the awards. The fair value is measured using an option pricing model, which takes into account the terms and conditions of the options granted. The amount recognized as an expense is adjusted to reflect the actual number of awards for which the related service and non-market performance conditions are expected to be met, such that the amount ultimately recognized as an expense is based on the number of awards that do meet the related service and non-market performance conditions at the vesting date. For share-based payment awards with market conditions, the grant date fair value is measured to reflect such conditions and there is no true-up for differences between expected and actual outcomes.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Development Costs </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expenditures on research activities are recognized as incurred in the Consolidated Statements of Comprehensive Income/(Loss). In accordance with IAS 38 development costs are capitalized only if the expenditure can be measured reliably, the product or process is technically and commercially feasible, future economic benefits are probable, the Group can demonstrate its ability to use or sell the intangible asset, the Group intends to and has sufficient resources to complete development and to use or sell the asset, and it is able to measure reliably the expenditure attributable to the intangible asset during its development. The point at which technical </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">feasibility is determined to have been reached is when regulatory approval has been received where applicable. Management determines that commercial viability has been reached when a clear market and pricing point have been identified, which may coincide with achieving meaningful recurring sales. Otherwise, the development expenditure is recognized as incurred in the Consolidated Statements of Comprehensive Income/(Loss). As of balance sheet date the Group has not capitalized any development costs.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Provisions </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">A provision is recognized in the Consolidated Statements of Financial Position when the Group has a present legal or constructive obligation due to a past event that can be reliably measured, and it is probable that an outflow of economic benefits will be required to settle the obligation. Provisions are determined by discounting the expected future cash flows at a pre-tax rate that reflects risks specific to the liability.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Leases</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On January 1, 2019, the Group adopted a new accounting standard for leases. The Group leases real estate and equipment for use in operations. These leases generally have lease terms of 1 to 10 years. The Group includes options that are reasonably certain to be exercised as part of the determination of the lease term. The group determines if an arrangement is a lease at inception of the contract in accordance with guidance detailed in the new standard. ROU assets represent the Group’s right to use an underlying asset for the lease term and lease liabilities represent our obligation to make lease payments arising from the lease. Operating lease ROU assets and liabilities are recognized at commencement date based on the present value of lease payments over the lease term. As most of our leases do not provide an implicit rate, we use the Group’s estimated incremental borrowing rate based on information available at commencement date in determining the present value of future payments. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s operating leases are virtually all leases from real estate.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">When adopting IFRS 16 on January 1, 2019 , the Group has applied a modified retrospective approach by measuring the right-of-use asset at an amount equal to the lease liability at the date of transition and therefore comparative information was not restated. Upon transition, the Group has applied the following practical expedients:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">excluding initial direct costs from the right-of-use assets;</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">using hindsight when assessing the lease term; and</span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">not reassessing whether a contract is or contains a lease; </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group has elected to account for lease payments as an expense on a straight-line basis over the life of the lease for: </span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Leases with a term of 12 months or less and containing no purchase options; and </span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Leases where the underlying asset has a value of less than $5,000. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The lease liability was initially measured at the present value of the lease payments that were not paid at the transition date, discounted by using the Group's incremental borrowing rate as the rate implicit in the lease was not readily determinable.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The right-of-use asset is depreciated on a straight-line basis and the lease liability will give rise to an interest charge. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The financial impact of adopting IFRS 16 on the Group was primarily as follows:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:87.080%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.720%"/><td style="width:0.1%"/></tr><tr style="height:12pt"><td colspan="3" rowspan="2" style="padding:0 1pt"><div style="margin-bottom:6pt;text-align:justify"><span><br/></span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">January 1, 2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:12pt"><td colspan="6" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Right of use asset</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,353</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Lease liability</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,995</span></td></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Accumulated deficit</span></td><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">999 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Further information regarding the subleases, right of use asset and lease liability can be found in Note 21.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance Income and Finance Costs </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance income is comprised of income on funds invested in U.S. treasuries, income on money market funds and to a much lesser extent income on a finance lease. Financing income is recognized as it is earned. Finance costs comprise mainly of loan and lease liability interest expenses and the changes in the fair value of warrant and financial liabilities carried at FVTPL.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Taxation </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax on the profit or loss for the year comprises current and deferred income tax. In accordance with IAS 12, tax is recognized in the Consolidated Statements of Comprehensive Income/(Loss) except to the extent that it relates to items recognized directly in equity.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Current income tax is the expected tax payable or receivable on the taxable income or loss for the year, using tax rates enacted or substantially enacted at the reporting date, and any adjustment to tax payable in respect of previous years.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax is recognized due to temporary differences between the carrying amounts of assets and liabilities for financial reporting purposes and the amounts used for taxation purposes. Deferred tax assets are recognized for unused tax losses, unused tax credits and deductible temporary differences to the extent that it is probable that future taxable profits will be available against which they can be used. Deferred tax assets are reviewed at each reporting date and are reduced to the extent that it is no longer probable that the related tax benefit will be realized.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax is measured at the tax rates that are expected to be applied to temporary differences when they reverse, using tax rates enacted or substantively enacted at the reporting date.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred income tax assets and liabilities are offset when there is a legally enforceable right to offset current tax assets against current tax liabilities and when the deferred income tax assets and liabilities relate to income taxes levied by the same taxation authority on either the same taxable entity or different taxable entities where there is an intention to settle the balances on a net basis.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred taxes are recognized in Consolidated Statements of Comprehensive Income/(Loss) except to the extent that they relate to items recognized directly in equity or in other comprehensive income.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair Value Measurements </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s accounting policies require that certain financial and non-financial assets and certain financial liabilities be measured at their fair value.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group uses valuation techniques that are appropriate in the circumstances and for which sufficient data are available to measure fair value, maximizing the use of relevant observable inputs and minimizing the use of unobservable inputs. Fair values are categorized into different levels in a fair value hierarchy based on the inputs used in the valuation techniques as follows:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Level 1: quoted prices (unadjusted) in active markets for identical assets or liabilities.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Level 2: inputs other than quoted prices included in Level 1 that are observable for the asset or liability, either directly (i.e. as prices) or indirectly (i.e. derived from prices).</span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Level 3: inputs for the asset or liability that are not based on observable market data (unobservable inputs).</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group recognizes transfers between levels of the fair value hierarchy at the end of the reporting period during which the change has occurred.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The carrying amount of cash and cash equivalents, accounts receivable, restricted cash, deposits, accounts payable, accrued expenses and other current liabilities in the Group’s Consolidated Statements of Financial Position approximates their fair value because of the short maturities of these instruments. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Operating Segments </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Operating segments are reported in a manner that is consistent with the internal reporting provided to the chief operating decision maker (“CODM”). The CODM reviews discrete financial information for the operating segments in order to assess their performance and is responsible for making decisions about resources allocated to the segments. The CODM has been identified as the Group’s Directors.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Prior period reclassification </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During 2019 management identified that for the year ended December 31, 2018, Gain/(loss) on investments held at fair value of $14.3 million was incorrectly classified as Finance costs – subsidiary preferred shares. As a result, in the 2019 financial statements a prior year reclassification has been made in the Consolidated Statement of Comprehensive Income/(Loss) for the year ended December 31, 2018.</span></div> <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Basis of Presentation</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The consolidated financial statements of the Group are presented as of December 31, 2020 and 2019 and for the years ended December 31, 2020, 2019 and 2018. The Group financial statements have been approved by the Directors on April 14, 2021 and are prepared in accordance with international accounting standards in conformity with the requirements of the Companies Act 2006 and International Financial Reporting Standards (IFRSs) adopted pursuant to Regulation (EC) No 1606/2002 as it applies in the EU. The Consolidated Financial Statements also comply fully with IFRSs as issued by the International Accounting Standards Board (IASB). IFRSs as adopted pursuant to Regulation (EC) No 1606/2002 as it applies in the EU differs in certain respects from IFRS as issued by the IASB. However, the differences have no impact for the periods presented.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For presentation of the Consolidated Statements of Comprehensive Income/(Loss), the Company uses a classification based on the function of expenses, rather than based on their nature, as it is more representative of the format used for internal reporting and management purposes and is consistent with international practice.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Certain amounts in the Consolidated Financial Statements and accompanying notes may not add due to rounding. All percentages have been calculated using unrounded amounts.</span></div> <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Basis of Measurement </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The consolidated financial statements are prepared on the historical cost basis except that the following assets and liabilities are stated at their fair value: investments held at fair value and liabilities classified as fair value through the profit or loss. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Use of Judgments and Estimates </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In preparing these consolidated financial statements, management has made judgements, estimates and assumptions that affect the application of the Group’s accounting policies and the reported amounts of assets, liabilities, income and expenses. Actual results may differ from these estimates. Estimates and underlying assumptions are reviewed on an on-going basis.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Significant estimation applied in determining the following:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Financial instruments valuations (Note 16): when estimating the fair value of subsidiary convertible notes and subsidiary preferred shares carried at fair value through profit and loss (FVTPL) and investments held at fair value, at initial recognition and upon subsequent measurement. This includes determining the appropriate valuation methodology and making certain estimates of the future earnings potential of the subsidiary businesses, appropriate discount rate and earnings multiple to be applied, marketability and other industry and company specific risk factors. See Note 16 for the sensitivity analysis for key estimates used in these valuations.</span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Valuation of share based payments (Note 8): when estimating the fair value of share based payment on grant date. This includes making certain estimates regarding the expected life of the share-based award, share price volatility, risk free interest rate as well as other covariance of comparable public companies and other market data to predict distribution of relative share performance.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Significant judgement is also applied in determining the following:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Revenue recognition (Note 3): when determining the correct amount of revenue to be recognized. This includes making certain judgements when determining the appropriate accounting treatment of key customer contract terms in accordance with the applicable accounting standards. In particular, judgement is required to determine the performance obligations in a contract (if promised goods and services are distinct or not) and timing of revenue recognition (on delivery or over a period of time).</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Subsidiary preferred shares liability classification (Note 15): when determining the classification of financial instruments in terms of liability or equity. These judgements include an assessment of whether the financial instrument include any embedded derivative features, whether they include contractual obligations upon the Group to deliver cash or other financial assets or to exchange financial assets or financial liabilities with another party, and whether that obligation will be settled by the Company exchanging a fixed amount of cash or other financial assets for a fixed number of its own equity instruments. Further information about these critical judgements and estimates is included below under Financial Instruments.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">When the power to control the subsidiaries exists (please refer to Notes 5 and 6 and accounting policy below Subsidiaries). This judgement includes an assessment of whether the Company has (i) power over the investee; (ii) exposure, or rights, to variable returns from its involvement with the investee; and (iii) the ability to use its power over the investee to affect the amount of the investor’s returns. The Company considers among others its voting shares, representation on the board, rights to appoint management, investee dependence on the Company etc. If the power to control investees exists we consolidate the financial statements of such investee in the consolidated financial statements of the Group. Upon issuance of new shares in a subsidiary </span></div><div style="padding-left:11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">and a resulting change in any shareholders or governance agreements, the Group reassesses its ability to control the investee based on the revised board composition and revised subsidiary governance and management structure. When such new circumstances result in the Group losing its power to control the investee, the investee is deconsolidated.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Whether the Company has significant influence over financial and operating policies of investees in order to determine if the Company should account for its investment as an associate based on IAS 28 or based on IFRS 9, Financial Instruments (please refer to Note 5). This judgement includes, among others, an assessment whether the Company has representation on the board of directors of the investee, whether the Company participates in the policy making processes of the investee, whether there is any interchange of managerial personnel, whether there is any essential technical information provided to the investee and if there are any transactions between the Company and the investee.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Upon determining that the Company does have significant influence over the financial and operating policies of an investee, if the Company holds more than a single instrument issued by its equity-accounted investee, judgement is required to determine whether the additional instrument forms part of the investment in the associate, which is accounted for under IAS 28 and scoped out of IFRS 9, or it is a separate financial instrument that falls in the scope of IFRS 9 (please refer to Notes 5 and 6). This judgement includes an assessment of the characteristics of the financial instrument of the investee held by the Company and whether such financial instrument provides access to returns underlying an ownership interest.</span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Where the company has other investments in an equity accounted investee that are not accounted for under IAS 28, judgement is required in determining if such investments constitute Long-Term Interests for the purposes of IAS 28 (please refer to Notes 5 and 6). This determination is based on the individual facts and circumstances and characteristics of each investment, but is driven, among other factors, by the intention and likelihood to settle the instrument through redemption or repayment in the foreseeable future, and whether or not the investment is likely to be converted to common stock or other equity instruments (please also refer to accounting policy with regard to Investments in Associates below). When considering the individual facts and circumstances of the Group’s investment in its associate's preferred stock in the manner described above, including the long-term nature of such investment, the ability of the Group to convert its preferred stock investment to an investment in common shares and the likelihood of such conversion, as well the fact that there is no planned redemption or other settlement of the preferred stock by the investee in the foreseeable future, we concluded that such investment is considered a Long Term Interest.</span></div> <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of December 31, 2020 the Group had cash and cash equivalents of $403.9 million. Considering the Group’s and the Company's financial position as of December 31, 2020 and its principal risks and opportunities, a going concern analysis has been prepared for at least the twelve-month period from the date of signing the Consolidated Financial Statements ("the going concern period") utilizing realistic scenarios and applying a severe but plausible downside scenario. Even under the downside scenario, the analysis demonstrates the Group and the Company continue to maintain sufficient liquidity headroom and continues to comply with all financial obligations. On February 9, 2021, the Group sold 1,000,000 common shares of Karuna for aggregate proceeds of $118.0 million, further strengthening the liquidity headroom of the Group. Therefore, the Directors believe the Group and the Company is adequately resourced to continue in operational existence for at least the twelve-month period from the date of signing the Consolidated Financial Statements, irrespective of uncertainty regarding the duration and severity of the COVID-19 pandemic and the global macroeconomic impact of the pandemic. Accordingly, the Directors considered it appropriate to adopt the going concern basis of accounting in preparing the Consolidated Financial Statements and the PureTech Health plc Financial Statements. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Basis of consolidation</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The consolidated financial information as of December 31, 2020 and 2019 and for each of the years ended December 31, 2020, 2019 and 2018 comprises an aggregation of financial information of the Company and the consolidated financial information of PureTech Health LLC (“PureTech LLC”). Intra-group balances and transactions, and any unrealized income and expenses arising from intra-group transactions, are eliminated.</span></div> 403900000 1000000 118000000.0 <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiaries </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As used in these financial statements, the term subsidiaries refers to entities that are controlled by the Group. Financial results of subsidiaries of the Group as of December 31, 2020 are reported within the Internal segment, Controlled Founded Entities segment or the Parent Company and Other segment (please refer to Note 4). Under applicable accounting rules, the Group controls an entity when it is exposed to, or has the rights to, variable returns from its involvement with the entity and has the ability to affect those returns through its power over the entity. In assessing control, the Group takes into consideration potential voting rights and board interest and holding. The financial statements of subsidiaries are included in the consolidated financial statements from the date that control commences until the date that control ceases. Losses applicable to the non-controlling interests in a subsidiary are allocated to the non-controlling interests even if doing so causes the non-controlling interests to have a deficit balance.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">A list of all current and former subsidiaries organized with respect to classification as of December 31, 2020 and the Group’s total voting percentage, based on outstanding voting common and preferred shares as of December 31, 2020, 2019 and 2018, is outlined below. All current subsidiaries are domiciled within the United States and conduct business activities solely within the United States. </span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:41.668%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.233%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="24" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Voting percentage at December 31, through the holdings in</span></div></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="6" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="6" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Subsidiary</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Common</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"><span style="font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%"> Preferred</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Common</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"><span style="font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%"> Preferred</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Common</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"><span style="font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%"> Preferred</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Subsidiary operating companies</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Alivio Therapeutics, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">91.9</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">91.9 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">92.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega, Inc. (indirectly held through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">83.1</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">83.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">83.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica, Incorporated</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2,5</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">28.7</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">56.7</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">56.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4.4 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">79.2 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:41.668%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.233%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech LYT (formerly Ariya Therapeutics, Inc.)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">8</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech LYT-100</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Management, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">3</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Health LLC</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">3</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde Health, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">51.8</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">64.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">96.4 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta Biosciences, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">59.3</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">61.8 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">74.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta Biosciences Securities Corp. (indirectly held through Vedanta)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">59.3</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">61.8 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">74.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Deconsolidated former subsidiary operating companies</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Akili Interactive Labs, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2,7</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">41.9</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41.9 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41.9 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2,9</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4.9</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">20.2</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">20.2 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">18.4 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Karuna Pharmaceuticals, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2,10</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">12.6</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.4 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">71.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vor Biopharma Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2,11</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">16.4</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">47.5 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">93.2 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Nontrading holding companies</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:justify"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.4pt;font-weight:400;line-height:120%">Endra Holdings, LLC (held indirectly through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.46pt;font-weight:400;line-height:120%;position:relative;top:-2.94pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:justify"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.4pt;font-weight:400;line-height:120%">Ensof Holdings, LLC (held indirectly through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.46pt;font-weight:400;line-height:120%;position:relative;top:-2.94pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Securities Corp.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Securities II Corp.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Inactive subsidiaries</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Appeering, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Commense Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2,6</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">99.1</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">99.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">99.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Enlight Biosciences, LLC</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8pt;font-weight:400;line-height:120%">Ensof Biosystems, Inc. (held indirectly through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.2pt;font-weight:400;line-height:120%;position:relative;top:-2.8pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">57.7</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">28.3</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">57.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">57.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Knode Inc. (indirectly held through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Libra Biosciences, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Mandara Sciences, LLC</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">98.3</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">98.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">98.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tal Medical, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">64.5 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    The voting percentage is impacted by preferred shares that are classified as liabilities, which results in the ownership percentage not being the same as the ownership percentage used in allocations to non-controlling interests disclosed in Note 18. The allocation of losses/profits to the noncontrolling interest is based on the holdings of subordinated stock that provide ownership rights in the subsidiaries. The ownership of liability classified preferred shares are quantified in Note 15.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Registered address is Corporation Trust Center, 1209 Orange St., Wilmington, DE 19801, USA.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">3    Registered address is 2711 Centerville Rd., Suite 400, Wilmington, DE 19808, USA.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">4    The Company’s interests in its subsidiaries are predominantly in the form of preferred shares, which have a liquidation preference over the common stock, are convertible into common stock at the holder’s discretion or upon certain liquidity events, are entitled to one vote per share on all matters submitted to shareholders for a vote and entitled to receive dividends when and if declared. In the case of Enlight, Mandara and PureTech Health LLC, the holdings are membership interests in an LLC. The holders of common stock are entitled to one vote per share on all matters submitted to shareholders for a vote and entitled to receive dividends when and if declared.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">5    On July 19, 2019, all of the outstanding notes, plus accrued interest, issued by Follica to PureTech converted into 15,216,214 shares of Series A-3 Preferred Shares and 12,777,287 shares of common share pursuant to a Series A-3 Note Conversion Agreement between Follica and the noteholders. Please refer to Note 16.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">6    Commense turned inactive during 2019.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">7    On May 8, 2018, PureTech lost control of Akili, Akili was deconsolidated from the Group’s financial statements and is no longer considered a subsidiary. This results in only the profits and losses generated by Akili through the deconsolidation date being included in the Group’s Consolidated Statement of Income/(Loss) and Other Comprehensive Income/(Loss). See Note 5 for further details about the accounting for the investment in Akili subsequent to deconsolidation.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">8    On July 18, 2018, Calix Biopharma, Inc., Glyph Biosciences, Inc., and Nybo Therapeutics, Inc. merged into Ariya Therapeutics, Inc. Thus, the Group no longer holds an interest in Calix, Glyph and Nybo but rather owns 100.0 percent voting interest of Ariya.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">9    As of December 31, 2018, PureTech maintained control of Gelesis. On July 1, 2019 PureTech lost control of Gelesis and Gelesis was deconsolidated from the Group’s financial statements, resulting in only the profits and losses generated by Gelesis through the deconsolidation date being included in the Group’s Consolidated Statement of Income/(Loss) and Other Comprehensive Income/(Loss). See Notes 5 and 6 for further details about the accounting for the investments in Gelesis subsequent to deconsolidation.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">10    On March 15, 2019, PureTech lost control of Karuna, Karuna was deconsolidated from the Group’s financial statements and is no longer considered a subsidiary. This results in only the profits and losses generated by Karuna through the deconsolidation date being included in the Group’s Consolidated Statement of Income/(Loss) and Other Comprehensive Income/(Loss). See Note 5 for further details about the accounting for the investment in Karuna subsequent to deconsolidation.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">11    On February 12, 2019, PureTech lost control of Vor, Vor was deconsolidated from the Group’s financial statements and is no longer considered a subsidiary. This results in only the profits and losses generated by Vor through the deconsolidation date being included in the Group’s Consolidated Statement of Income/(Loss) and Other Comprehensive Income/(Loss).See Note 5 for further details about the accounting for the investment in Vor subsequent to deconsolidation.</span></div><div style="margin-bottom:5.25pt"><span><br/></span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in subsidiary ownership and loss of control </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Changes in the Group’s interest in a subsidiary that do not result in a loss of control are accounted for as equity transactions.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Where the Group loses control of a subsidiary, the assets and liabilities are derecognized along with any related non-controlling interest (“NCI”). Any interest retained in the former subsidiary is measured at fair value when control is lost. Any resulting gain or loss is recognized as profit or loss in the Consolidated Statements of Comprehensive Income/(Loss).</span></div> All current subsidiaries are domiciled within the United States and conduct business activities solely within the United States. <table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:41.668%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.233%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="24" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Voting percentage at December 31, through the holdings in</span></div></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="6" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="6" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Subsidiary</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Common</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"><span style="font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%"> Preferred</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Common</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"><span style="font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%"> Preferred</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Common</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"><span style="font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%"> Preferred</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Subsidiary operating companies</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Alivio Therapeutics, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">91.9</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">91.9 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">92.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega, Inc. (indirectly held through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">83.1</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">83.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">83.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica, Incorporated</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2,5</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">28.7</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">56.7</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">56.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4.4 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">79.2 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:41.668%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.231%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.233%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech LYT (formerly Ariya Therapeutics, Inc.)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">8</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech LYT-100</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Management, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">3</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Health LLC</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">3</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde Health, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">51.8</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">64.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">96.4 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta Biosciences, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">59.3</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">61.8 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">74.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta Biosciences Securities Corp. (indirectly held through Vedanta)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">59.3</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">61.8 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">74.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Deconsolidated former subsidiary operating companies</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Akili Interactive Labs, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2,7</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">41.9</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41.9 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41.9 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2,9</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4.9</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">20.2</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">20.2 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">18.4 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Karuna Pharmaceuticals, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2,10</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">12.6</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.4 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">71.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vor Biopharma Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2,11</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">16.4</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">47.5 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">93.2 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Nontrading holding companies</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:justify"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.4pt;font-weight:400;line-height:120%">Endra Holdings, LLC (held indirectly through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.46pt;font-weight:400;line-height:120%;position:relative;top:-2.94pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:justify"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.4pt;font-weight:400;line-height:120%">Ensof Holdings, LLC (held indirectly through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.46pt;font-weight:400;line-height:120%;position:relative;top:-2.94pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Securities Corp.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Securities II Corp.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Inactive subsidiaries</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Appeering, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Commense Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2,6</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">99.1</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">99.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">99.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Enlight Biosciences, LLC</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8pt;font-weight:400;line-height:120%">Ensof Biosystems, Inc. (held indirectly through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.2pt;font-weight:400;line-height:120%;position:relative;top:-2.8pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">57.7</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">28.3</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">57.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">57.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Knode Inc. (indirectly held through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Libra Biosciences, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Mandara Sciences, LLC</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">98.3</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">98.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">98.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tal Medical, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">64.5 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    The voting percentage is impacted by preferred shares that are classified as liabilities, which results in the ownership percentage not being the same as the ownership percentage used in allocations to non-controlling interests disclosed in Note 18. The allocation of losses/profits to the noncontrolling interest is based on the holdings of subordinated stock that provide ownership rights in the subsidiaries. The ownership of liability classified preferred shares are quantified in Note 15.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Registered address is Corporation Trust Center, 1209 Orange St., Wilmington, DE 19801, USA.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">3    Registered address is 2711 Centerville Rd., Suite 400, Wilmington, DE 19808, USA.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">4    The Company’s interests in its subsidiaries are predominantly in the form of preferred shares, which have a liquidation preference over the common stock, are convertible into common stock at the holder’s discretion or upon certain liquidity events, are entitled to one vote per share on all matters submitted to shareholders for a vote and entitled to receive dividends when and if declared. In the case of Enlight, Mandara and PureTech Health LLC, the holdings are membership interests in an LLC. The holders of common stock are entitled to one vote per share on all matters submitted to shareholders for a vote and entitled to receive dividends when and if declared.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">5    On July 19, 2019, all of the outstanding notes, plus accrued interest, issued by Follica to PureTech converted into 15,216,214 shares of Series A-3 Preferred Shares and 12,777,287 shares of common share pursuant to a Series A-3 Note Conversion Agreement between Follica and the noteholders. Please refer to Note 16.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">6    Commense turned inactive during 2019.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">7    On May 8, 2018, PureTech lost control of Akili, Akili was deconsolidated from the Group’s financial statements and is no longer considered a subsidiary. This results in only the profits and losses generated by Akili through the deconsolidation date being included in the Group’s Consolidated Statement of Income/(Loss) and Other Comprehensive Income/(Loss). See Note 5 for further details about the accounting for the investment in Akili subsequent to deconsolidation.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">8    On July 18, 2018, Calix Biopharma, Inc., Glyph Biosciences, Inc., and Nybo Therapeutics, Inc. merged into Ariya Therapeutics, Inc. Thus, the Group no longer holds an interest in Calix, Glyph and Nybo but rather owns 100.0 percent voting interest of Ariya.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">9    As of December 31, 2018, PureTech maintained control of Gelesis. On July 1, 2019 PureTech lost control of Gelesis and Gelesis was deconsolidated from the Group’s financial statements, resulting in only the profits and losses generated by Gelesis through the deconsolidation date being included in the Group’s Consolidated Statement of Income/(Loss) and Other Comprehensive Income/(Loss). See Notes 5 and 6 for further details about the accounting for the investments in Gelesis subsequent to deconsolidation.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">10    On March 15, 2019, PureTech lost control of Karuna, Karuna was deconsolidated from the Group’s financial statements and is no longer considered a subsidiary. This results in only the profits and losses generated by Karuna through the deconsolidation date being included in the Group’s Consolidated Statement of Income/(Loss) and Other Comprehensive Income/(Loss). See Note 5 for further details about the accounting for the investment in Karuna subsequent to deconsolidation.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">11    On February 12, 2019, PureTech lost control of Vor, Vor was deconsolidated from the Group’s financial statements and is no longer considered a subsidiary. This results in only the profits and losses generated by Vor through the deconsolidation date being included in the Group’s Consolidated Statement of Income/(Loss) and Other Comprehensive Income/(Loss).See Note 5 for further details about the accounting for the investment in Vor subsequent to deconsolidation.</span></div> 0.919 0.919 0.920 0.831 0.831 0.831 0.287 0.567 0.287 0.567 0.044 0.792 1.000 1.000 1.000 1.000 1.000 1.000 1.000 1.000 1.000 1.000 1.000 1.000 0.518 0.641 0.964 0.593 0.618 0.743 0.593 0.618 0.743 0.419 0.419 0.419 0.049 0.202 0.057 0.202 0.073 0.184 0.126 0 0.284 0 0.710 0.164 0.475 0.932 0.860 0.860 0.860 0.860 0.860 0.860 1.000 1.000 1.000 1.000 1.000 1.000 1.000 0.991 0.991 0.991 0.860 0.860 0.860 0.577 0.283 0.577 0.283 0.577 0.283 0.860 0.860 0.860 1.000 1.000 1.000 0.983 0.983 0.983 1.000 1.000 0.645 15216214 12777287 <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Associates </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As used in these financial statements, the term associates are those entities in which the Group has no control but maintains significant influence over the financial and operating policies. Significant influence is presumed to exist when the Group holds between 20 and 50 percent of the voting power of an entity, unless it can be clearly demonstrated that this is not the case. The Group evaluates if it maintains significant influence over associates by assessing if the Group has lost the power to participate in the financial and operating policy decisions of the associate.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Application of the equity method to associates </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Associates are accounted for using the equity method (equity accounted investees) and are initially recognized at cost, or if recognized upon deconsolidation they are initially recorded at fair value at the date of deconsolidation. The consolidated financial statements include the Group’s share of the total comprehensive income and equity movements of equity accounted investees, from the date that significant influence commences until the date that significant influence ceases. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">To the extent the Group holds interests in associates that are not providing access to returns underlying ownership interests, the instrument held by PureTech is accounted for in accordance with IFRS 9 as investments held at fair value.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">When the Group’s share of losses exceeds its equity method investment in the investee, losses are applied against Long-Term Interests, which are investments accounted for under IFRS 9. Investments are determined to be Long-Term Interests when they are long-term in nature and in substance they form part of the Group's net investment in that associate. This determination is impacted by many factors, among others, whether settlement by the investee through redemption or repayment is planned or likely in the foreseeable future, whether the investment can be converted and/or is likely to be converted to common stock or other equity instrument and other factors regarding the nature of the investment. Whilst this assessment is dependent on many specific facts and circumstances of each investment, typically conversion features whereby the investment is likely to convert to common stock or other equity instruments would point to the investment being a Long-Term Interest. Similarly, where the investment is not planned or likely to be settled through redemption or repayment in the foreseeable future, this would indicate that the investment is a Long-Term Interest. When the net investment in the associate, which includes the Group’s investments in other long-term interests, is reduced to nil, recognition of further losses is discontinued except to the extent that the Group has incurred legal or constructive obligations or made payments on behalf of an investee.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group has also adopted the amendments to IAS 28 Investments in Associates that addresses the dual application of IAS 28 and IFRS 9 (see below) when equity method losses are applied against Long-Term Interests (LTI). The amendments provide the annual sequence in which both standards are to be applied in such a case. The Group has applied the equity method losses to the LTIs presented as part of Investments held at fair value subsequent to remeasuring such investments to their fair value at balance sheet date.</span></div> <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in Accounting Policy </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of January 1, 2019, the Group has adopted new accounting policies for the accounting for leases. See updated accounting policy for leases (IFRS 16) below.</span></div> <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial Instruments </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Classification </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group classifies its financial assets in the following measurement categories:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Those to be measured subsequently at fair value (either through other comprehensive income, or through profit or loss), and</span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Those to be measured at amortized cost.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The classification depends on the Group’s business model for managing the financial assets and the contractual terms of the cash flows.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For assets measured at fair value, gains and losses will are recorded in profit or loss. For investments in debt instruments, this will depend on the business model in which the investment is held. For investments in equity instruments that are not held for trading, this will depend on whether the Group has made an irrevocable election at the time of initial recognition to account for the equity investment at FVOCI. As of balance sheet dates, none of the Company's financial assets are accounted for as FVOCI.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Measurement </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">At initial recognition, the Group measures a financial asset at its fair value plus, in the case of a financial asset not at FVTPL, transaction costs that are directly attributable to the acquisition of the financial asset. Transaction costs of financial assets that are carried at FVTPL are expensed.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group assesses on a forward-looking basis the expected credit losses associated with its debt instruments carried at amortized cost. The Group had no debt instruments carried at amortized cost as of balance sheet date. For trade receivables, the Group applies the simplified approach permitted by IFRS 9, which requires expected lifetime losses to be recognized from initial recognition of the receivables.</span></div> <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial Assets </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s financial assets consist of cash and cash equivalents, trade and other receivables, debt and equity securities, other deposits and investments in associates’ preferred shares. The Group’s financial assets are classified into the following categories: investments held at fair value, trade and other receivables, short-term investments and cash and cash equivalents. The Group determines the classification of financial assets at initial recognition depending on the purpose for which the financial assets were acquired.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investments held at fair value are investments in equity instruments that are not held for trading. Such investments consist of the Group's minority interest holdings where the Group has no significant influence or preferred share investments in the Group's associates that are not providing access to returns underlying ownership interests. These financial assets are initially measured at fair value and subsequently re-measured at fair value at each reporting date. The Company elects if the gain or loss will be recognized in Other Comprehensive Income/(Loss) or through profit and loss on an instrument by instrument basis. The Company has elected to record the changes in fair values for the financial assets falling under this category through profit and loss. Please refer to Note 5.</span></div><div style="margin-bottom:5.25pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term investments are short-term government treasury bonds carried at fair value with changes in fair value recorded through profit and loss in financing income.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Changes in the fair value of financial assets at FVTPL are recognized in other income/(expense) in the Consolidated Statements of Comprehensive Income/(Loss) as applicable. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other receivables are non-derivative financial assets with fixed and determinable payments that are not quoted on active markets. These financial assets are carried at the amounts expected to be received less any expected lifetime losses. Such losses are determined taking into account previous experience, credit rating and economic stability of counterparty and economic conditions. When a trade receivable is determined to be uncollectible, it is written off against the available provision. Trade and other receivables are included in current assets, unless maturities are greater than 12 months after the end of the reporting period.</span></div> <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial Liabilities </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s financial liabilities consist of trade and other payables, subsidiary notes payable, preferred shares, and warrant liability. Warrant liabilities are initially recognized at fair value. After initial recognition, these financial liabilities are re-measured at FVTPL using an appropriate valuation technique. Subsidiary notes payable without embedded derivatives are accounted for at amortized cost.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The majority of the Group’s subsidiaries have preferred shares and notes payable with embedded derivatives, which are classified as current liabilities. When the Group has preferred shares and notes with embedded derivatives that qualify for bifurcation, the Group has elected to account for the entire instrument as FVTPL after determining under IFRS 9 that the instrument qualifies to be accounted for under such FVTPL method.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group derecognizes a financial liability when its contractual obligations are discharged, cancelled or expire.</span></div> <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Equity Instruments Issued by the Group </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial instruments issued by the Group are treated as equity only to the extent that they meet the following two conditions, in accordance with IAS 32:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:4.26pt">They include no contractual obligations upon the Group to deliver cash or other financial assets or to exchange financial assets or financial liabilities with another party under conditions that are potentially unfavorable to the Group; and</span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:4.26pt">Where the instrument will or may be settled in the Group’s own equity instruments, it is either a non-derivative that includes no obligation to deliver a variable number of the Group’s own equity instruments or is a derivative that will be settled by the Group exchanging a fixed amount of cash or other financial assets for a fixed number of its own equity instruments.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">To the extent that this definition is not met, the financial instrument is classified as a financial liability. Where the instrument so classified takes the legal form of the Group’s own shares, the amounts presented in the financial information for share capital and merger reserve account exclude amounts in relation to those shares.</span></div>Changes in the fair value of liabilities at FVTPL are recognized in Net finance income (costs) in the Consolidated Statements of Comprehensive Income/(Loss) as applicable. <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">IFRS 15, Revenue from Contracts with Customers </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The standard establishes a five-step principle-based approach for revenue recognition and is based on the concept of recognizing an amount that reflects the consideration for performance obligations only when they are satisfied and the control of goods or services is transferred.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The majority of the Group’s contract revenue is generated from licenses and services, some of which are part of collaboration arrangements. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Management reviewed contracts where the Group received consideration in order to determine whether or not they should be accounted for in accordance with IFRS 15. To date, PureTech has entered into transactions that generate revenue and meet the scope of either IFRS 15 or IAS 20 Accounting for Government Grants. Contract revenue is recognized at either a point-in-time or over time, depending on the nature of the services and existence of acceptance clauses.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group accounts for agreements that meet the definition of IFRS 15 by applying the following five step model:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Identify the contract(s) with a customer – A contract with a customer exists when (i) the Group enters into an enforceable contract with a customer that defines each party’s rights regarding the goods or services to be transferred and identifies the payment terms related to those goods or services, (ii) the contract has commercial substance and, (iii) the Group determines that collection of substantially all consideration for goods or services that are transferred is probable based on the customer’s intent and ability to pay the promised consideration.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Identify the performance obligations in the contract – Performance obligations promised in a contract are identified based on the goods or services that will be transferred to the customer that are both capable of being distinct, whereby the customer can benefit from the good or service either on its own or together with other resources that are readily available from third parties or from the Group, and are distinct in the context of the contract, whereby the transfer of the goods or services is separately identifiable from other promises in the contract.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Determine the transaction price – The transaction price is determined based on the consideration to which the Group will be entitled in exchange for transferring goods or services to the customer. To the extent the transaction price includes variable consideration, the Group estimates the amount of variable consideration that should be included in the transaction price utilizing either the expected value method or the most likely amount method depending on the nature of the variable consideration. Variable consideration is included in the transaction price if, in the Group’s judgement, it is probable that a significant future reversal of cumulative revenue under the contract will not occur. </span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Allocate the transaction price to the performance obligations in the contract – If the contract contains a single performance obligation, the entire transaction price is allocated to the single performance obligation. Contracts that contain multiple performance obligations require an allocation of the transaction price to each performance obligation based on a relative standalone selling price basis. </span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Recognize revenue when (or as) the Group satisfies a performance obligation – The Group satisfies performance obligations either over time or at a point in time as discussed in further detail below. Revenue is recognized at the time the related performance obligation is satisfied by transferring a promised good or service to a customer.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Revenue generated from services agreements (typically where licenses and related services were combined into one performance obligation) is determined to be recognized over time when it can be determined that the services meet one of the following: (a) the customer simultaneously receives and consumes the benefits provided by the entity’s performance as the entity performs; (b) the entity’s performance creates or enhances an asset that the customer controls as the asset is created or enhanced; or (c) the entity’s performance does not create an asset with an alternative use to the entity and the entity has an enforceable right to payment for performance completed to date.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">It was determined that the Group has contracts that meet criteria (a), since the customer simultaneously receives and consumes the benefits provided by the Company’s performance as the Company performs. Therefore revenue is recognized over time using the input method based on costs incurred to date as compared to total contract costs. The Company believes that in research and development service type agreements using costs incurred to date represents the most faithful depiction of the entity’s performance towards complete satisfaction of a performance obligation.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Revenue from licenses that are not part of a combined performance obligation are recognized at a point in time due to the licenses relating to intellectual property that has significant stand-alone functionality and as such represent a right to use the entity's intellectual property as it exists at the point in time at which the license is granted.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amounts that are receivable or have been received per contractual terms but have not been recognized as revenue since performance has not yet occurred or has not yet been completed are recorded as deferred revenue. The Company classifies as non-current deferred revenue amounts received for which performance is expected to occur beyond one year or one operating cycle.</span></div> <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant Income </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company recognizes grants from governmental agencies as grant income in the Consolidated Statement of Comprehensive Income/(Loss), gross of the expenditures that were related to obtaining the grant, when there is reasonable assurance that the Company will comply with the conditions within the grant agreement and there is reasonable assurance that payments under the grants will be received. The Company evaluates the conditions of each grant as of each reporting date to ensure that the Company has reasonable assurance of meeting the conditions of each grant arrangement and it is expected that the grant payment will be received as a result of meeting the necessary conditions.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company submits qualifying expenses for reimbursement after the Company has incurred the research and development expense. The Company records an unbilled receivable upon incurring such expenses. In cases were grant income is received prior to the expenses being incurred or recognized, the amounts received are deferred until the related expense is incurred and/or recognized. Grant income is recognized in the Consolidated Statements of Comprehensive Income/(Loss) over the periods in which the Company recognizes the related reimbursable expense for which the grant is intended to compensate.</span></div> <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Functional and Presentation Currency </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">These consolidated financial statements are presented in United States dollars (“US dollars”). The functional currency of virtually all members of the Group is the U.S. dollar. The assets and liabilities of a previously held subsidiary were translated to U.S. dollars at the exchange rate prevailing on the balance sheet date and revenues and expenses were translated at the average exchange rate for the period. Foreign exchange differences resulting from the translation of this subsidiary were reported in the Consolidated Statements of Comprehensive Income/(Loss) in Other Comprehensive Income/(Loss).</span></div> Foreign Currency Transactions in foreign currencies are translated to the respective functional currencies of Group entities at the foreign exchange rate ruling at the date of the transaction. Monetary assets and liabilities denominated in foreign currencies at the balance sheet date are retranslated to the functional currency at the foreign exchange rate ruling at that date. Foreign exchange differences arising on remeasurement are recognized in the Consolidated Statement of Comprehensive Income/(Loss) except for qualifying cash flow hedges, which are recognized directly in other comprehensive income. The Company did not have qualifying cash flow hedges during the reported periods. Non-monetary assets and liabilities that are measured in terms of historical cost in a foreign currency are translated using the exchange rate at the date of the transaction. <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash and Cash Equivalents </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash and cash equivalents include all highly liquid instruments with original maturities of three months or less.</span></div> <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share Capital </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Ordinary shares are classified as equity. The Group is comprised of share capital, share premium, merger reserve, other reserve, translation reserve, and accumulated deficit.</span></div> <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Property and Equipment </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Property and equipment is stated at cost less accumulated depreciation and any accumulated impairment losses. Cost includes expenditures that are directly attributable to the acquisition of the asset. Assets under construction represent leasehold improvements and machinery and equipment to be used in operations or research and development activities. When parts of an item of property and equipment have different useful lives, they are accounted for as separate items (major components) of </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">property and equipment. Depreciation is calculated using the straight-line method over the estimated useful life of the related asset: </span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.566%"><tr><td style="width:1.0%"/><td style="width:48.900%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:48.900%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Laboratory and manufacturing equipment</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2-8 years</span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Furniture and fixtures</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7 years</span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Computer equipment and software</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1-5 years</span></div></td></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Leasehold improvements</span></td><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5-10 years, or the remaining term of the lease, if shorter</span></div></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation methods, useful lives and residual values are reviewed at each balance sheet date.</span></div> Depreciation is calculated using the straight-line method over the estimated useful life of the related asset: <div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.566%"><tr><td style="width:1.0%"/><td style="width:48.900%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:48.900%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Laboratory and manufacturing equipment</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2-8 years</span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Furniture and fixtures</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7 years</span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Computer equipment and software</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1-5 years</span></div></td></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Leasehold improvements</span></td><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5-10 years, or the remaining term of the lease, if shorter</span></div></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation methods, useful lives and residual values are reviewed at each balance sheet date.</span></div> P2Y P8Y P7Y P1Y P5Y P5Y P10Y <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Intangible Assets </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Intangible assets, which include purchased patents and licenses with finite useful lives, are carried at historical cost less accumulated amortization, if amortization has commenced, and impairment losses. Intangible assets with finite lives are amortized from the time they are available for use. Amortization is calculated using the straight-line method to allocate the costs of patents and licenses over their estimated useful lives. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development intangible assets, which are still under development and have accordingly not yet obtained marketing approval, are presented as In-Process Research and Development (IPR&amp;D). IPR&amp;D is not amortized since it is not yet available for its intended use, but it is evaluated for potential impairment on an annual basis or more frequently when facts and circumstances warrant.</span></div> <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Impairment of Non-Financial Assets </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group reviews the carrying amounts of its property and equipment and intangible assets at each reporting date to determine whether there are indicators of impairment. If any such indicators of impairment exist, then an asset’s recoverable amount is estimated. The recoverable amount is the higher of an asset’s fair value less cost of disposal and value in use.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company’s IPR&amp;D intangible assets are not yet available for their intended use. As such, they are to be tested for impairment at least annually. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">An impairment loss is recognized when an asset’s carrying amount exceeds its recoverable amount. For the purposes of impairment testing, assets are grouped at the lowest levels for which there are largely independent cash flows. If a non- financial asset instrument is impaired, an impairment loss is recognized in the Consolidated Statements of Comprehensive Income/(Loss).</span></div><div style="margin-bottom:5.25pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company did not record any impairment of such assets during the reported periods.</span></div>Investments in associates are considered impaired if, and only if, objective evidence indicates that one or more events, which occurred after the initial recognition, have had an impact on the future cash flows from the net investment and that impact can be reliably estimated. If an impairment exists the Company measures an impairment by comparing the carrying value of the net investment in the associate to its recoverable amount and recording any excess as an impairment loss. See Note 6 for impairment recorded in respect of an investment in associate during the year ended December 31, 2019. <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Employee Benefits </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Short-Term Employee Benefits </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term employee benefit obligations are measured on an undiscounted basis and expensed as the related service is provided. A liability is recognized for the amount expected to be paid if the Group has a present legal or constructive obligation due to past service provided by the employee, and the obligation can be estimated reliably.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Defined Contribution Plans </span></div>A defined contribution plan is a post-employment benefit plan under which an entity pays fixed contributions into a separate entity and has no legal or constructive obligation to pay further amounts. Obligations for contributions to defined contribution plans are recognized as an employee benefit expense in the periods during which related services are rendered by employees. Prepaid contributions are recognized as an asset to the extent that a cash refund or a reduction in future payments is available. <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Share-based Payments </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payment arrangements, in which the Group receives goods or services as consideration for its own equity instruments, are accounted for as equity-settled share-based payment transactions in accordance with IFRS 2, regardless of how the equity instruments are obtained by the Group. The grant date fair value of employee share-based payment awards is recognized as an expense with a corresponding increase in equity over the requisite service period related to the awards. The fair value is measured using an option pricing model, which takes into account the terms and conditions of the options granted. The amount recognized as an expense is adjusted to reflect the actual number of awards for which the related service and non-market performance conditions are expected to be met, such that the amount ultimately recognized as an expense is based on the number of awards that do meet the related service and non-market performance conditions at the vesting date. For share-based payment awards with market conditions, the grant date fair value is measured to reflect such conditions and there is no true-up for differences between expected and actual outcomes.</span></div> <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Development Costs </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expenditures on research activities are recognized as incurred in the Consolidated Statements of Comprehensive Income/(Loss). In accordance with IAS 38 development costs are capitalized only if the expenditure can be measured reliably, the product or process is technically and commercially feasible, future economic benefits are probable, the Group can demonstrate its ability to use or sell the intangible asset, the Group intends to and has sufficient resources to complete development and to use or sell the asset, and it is able to measure reliably the expenditure attributable to the intangible asset during its development. The point at which technical </span></div>feasibility is determined to have been reached is when regulatory approval has been received where applicable. Management determines that commercial viability has been reached when a clear market and pricing point have been identified, which may coincide with achieving meaningful recurring sales. Otherwise, the development expenditure is recognized as incurred in the Consolidated Statements of Comprehensive Income/(Loss). As of balance sheet date the Group has not capitalized any development costs. <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Provisions </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">A provision is recognized in the Consolidated Statements of Financial Position when the Group has a present legal or constructive obligation due to a past event that can be reliably measured, and it is probable that an outflow of economic benefits will be required to settle the obligation. Provisions are determined by discounting the expected future cash flows at a pre-tax rate that reflects risks specific to the liability.</span></div> <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Leases</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On January 1, 2019, the Group adopted a new accounting standard for leases. The Group leases real estate and equipment for use in operations. These leases generally have lease terms of 1 to 10 years. The Group includes options that are reasonably certain to be exercised as part of the determination of the lease term. The group determines if an arrangement is a lease at inception of the contract in accordance with guidance detailed in the new standard. ROU assets represent the Group’s right to use an underlying asset for the lease term and lease liabilities represent our obligation to make lease payments arising from the lease. Operating lease ROU assets and liabilities are recognized at commencement date based on the present value of lease payments over the lease term. As most of our leases do not provide an implicit rate, we use the Group’s estimated incremental borrowing rate based on information available at commencement date in determining the present value of future payments. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s operating leases are virtually all leases from real estate.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">When adopting IFRS 16 on January 1, 2019 , the Group has applied a modified retrospective approach by measuring the right-of-use asset at an amount equal to the lease liability at the date of transition and therefore comparative information was not restated. Upon transition, the Group has applied the following practical expedients:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">excluding initial direct costs from the right-of-use assets;</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">using hindsight when assessing the lease term; and</span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">not reassessing whether a contract is or contains a lease; </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group has elected to account for lease payments as an expense on a straight-line basis over the life of the lease for: </span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Leases with a term of 12 months or less and containing no purchase options; and </span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Leases where the underlying asset has a value of less than $5,000. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The lease liability was initially measured at the present value of the lease payments that were not paid at the transition date, discounted by using the Group's incremental borrowing rate as the rate implicit in the lease was not readily determinable.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The right-of-use asset is depreciated on a straight-line basis and the lease liability will give rise to an interest charge. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The financial impact of adopting IFRS 16 on the Group was primarily as follows:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:87.080%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.720%"/><td style="width:0.1%"/></tr><tr style="height:12pt"><td colspan="3" rowspan="2" style="padding:0 1pt"><div style="margin-bottom:6pt;text-align:justify"><span><br/></span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">January 1, 2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:12pt"><td colspan="6" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Right of use asset</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,353</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Lease liability</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,995</span></td></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Accumulated deficit</span></td><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">999 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Further information regarding the subleases, right of use asset and lease liability can be found in Note 21.</span></div> <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The financial impact of adopting IFRS 16 on the Group was primarily as follows:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:87.080%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.720%"/><td style="width:0.1%"/></tr><tr style="height:12pt"><td colspan="3" rowspan="2" style="padding:0 1pt"><div style="margin-bottom:6pt;text-align:justify"><span><br/></span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">January 1, 2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:12pt"><td colspan="6" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Right of use asset</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,353</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Lease liability</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,995</span></td></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Accumulated deficit</span></td><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">999 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> 10353000 10353000 10995000 999000 <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance Income and Finance Costs </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance income is comprised of income on funds invested in U.S. treasuries, income on money market funds and to a much lesser extent income on a finance lease. Financing income is recognized as it is earned. Finance costs comprise mainly of loan and lease liability interest expenses and the changes in the fair value of warrant and financial liabilities carried at FVTPL.</span></div> <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Taxation </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax on the profit or loss for the year comprises current and deferred income tax. In accordance with IAS 12, tax is recognized in the Consolidated Statements of Comprehensive Income/(Loss) except to the extent that it relates to items recognized directly in equity.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Current income tax is the expected tax payable or receivable on the taxable income or loss for the year, using tax rates enacted or substantially enacted at the reporting date, and any adjustment to tax payable in respect of previous years.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax is recognized due to temporary differences between the carrying amounts of assets and liabilities for financial reporting purposes and the amounts used for taxation purposes. Deferred tax assets are recognized for unused tax losses, unused tax credits and deductible temporary differences to the extent that it is probable that future taxable profits will be available against which they can be used. Deferred tax assets are reviewed at each reporting date and are reduced to the extent that it is no longer probable that the related tax benefit will be realized.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax is measured at the tax rates that are expected to be applied to temporary differences when they reverse, using tax rates enacted or substantively enacted at the reporting date.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred income tax assets and liabilities are offset when there is a legally enforceable right to offset current tax assets against current tax liabilities and when the deferred income tax assets and liabilities relate to income taxes levied by the same taxation authority on either the same taxable entity or different taxable entities where there is an intention to settle the balances on a net basis.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred taxes are recognized in Consolidated Statements of Comprehensive Income/(Loss) except to the extent that they relate to items recognized directly in equity or in other comprehensive income.</span></div> <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair Value Measurements </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s accounting policies require that certain financial and non-financial assets and certain financial liabilities be measured at their fair value.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group uses valuation techniques that are appropriate in the circumstances and for which sufficient data are available to measure fair value, maximizing the use of relevant observable inputs and minimizing the use of unobservable inputs. Fair values are categorized into different levels in a fair value hierarchy based on the inputs used in the valuation techniques as follows:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Level 1: quoted prices (unadjusted) in active markets for identical assets or liabilities.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Level 2: inputs other than quoted prices included in Level 1 that are observable for the asset or liability, either directly (i.e. as prices) or indirectly (i.e. derived from prices).</span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Level 3: inputs for the asset or liability that are not based on observable market data (unobservable inputs).</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group recognizes transfers between levels of the fair value hierarchy at the end of the reporting period during which the change has occurred.</span></div>The carrying amount of cash and cash equivalents, accounts receivable, restricted cash, deposits, accounts payable, accrued expenses and other current liabilities in the Group’s Consolidated Statements of Financial Position approximates their fair value because of the short maturities of these instruments. <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Operating Segments </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Operating segments are reported in a manner that is consistent with the internal reporting provided to the chief operating decision maker (“CODM”). The CODM reviews discrete financial information for the operating segments in order to assess their performance and is responsible for making decisions about resources allocated to the segments. The CODM has been identified as the Group’s Directors.</span></div> 14300000 New Standards and Interpretations Not Yet Adopted <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">A number of new standards, interpretations, and amendments to existing standards are effective for annual periods commencing on or after January 1, 2021 and have not been applied in preparing the consolidated financial information. The Company’s assessment of the impact of these new standards and interpretations is set out below.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Effective January 1, 2023, the definition of accounting estimates has been amended as an amendment to IAS 8 Accounting Policies, Changes in Accounting Estimates and Errors. The amendments clarify how companies should distinguish changes in accounting policies from changes in accounting estimates. The distinction is important because changes in accounting estimates are applied prospectively only to future transactions and future events, but changes in accounting policies are generally also applied retrospectively to past transactions and other past events. This amendment is not expected to have an impact on the Company's financial statements.</span></div><div style="margin-bottom:5.25pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Effective January 1, 2023, IAS 1 has been amended to clarify that liabilities are classified as either current or non-current, depending on the rights that exist at the end of the reporting period. Classification is unaffected by the expectations of the entity or events after the reporting date. The Company does not expect this amendment will have a material impact on its financial statements.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">None of the other new standards, interpretations, and amendments are applicable to the Company’s financial statements and therefore will not have an impact on the Company.</span></div> Revenue <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Revenue recorded in the Consolidated Statement of Comprehensive Income/(Loss) consists of the following:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ended December 31,</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contract revenue</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,341</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,688 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">16,371 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant income</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,427</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,119 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,377 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total revenue</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,768</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,807 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">20,748 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">All amounts recorded in contract revenue were generated in the United States.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Primarily all of the Company’s contracts as of December 31, 2020, 2019 and 2018 were determined to have a single performance obligation which consists of a combined deliverable of license to intellectual property and research and development services. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Therefore, for such contracts, revenue is recognized over time based on the inputs method which is a faithful depiction of the transfer of goods and services. Progress is measured based on costs incurred to date as compared to total projected costs. Payments for such contracts are primarily made up front at the inception of the contract (or upon achieving a milestone event) and to a much lesser extent payments are made periodically over the contract term.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the year ended December 31, 2020, the Company received a $2.0 million milestone payment from Karuna Therapeutics, Inc. following initiation of its KarXT Phase 3 clinical study pursuant to the Exclusive Patent License Agreement between PureTech and Karuna. This milestone was recognized as revenue during the year ended December 31, 2020</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Disaggregated Revenue</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group disaggregates contract revenue in a manner that depicts how the nature, amount, timing, and uncertainty of revenue and cash flows are affected by economic factors. The Group disaggregates revenue based on contract revenue or grant revenue, and further disaggregates contract revenue based on the transfer of control of the underlying performance obligations.</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Timing of contract revenue recognition</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Transferred at a point in time – Licensing Income</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,054</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">12,000 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Transferred over time</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6,286</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,688 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,371 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:0 1pt"><div style="margin-bottom:10pt"><span><br/></span></div></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,341</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,688 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">16,371 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    2020 – Attributed to Parent Company and Other; 2018 – attributed to Controlled Founded Entities segment. See note 4, Segment information.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    2020 – Attributed to Internal segment ($3,560 thousand) and Controlled founded entities segment ($2,726 thousand); 2019 – Attributed to Internal segment ($6,064 thousand), Controlled founded entities segment ($2,487 thousand) and Parent Company and Other ($137 thousand); 2018 – Attributed to Internal segment ($2,110 thousand), Controlled founded entities segment ($2,233 thousand) and Parent Company and Other ($29 thousand). See Note 4, Segment Information.</span></div><div style="margin-bottom:2pt"><span><br/></span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Customers over 10% of revenue*</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Janssen Biotech, Inc.</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">12,000 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">BMEB Services LLC</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,415 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Roche Holding AG</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,518</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,973 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Eli Lilly and Company</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">896</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,433 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Boehringer Ingelheim International GMBH</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,043</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,091 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Imbrium Therapeutics L.P.</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,736</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,013 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Karuna Therapeutics, Inc.</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,000</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,193</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,510 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,415 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">An estimation uncertainty arises due to management’s application of the inputs method in recognizing revenue overtime. In doing so, the total cost to satisfy the performance obligation includes a significant estimate by management in its budgets and projected cash flows. The sensitivity of this calculation for the years ended December 31, 2020, 2019 and 2018 is detailed below:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the year ended December 31, 2020</span></div></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Budgeted costs to complete</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">+10%</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(10)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Revenue</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(535)</span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">654</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/></tr></table></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the year ended December 31, 2019</span></div></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Budgeted costs to complete</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+10%</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Revenue</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(951)</span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">738 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the year ended December 31, 2018</span></div></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Budgeted costs to complete</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+10%</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Revenue</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(265)</span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">323 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contract Balances </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Accounts receivables represent rights to consideration in exchange for products or services that have been transferred by the Group, when payment is unconditional and only the passage of time is required before payment is due. Accounts receivables do not bear interest and are recorded at the invoiced amount. Accounts receivable are included within Trade and other receivables on the Consolidated Statement of Financial Position.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contract liabilities represent the Group’s obligation to transfer products or services to a customer for which consideration has been received, or for which an amount of consideration is due from the customer. Contract liabilities are included within deferred revenue on the Consolidated Statement of Financial Position.</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Contract Balances</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Accounts receivable</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">711</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,699 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred revenue – long term</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,220 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred revenue – short term</span></td><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,472</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,474 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the year ended December 31, 2020, $5.3 million of revenue was recognized on deferred revenue outstanding at December 31, 2019. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Remaining performance obligations represent the transaction price of unsatisfied or partially satisfied performance obligations within contracts with an original expected contract term that is greater than one year and for which fulfillment of the contract has started as of the end of the reporting period. The aggregate amount of transaction consideration allocated to remaining performance obligations as of December 31, 2020 was $1.7 million. The following table summarizes when the Group expects to recognize the remaining performance obligations as revenue. The Group will recognize revenue associated with these performance obligations as transfer of control occurs:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"><div style="margin-bottom:10pt"><span><br/></span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Less than 1 Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Greater than 1 Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Total</span></td></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Remaining Performance Obligation</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,713</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,713</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/></tr></table></div> <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Revenue recorded in the Consolidated Statement of Comprehensive Income/(Loss) consists of the following:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ended December 31,</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contract revenue</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,341</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,688 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">16,371 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant income</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,427</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,119 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,377 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total revenue</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,768</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,807 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">20,748 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">All amounts recorded in contract revenue were generated in the United States.</span></div> 8341000 8688000 16371000 3427000 1119000 4377000 11768000 9807000 20748000 2000000.0 The Group disaggregates revenue based on contract revenue or grant revenue, and further disaggregates contract revenue based on the transfer of control of the underlying performance obligations.<div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Timing of contract revenue recognition</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Transferred at a point in time – Licensing Income</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,054</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">12,000 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Transferred over time</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6,286</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,688 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,371 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:0 1pt"><div style="margin-bottom:10pt"><span><br/></span></div></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,341</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,688 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">16,371 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    2020 – Attributed to Parent Company and Other; 2018 – attributed to Controlled Founded Entities segment. See note 4, Segment information.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    2020 – Attributed to Internal segment ($3,560 thousand) and Controlled founded entities segment ($2,726 thousand); 2019 – Attributed to Internal segment ($6,064 thousand), Controlled founded entities segment ($2,487 thousand) and Parent Company and Other ($137 thousand); 2018 – Attributed to Internal segment ($2,110 thousand), Controlled founded entities segment ($2,233 thousand) and Parent Company and Other ($29 thousand). See Note 4, Segment Information.</span></div><div style="margin-bottom:2pt"><span><br/></span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Customers over 10% of revenue*</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Janssen Biotech, Inc.</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">12,000 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">BMEB Services LLC</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,415 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Roche Holding AG</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,518</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,973 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Eli Lilly and Company</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">896</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,433 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Boehringer Ingelheim International GMBH</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,043</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,091 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Imbrium Therapeutics L.P.</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,736</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,013 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Karuna Therapeutics, Inc.</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,000</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,193</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,510 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,415 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div> 2054000 0 12000000 6286000 8688000 4371000 8341000 8688000 16371000 3560000 2726000 6064000 2487000 137000 2110000 2233000 29000 0 0 12000000 0 0 1415000 1518000 4973000 0 896000 1433000 0 2043000 1091000 0 1736000 1013000 0 2000000 0 0 8193000 8510000 13415000 The sensitivity of this calculation for the years ended December 31, 2020, 2019 and 2018 is detailed below:<div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the year ended December 31, 2020</span></div></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Budgeted costs to complete</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">+10%</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(10)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Revenue</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(535)</span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">654</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/></tr></table></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the year ended December 31, 2019</span></div></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Budgeted costs to complete</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+10%</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Revenue</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(951)</span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">738 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the year ended December 31, 2018</span></div></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Budgeted costs to complete</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+10%</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Revenue</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(265)</span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">323 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> 0.10 -0.10 -535000 654000 0.10 -0.10 -951000 738000 0.10 -0.10 -265000 323000 Contract liabilities are included within deferred revenue on the Consolidated Statement of Financial Position.<table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Contract Balances</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Accounts receivable</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">711</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,699 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred revenue – long term</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,220 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred revenue – short term</span></td><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,472</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,474 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table>During the year ended December 31, 2020, $5.3 million of revenue was recognized on deferred revenue outstanding at December 31, 2019. 711000 1699000 0 1220000 1472000 5474000 5300000 1700000 The Group will recognize revenue associated with these performance obligations as transfer of control occurs:<table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"><div style="margin-bottom:10pt"><span><br/></span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Less than 1 Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Greater than 1 Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Total</span></td></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Remaining Performance Obligation</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,713</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,713</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/></tr></table> 1713000 0 1713000 Segment Information <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Basis for Segmentation </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Directors are the Group’s strategic decision-makers. The Group’s operating segments are reported based on the financial information provided to the Directors at least quarterly for the purposes of allocating resources and assessing performance. The Group has determined that each entity is representative of a single operating segment as the Directors monitor the financial results at this level. When identifying the reportable segments the Group has determined that it is appropriate to aggregate multiple operating segments into a single reportable segment given the high level of operational and financial similarities across the entities. The Group has identified four reportable segments which are outlined below. Substantially, all of the revenue and profit generating activities of the Group are generated within the U.S. and accordingly, no geographical disclosures are provided.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the year ended December 31, 2019, the Company deconsolidated three of its subsidiaries which resulted in a change to the composition of its reportable segments. The Company has revised in the 2019 financial statements the 2018 financial information to conform to the presentation as of and for the period ending December 31, 2019. The change in segments reflects how the Company’s Board of Directors reviews the Group’s results, allocates resources and assesses performance.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Internal</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Internal segment (the “Internal segment”), is advancing Wholly Owned Programs designed to harness key immunological, fibrotic and lymphatic system mechanisms. These novel classes of immunomodulatory drugs are designed to treat serious diseases, including lung dysfunction, immuno-oncology, lymphatic, neurological and neuropsychological disorders. The Internal segment is comprised of the technologies that are wholly owned and will be advanced through either PureTech Health funding or non-dilutive sources of financing in the near-term. The operational management of the Internal segment is conducted by the PureTech Health team, which is responsible for the strategy, business development, and research and development. As of December 31, 2020, this segment included PureTech LYT (formerly Ariya Therapeutics) and PureTech LYT-100.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Controlled Founded Entities</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Controlled Founded Entity segment (the “Controlled Founded Entity segment”) is comprised of the Group’s subsidiaries that are currently consolidated operational subsidiaries that either have, or have plans to hire, independent management teams and currently have already raised, or are currently in the process of raising, third-party dilutive capital. These subsidiaries have active research and development programs and either have entered into or plan to seek a strategic partnership with an equity or debt investment partner, who will provide additional industry knowledge and access to networks, as well as additional funding to continue the pursued growth of the company. As of December 31, 2020, this segment included Alivio Therapeutics, Inc., Entrega Inc., Follica Incorporated, Sonde Health Inc., and Vedanta Biosciences, Inc.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-Controlled Founded Entities</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Non-Controlled Founded Entities segment (the “Non-Controlled Founded Entities segment”) is comprised of the entities in respect of which PureTech Health (i) no longer holds majority voting control as a shareholder and no longer has the right to elect a majority of the members of the subsidiaries’ Board of Directors. Upon deconsolidation of an entity the segment disclosure is restated to reflect the change on a retrospective basis, as this constitutes a change in the composition of its reportable segments. The Non-Controlled Founded Entities segment included Akili Interactive Labs, Inc. (“Akili”), Vor Biopharma Inc. (“Vor”), Karuna Therapeutics, Inc. (“Karuna”), and Gelesis Inc. (“Gelesis”).</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Non-Controlled Founded Entities segment incorporates the operational results of the aforementioned entities to the date of deconsolidation. Following the date of deconsolidation, the Company accounts for its investment in each entity at the parent level, and therefore the results associated with investment activity following the date of deconsolidation is included in the Parent Company and Other segment (the “Parent Company and Other segment”).</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Parent Company and Other Segment </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Parent Company and Other segment includes activities that are not directly attributable to the operating segments, such as the activities of the Parent, corporate support functions and certain research and development support functions that are not directly attributable to a strategic business segment as well as the elimination of intercompany transactions. This segment also captures the accounting for the Company’s holdings in entities for which control has been lost, which is inclusive of the following items: gain on deconsolidation, gain or loss on investments held at fair value, gain on loss of significant influence, and the share of net income/ (loss) of associates accounted for using the equity method. As of December 31, 2020, this segment included PureTech Health plc, PureTech Health LLC, PureTech Management, Inc., PureTech Securities Corp. and PureTech Securities II Corp., as well as certain other dormant, inactive and shell entities.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Information About Reportable Segments: </span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:39.802%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.722%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="15" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Internal<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Controlled Founded Entities<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Non-Controlled Founded<br/>Entities<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Parent Company &amp; <br/>Other<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Consolidated<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Consolidated Statements of Comprehensive Income/(Loss)</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contract revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,560</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,726</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,054</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,341</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">32</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,395</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,427</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total revenue</span></td><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,592</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6,121</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,054</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,768</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">General and administrative expenses</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,112)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(15,061)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(32,267)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(49,440)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development expenses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(41,583)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(40,043)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(234)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(81,859)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total operating expense</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(43,695)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(55,104)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(32,500)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(131,299)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense):</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on investments held at fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">232,674</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">232,674</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Loss realized on sale of investments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(54,976)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(54,976)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on disposal of assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(15)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(15)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(30)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">965</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,065</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total other income/(expense)</span></td><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(15)</span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">85</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">178,662</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">178,732</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net finance income/(costs)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">19</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(5,204)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(930)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(6,115)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of net income/(loss) of associates accounted for using the equity method</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(34,117)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(34,117)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Income/(loss) before taxes</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(40,098)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(54,102)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">113,170</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">18,969</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000000;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Income/(loss) before taxes pre IFRS 9 fair value accounting, finance costs – subsidiary preferred shares, share-based payment expense, depreciation of tangible assets and amortization of intangible assets</span></td><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(36,770)</span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(44,181)</span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">121,644</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">40,694</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-right:1pt solid #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.19pt;font-weight:400;line-height:120%">Finance income/(costs) – subsidiary preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-right:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance income/(costs) – IFRS 9 fair value accounting</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(4,351)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(4,351)</span></td><td style="border-right:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payment expense</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,491)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,822)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(5,405)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(10,718)</span></td><td style="border-right:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation of tangible assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(838)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,560)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,547)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(3,945)</span></td><td style="border-right:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization of ROU assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,186)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,523)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,709)</span></td><td style="border-right:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization of intangible assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1)</span></td><td style="border-right:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Taxation</span></td><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1)</span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(14,400)</span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(14,401)</span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Income/(loss) for the year</span></td><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(40,098)</span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(54,103)</span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">98,769</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,568</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other comprehensive income/(loss)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">469</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">469</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total comprehensive income/(loss) for the year</span></td><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(40,098)</span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(54,103)</span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">99,238</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,037</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8pt;font-weight:700;line-height:120%">Total comprehensive income/(loss) attributable to:</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Owners of the Company</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(40,098)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(52,701)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">99,253</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6,454</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-controlling interests</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,402)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(15)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,417)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Consolidated Statements of Financial Position:</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">87,917</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">68,731</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">833,347</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">989,994</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total liabilities</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">117,964</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">212,542</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,949</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">336,455</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000000;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Net assets/(liabilities)</span></td><td colspan="2" style="border-bottom:1pt solid #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(30,047)</span></td><td style="border-bottom:1pt solid #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(143,812)</span></td><td style="border-bottom:1pt solid #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">827,397</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">653,539</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:39.802%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.722%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Internal<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Controlled Founded Entities<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Non-Controlled Founded<br/>Entities<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Parent Company &amp;<br/>Other<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Consolidated<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Consolidated Statements of Comprehensive Income/(Loss)</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contract revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,064 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,487 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">137 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,688 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,104 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,119 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total revenue</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,079 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,591 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">137 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,807 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">General and administrative expenses</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,385)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(14,436)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10,439)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(32,098)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(59,358)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development expenses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(25,977)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(42,780)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15,555)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,536)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(85,848)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total operating expense</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(28,362)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(57,216)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(25,994)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(33,634)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(145,206)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense):</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on deconsolidation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">264,409 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">264,409 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on investments held at fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(37,863)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(37,863)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on disposal of assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">17 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(39)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(60)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(82)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on loss of significant influence</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">445,582 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">445,582 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">166 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(45)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">121 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense)</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">17 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">127 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">672,023 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">672,167 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net finance income/(costs)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(16,947)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(30,141)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">941 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(46,147)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of net income/(loss) of associate accounted for using the equity method</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">30,791 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">30,791 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment of investment in associate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(42,938)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(42,938)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) before taxes </span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(22,266)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(70,445)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(56,135)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">627,320 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">478,474 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(Loss)/income before taxes pre IFRS 9 fair value accounting, finance costs – subsidiary preferred shares, share-based payment expense, depreciation of tangible assets and amortization of intangible assets</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(21,889)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(48,996)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(21,873)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">640,298 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">547,540 </span></td><td style="border-right:1pt solid #000;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.19pt;font-weight:400;line-height:120%">Finance income/(costs) – subsidiary preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">107 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,564)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,458)</span></td><td style="border-right:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance income/(costs) – IFRS 9 fair value accounting</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(17,294)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(28,737)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(444)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(46,475)</span></td><td style="border-right:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payment expense</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,678)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,543)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(9,242)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(14,468)</span></td><td style="border-right:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-left:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation of tangible assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(376)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,531)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(207)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,114)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,228)</span></td><td style="border-right:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization of ROU assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,060)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(83)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,177)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,320)</span></td><td style="border-right:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization of intangible assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(128)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(117)</span></td><td style="border-right:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Taxation</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(134)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(162)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(112,113)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(112,409)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) for the year</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(22,266)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(70,579)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(56,297)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">515,207 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">366,065 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other comprehensive income/(loss)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total comprehensive income/(loss) for the year</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(22,266)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(70,579)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(56,307)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">515,207 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">366,055 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total comprehensive income/(loss) attributable to:</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Owners of the Company</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(7,002)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(54,717)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(32,353)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">515,207 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">421,133 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-controlling interests</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15,264)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15,862)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(23,953)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(55,079)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Consolidated Statements of Financial Position:</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">17,614 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41,612 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">881,952 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">941,178 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total liabilities</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">12,076 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">132,935 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">145,768 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">290,779 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net (liabilities)/assets</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,538 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(91,324)</span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">736,184 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">650,399 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:39.802%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.722%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Internal<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Controlled Founded Entities<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Non-Controlled Founded<br/>Entities<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Parent Company &amp;<br/>Other<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Consolidated<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Consolidated Statements of Comprehensive Loss</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contract revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,110 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,233 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">29 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">16,371 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,271 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">20 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,377 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total revenue</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,195 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">18,504 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">20 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">29 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">20,748 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">General and administrative expenses</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,498)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10,212)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(16,385)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(19,270)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(47,365)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development expenses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,929)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(36,930)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(29,851)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,692)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(77,402)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total operating expense</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10,427)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(47,142)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(46,236)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(20,962)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(124,768)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense):</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on deconsolidation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41,730 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41,730 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on investments held at fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(34,615)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(34,615)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on disposal of assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,054 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,054 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on loss of significant influence</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,287 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,287 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">104 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(405)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(302)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense)</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">104 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">21,051 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">21,155 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net finance income/(costs)</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,341 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,945 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,631 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">25,918 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of net income/(loss) of associate accounted for using the equity method</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(11,490)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(11,490)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) before taxes</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,232)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(23,297)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(40,167)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,258 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(68,438)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(Loss)/income before taxes pre IAS 39 fair value accounting, finance costs – subsidiary preferred shares, share-based payment expense, depreciation of tangible assets and amortization of intangible assets</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,210)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(24,344)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(38,761)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,235)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(75,550)</span></td><td style="border-right:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.19pt;font-weight:400;line-height:120%">Finance income/(costs) – subsidiary preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(106)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(106)</span></td><td style="border-right:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance income/(costs) – IAS 39 fair value accounting</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,341 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,516 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,775 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22,632 </span></td><td style="border-right:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payment expense</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(11)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,465)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,262)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,899)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(12,637)</span></td><td style="border-right:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-left:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation of tangible assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(7)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,823)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(390)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(256)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,476)</span></td><td style="border-right:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization of intangible assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(270)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(22)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(302)</span></td><td style="border-right:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Taxation</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(381)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(185)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,655)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,221)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) for the year</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,454)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(26,206)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(41,239)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,239 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(70,659)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other comprehensive income/(loss)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(214)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(26)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(240)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total comprehensive income/(loss) for the year</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,454)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(26,420)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(41,239)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,213 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(70,899)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total comprehensive income/(loss) attributable to:</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Owners of the Company</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,139)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15,710)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(32,260)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,213 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(43,894)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-controlling interests</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(7,315)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10,710)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,980)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(27,005)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Consolidated Statements of Financial Position:</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,984 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15,603 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">35,934 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">387,240 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">441,761 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total liabilities</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,366 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">60,992 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">202,161 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,731)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">274,787 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net (liabilities)/assets</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10,381)</span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(45,389)</span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(166,227)</span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">388,970 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">166,973 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table>The proportion of net assets shown above that is attributable to non-controlling interest is disclosed in Note 18. <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Information About Reportable Segments: </span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:39.802%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.722%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="15" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Internal<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Controlled Founded Entities<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Non-Controlled Founded<br/>Entities<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Parent Company &amp; <br/>Other<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Consolidated<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Consolidated Statements of Comprehensive Income/(Loss)</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contract revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,560</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,726</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,054</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,341</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">32</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,395</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,427</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total revenue</span></td><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,592</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6,121</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,054</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,768</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">General and administrative expenses</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,112)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(15,061)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(32,267)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(49,440)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development expenses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(41,583)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(40,043)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(234)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(81,859)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total operating expense</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(43,695)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(55,104)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(32,500)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(131,299)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense):</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on investments held at fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">232,674</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">232,674</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Loss realized on sale of investments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(54,976)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(54,976)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on disposal of assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(15)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(15)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(30)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">965</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,065</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total other income/(expense)</span></td><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(15)</span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">85</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">178,662</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">178,732</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net finance income/(costs)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">19</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(5,204)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(930)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(6,115)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of net income/(loss) of associates accounted for using the equity method</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(34,117)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(34,117)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Income/(loss) before taxes</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(40,098)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(54,102)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">113,170</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">18,969</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000000;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Income/(loss) before taxes pre IFRS 9 fair value accounting, finance costs – subsidiary preferred shares, share-based payment expense, depreciation of tangible assets and amortization of intangible assets</span></td><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(36,770)</span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(44,181)</span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">121,644</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">40,694</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-right:1pt solid #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.19pt;font-weight:400;line-height:120%">Finance income/(costs) – subsidiary preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-right:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance income/(costs) – IFRS 9 fair value accounting</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(4,351)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(4,351)</span></td><td style="border-right:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payment expense</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,491)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,822)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(5,405)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(10,718)</span></td><td style="border-right:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation of tangible assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(838)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,560)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,547)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(3,945)</span></td><td style="border-right:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization of ROU assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,186)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,523)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,709)</span></td><td style="border-right:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization of intangible assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1)</span></td><td style="border-right:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Taxation</span></td><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1)</span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(14,400)</span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(14,401)</span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Income/(loss) for the year</span></td><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(40,098)</span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(54,103)</span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">98,769</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,568</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other comprehensive income/(loss)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">469</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">469</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total comprehensive income/(loss) for the year</span></td><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(40,098)</span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(54,103)</span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">99,238</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,037</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8pt;font-weight:700;line-height:120%">Total comprehensive income/(loss) attributable to:</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Owners of the Company</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(40,098)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(52,701)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">99,253</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6,454</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-controlling interests</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,402)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(15)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,417)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Consolidated Statements of Financial Position:</span></td><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">87,917</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">68,731</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">833,347</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">989,994</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total liabilities</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">117,964</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">212,542</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,949</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">336,455</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000000;border-top:1pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Net assets/(liabilities)</span></td><td colspan="2" style="border-bottom:1pt solid #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(30,047)</span></td><td style="border-bottom:1pt solid #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(143,812)</span></td><td style="border-bottom:1pt solid #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">827,397</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000000;border-top:1pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">653,539</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000000;border-top:1pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:39.802%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.722%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Internal<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Controlled Founded Entities<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Non-Controlled Founded<br/>Entities<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Parent Company &amp;<br/>Other<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Consolidated<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Consolidated Statements of Comprehensive Income/(Loss)</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contract revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,064 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,487 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">137 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,688 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,104 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,119 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total revenue</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,079 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,591 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">137 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,807 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">General and administrative expenses</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,385)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(14,436)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10,439)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(32,098)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(59,358)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development expenses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(25,977)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(42,780)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15,555)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,536)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(85,848)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total operating expense</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(28,362)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(57,216)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(25,994)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(33,634)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(145,206)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense):</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on deconsolidation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">264,409 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">264,409 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on investments held at fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(37,863)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(37,863)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on disposal of assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">17 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(39)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(60)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(82)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on loss of significant influence</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">445,582 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">445,582 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">166 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(45)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">121 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense)</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">17 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">127 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">672,023 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">672,167 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net finance income/(costs)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(16,947)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(30,141)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">941 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(46,147)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of net income/(loss) of associate accounted for using the equity method</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">30,791 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">30,791 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment of investment in associate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(42,938)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(42,938)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) before taxes </span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(22,266)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(70,445)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(56,135)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">627,320 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">478,474 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(Loss)/income before taxes pre IFRS 9 fair value accounting, finance costs – subsidiary preferred shares, share-based payment expense, depreciation of tangible assets and amortization of intangible assets</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(21,889)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(48,996)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(21,873)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">640,298 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">547,540 </span></td><td style="border-right:1pt solid #000;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.19pt;font-weight:400;line-height:120%">Finance income/(costs) – subsidiary preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">107 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,564)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,458)</span></td><td style="border-right:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance income/(costs) – IFRS 9 fair value accounting</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(17,294)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(28,737)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(444)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(46,475)</span></td><td style="border-right:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payment expense</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,678)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,543)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(9,242)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(14,468)</span></td><td style="border-right:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-left:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation of tangible assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(376)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,531)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(207)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,114)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,228)</span></td><td style="border-right:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization of ROU assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,060)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(83)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,177)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,320)</span></td><td style="border-right:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization of intangible assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(128)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(117)</span></td><td style="border-right:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Taxation</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(134)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(162)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(112,113)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(112,409)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) for the year</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(22,266)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(70,579)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(56,297)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">515,207 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">366,065 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other comprehensive income/(loss)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total comprehensive income/(loss) for the year</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(22,266)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(70,579)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(56,307)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">515,207 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">366,055 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total comprehensive income/(loss) attributable to:</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Owners of the Company</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(7,002)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(54,717)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(32,353)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">515,207 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">421,133 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-controlling interests</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15,264)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15,862)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(23,953)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(55,079)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Consolidated Statements of Financial Position:</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">17,614 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41,612 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">881,952 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">941,178 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total liabilities</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">12,076 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">132,935 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">145,768 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">290,779 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net (liabilities)/assets</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,538 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(91,324)</span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">736,184 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">650,399 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:39.802%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.722%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Internal<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Controlled Founded Entities<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Non-Controlled Founded<br/>Entities<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Parent Company &amp;<br/>Other<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Consolidated<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Consolidated Statements of Comprehensive Loss</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contract revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,110 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,233 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">29 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">16,371 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,271 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">20 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,377 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total revenue</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,195 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">18,504 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">20 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">29 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">20,748 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">General and administrative expenses</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,498)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10,212)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(16,385)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(19,270)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(47,365)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development expenses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,929)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(36,930)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(29,851)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,692)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(77,402)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total operating expense</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10,427)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(47,142)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(46,236)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(20,962)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(124,768)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense):</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on deconsolidation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41,730 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41,730 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on investments held at fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(34,615)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(34,615)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on disposal of assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,054 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,054 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on loss of significant influence</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,287 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,287 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">104 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(405)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(302)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense)</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">104 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">21,051 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">21,155 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net finance income/(costs)</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,341 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,945 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,631 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">25,918 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of net income/(loss) of associate accounted for using the equity method</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(11,490)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(11,490)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) before taxes</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,232)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(23,297)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(40,167)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,258 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(68,438)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(Loss)/income before taxes pre IAS 39 fair value accounting, finance costs – subsidiary preferred shares, share-based payment expense, depreciation of tangible assets and amortization of intangible assets</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,210)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(24,344)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(38,761)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,235)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(75,550)</span></td><td style="border-right:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.19pt;font-weight:400;line-height:120%">Finance income/(costs) – subsidiary preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(106)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(106)</span></td><td style="border-right:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance income/(costs) – IAS 39 fair value accounting</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,341 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,516 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,775 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22,632 </span></td><td style="border-right:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payment expense</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(11)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,465)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,262)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,899)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(12,637)</span></td><td style="border-right:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-left:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation of tangible assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(7)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,823)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(390)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(256)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,476)</span></td><td style="border-right:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization of intangible assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(270)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(22)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(302)</span></td><td style="border-right:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Taxation</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(381)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(185)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,655)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,221)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) for the year</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,454)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(26,206)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(41,239)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,239 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(70,659)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other comprehensive income/(loss)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(214)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(26)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(240)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total comprehensive income/(loss) for the year</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,454)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(26,420)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(41,239)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,213 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(70,899)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total comprehensive income/(loss) attributable to:</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Owners of the Company</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,139)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15,710)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(32,260)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,213 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(43,894)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-controlling interests</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(7,315)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10,710)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,980)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(27,005)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Consolidated Statements of Financial Position:</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,984 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15,603 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">35,934 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">387,240 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">441,761 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total liabilities</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,366 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">60,992 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">202,161 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,731)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">274,787 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net (liabilities)/assets</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10,381)</span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(45,389)</span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(166,227)</span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">388,970 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">166,973 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table> 3560000 2726000 0 2054000 8341000 32000 3395000 0 0 3427000 3592000 6121000 0 2054000 11768000 -2112000 -15061000 0 -32267000 -49440000 -41583000 -40043000 0 -234000 -81859000 -43695000 -55104000 0 -32500000 -131299000 0 0 0 232674000 232674000 0 0 0 54976000 54976000 -15000 -15000 0 0 -30000 0 100000 0 965000 1065000 -15000 85000 0 178662000 178732000 19000 -5204000 0 -930000 -6115000 0 0 0 -34117000 -34117000 -40098000 -54102000 0 113170000 18969000 -36770000 -44181000 0 121644000 40694000 0 0 0 0 0 0 -4351000 0 0 -4351000 -2491000 -2822000 0 -5405000 -10718000 -838000 -1560000 0 -1547000 -3945000 0 -1186000 0 -1523000 -2709000 0 -1000 0 0 -1000 0 1000 0 14400000 14401000 -40098000 -54103000 0 98769000 4568000 0 0 0 469000 469000 -40098000 -54103000 0 99238000 5037000 -40098000 -52701000 0 99253000 6454000 0 -1402000 0 -15000 -1417000 87917000 68731000 0 833347000 989994000 117964000 212542000 0 5949000 336455000 -30047000 -143812000 0 827397000 653539000 6064000 2487000 0 137000 8688000 15000 1104000 0 0 1119000 6079000 3591000 0 137000 9807000 -2385000 -14436000 -10439000 -32098000 -59358000 -25977000 -42780000 -15555000 -1536000 -85848000 -28362000 -57216000 -25994000 -33634000 -145206000 0 0 0 264409000 264409000 0 0 0 -37863000 -37863000 17000 -39000 0 -60000 -82000 0 0 0 445582000 445582000 0 166000 0 -45000 121000 17000 127000 0 672023000 672167000 0 -16947000 -30141000 941000 -46147000 0 0 0 30791000 30791000 0 0 0 -42938000 -42938000 -22266000 -70445000 -56135000 627320000 478474000 -21889000 -48996000 -21873000 640298000 547540000 0 107000 -1564000 -1000 -1458000 0 -17294000 -28737000 -444000 -46475000 -5000 -1678000 -3543000 -9242000 -14468000 -376000 -1531000 -207000 -1114000 -3228000 0 -1060000 -83000 -2177000 -3320000 4000 7000 -128000 0 -117000 0 134000 162000 112113000 112409000 -22266000 -70579000 -56297000 515207000 366065000 0 0 -10000 0 -10000 -22266000 -70579000 -56307000 515207000 366055000 -7002000 -54717000 -32353000 515207000 421133000 -15264000 -15862000 -23953000 0 -55079000 17614000 41612000 0 881952000 941178000 12076000 132935000 0 145768000 290779000 5538000 -91324000 0 736184000 650399000 2110000 14233000 0 29000 16371000 86000 4271000 20000 0 4377000 2195000 18504000 20000 29000 20748000 -1498000 -10212000 -16385000 -19270000 -47365000 -8929000 -36930000 -29851000 -1692000 -77402000 -10427000 -47142000 -46236000 -20962000 -124768000 0 0 0 41730000 41730000 0 0 0 -34615000 -34615000 0 0 0 4054000 4054000 0 0 0 10287000 10287000 0 104000 -405000 -302000 0 0 104000 21051000 21155000 5341000 5945000 14631000 25918000 0 0 0 -11490000 -11490000 -8232000 -23297000 -40167000 3258000 -68438000 -8210000 -24344000 -38761000 -4235000 -75550000 0 0 0 -106000 -106000 0 5341000 5516000 11775000 22632000 -11000 -2465000 -6262000 -3899000 -12637000 -7000 -1823000 -390000 -256000 -2476000 -4000 -6000 -270000 -22000 -302000 0 381000 185000 1655000 2221000 -8454000 -26206000 -41239000 5239000 -70659000 0 -214000 0 -26000 -240000 -8454000 -26420000 -41239000 5213000 -70899000 -1139000 -15710000 -32260000 5213000 -43894000 -7315000 -10710000 -8980000 0 -27005000 2984000 15603000 35934000 387240000 441761000 13366000 60992000 202161000 -1731000 274787000 -10381000 -45389000 -166227000 388970000 166973000 Investments held at fair value<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investments held at fair value include both unlisted and listed securities held by PureTech. These investments, which include Akili, Vor, Karuna, Gelesis (other than the investment in common shares – please refer to Note 6), resTORbio and other insignificant investments, are initially measured at fair value and are subsequently re-measured at fair value at each reporting date. Interests in these investments were accounted for as shown below:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:87.080%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.720%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Investments held at fair value</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000's</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of January 1, 2019</span></div></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">169,755 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiaries (Vor, Karuna and Gelesis (Note 6))</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">138,571 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassification of Karuna investment to investment in associate </span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(118,006)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on Karuna investment at initial public offering</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">40,633 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash purchase of Gelesis convertible notes (please refer to Note 6)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,480 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash purchase of Gelesis preferred shares (please refer to Note 6)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,020 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassification of Karuna investment at loss of significant influence</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">557,243 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sale of resTORbio shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(9,295)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Loss – fair value through profit and loss</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(78,496)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2019 and January 1, 2020</span></div></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">714,905 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sale of Karuna shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(347,538)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sale of resTORbio shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,048)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Loss realised on sale of investments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(54,976)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash purchase of Gelesis preferred shares (please refer to Note 6)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash purchase of Vor preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,150 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) – fair value through profit and loss</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">232,674 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2020 before allocation of share in associate loss to long-term interest</span></div></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">553,167</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of associate loss allocated to long-term interest (please refer to Note 6)</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(23,006)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2020 after allocation of share in associate loss to long-term interest</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:5.52pt;font-weight:700;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">530,161</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    The net amount of these two items is a loss of $37.9 million which is reported on the line Gain/(loss) on investments held at fair value in the Consolidated Statements of Comprehensive Income/(Loss).</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Fair value of investments accounted for at fair value, does not take into consideration contribution from milestones that occurred after December 31, 2020, the value of the Group's consolidated Founded Entities (Vedanta, Follica, Sonde, Akili, Alivio, and Entrega), the Internal segment, or cash and cash equivalents.</span></div><div style="margin-bottom:2pt"><span><br/></span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vor</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vor was founded by PureTech through an initial Series A-1 Preferred Shares financing and raised funds through issuance of convertible notes. As of December 31, 2018, PureTech maintained control of Vor and the subsidiary’s financial results were fully consolidated in the Group’s consolidated financial statements. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On February 12, 2019, Vor completed a Series A-2 Preferred Shares financing round with PureTech and several new third party investors. The financing provided for the purchase of 62,819,866 shares of Vor Series A-2 Preferred Shares at the purchase price of $0.40 per share.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As a result of the issuance of Series A-2 preferred shares to third-party investors, PureTech’s ownership percentage and corresponding voting rights dropped from 79.5 percent to 47.5 percent, and PureTech simultaneously gave up control on Vor’s Board of Directors, both of which triggered a loss of control over the entity. As of February 12, 2019, Vor was deconsolidated from the Group’s financial statements, resulting in only the profits and losses generated by Vor through the deconsolidation date being included in the Consolidated Statement of Comprehensive Income/(Loss). While the Company no longer controlled Vor, it was concluded that PureTech still had significant influence over Vor by virtue of its large, albeit minority, ownership stake and its continued representation on Vor’s Board of Directors. During the year ended December 31, 2019, the Company recognized a $6.4 million gain on the deconsolidation of Vor, which was recorded to the Gain on the deconsolidation of subsidiary line item in the Consolidated Statement of Comprehensive Income/(Loss).</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As PureTech did not hold common shares in Vor upon deconsolidation and the preferred shares it holds do not have equity-like features, the voting percentage attributable to common shares is nil. Therefore, PureTech had no basis to account for its investment in Vor under IAS 28. The preferred shares held by PureTech fall under the guidance of IFRS 9 and are treated as a financial asset held at fair value through the Consolidated Statement of Comprehensive Income/(Loss). The fair value of the preferred shares at deconsolidation was $12.0 million.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the year ended December 31, 2019, the Company recognized a gain of $0.6 million that was recorded on the line item Gain/(loss) on investments held at fair value within the Consolidated Statement of Comprehensive Income/(Loss). Please refer to Note 16 for information regarding the valuation of these instruments.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On February 12, 2020, PureTech participated in the second closing of Vor’s Series A-2 Preferred Share financing. For consideration of $0.7 million, PureTech received 1,625,000 A-2 shares. On June 30, 2020, PureTech participated in the first closing of Vor’s Series B Preferred Share financing. For consideration of $0.5 million, PureTech received 961,538 shares. Upon the conclusion of such Vor financings PureTech no longer has significant influence over Vor. During the year ended December 31, 2020 PureTech recognized a fair value gain of $19.1 million in respect of its investment in Vor that was recorded in the line item Gain/(loss) on investments </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">held at fair value within the Consolidated Statement of Comprehensive Income/(Loss). Please refer to Note 16 for information regarding the valuation of these instruments.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of July 1, 2019, Gelesis was deconsolidated from the Group’s financial statements, resulting in only the profits and losses generated by Gelesis through the deconsolidation date being included in the Group’s Consolidated Statement of Income/(Loss). At the date of deconsolidation, PureTech recorded a $156.0 million gain on the deconsolidation of Gelesis, which was recorded to the Gain on the deconsolidation of subsidiary line item in the Consolidated Statement of Income/(Loss). The preferred shares and warrants held by PureTech fall under the guidance of IFRS 9 and are treated as financial assets held at fair value, where changes to the fair value of the preferred shares and warrant are recorded through the Consolidated Statement of Income/(Loss). The fair value of the preferred shares and warrants at deconsolidation was $49.2 million. Please refer to Note 6 for information regarding the Company's investment in Gelesis as an associate. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On August 12, 2019, Gelesis issued a convertible promissory note to the Company in the amount of $2.0 million. On October 7, 2019, Gelesis issued an amended and restated convertible note (the “Gelesis Note”) to the Company in the principal amount of up to $6.5 million. The Gelesis Note was payable in installments, with $2.0 million of the note drawn down upon execution of the original note in August 2019 and an additional $3.3 million and $1.2 million drawn down on October 7, 2019 and November 5, 2019, respectively. The Gelesis Note was convertible upon the occurrence of Gelesis’ next qualified equity financing, or at the demand of the Company at any date after December 31, 2019. The Gelesis Note fell under the guidance of IFRS 9 and was treated as a financial asset held at fair with all movements to the value of the note recorded through the Consolidated Statement of Income/(Loss).</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On December 5, 2019, Gelesis closed its Series 3 Growth Preferred Stock financing, at which point all outstanding principal and interest under the Gelesis Note converted into shares of Series 3 Growth Preferred Stock. In addition to the shares issued upon conversion of the Gelesis Note, PureTech purchased $8.0 million of Series 3 Growth Preferred Stock in the December financing. On April 1, 2020, PureTech participated in the 2nd closing of Gelesis’s Series 3 Growth Preferred Share financing. For consideration of $10.0 million, PureTech received 579,038 Series 3 Growth shares.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the years ended December 31, 2020 and 2019, the Company recognized in respect of the investments in Gelesis held at fair value a gain of $7.1 million and a loss of $18.7 million, respectively, that were recorded in the line item Gain/(loss) on investments held at fair value within the Consolidated Statements of Comprehensive Income/(Loss). The loss recorded in 2019 was primarily as a result of the Gelesis Series 3 Growth financing, which was executed with terms that resulted in a decrease in fair value across all other classes of preferred shares. Additionally, due to the equity method based investment in Gelesis being reduced to zero, the Company allocated a portion of its share in the net loss in Gelesis for the year ended December 31, 2020, totaling $23.0 million, to its preferred share investments in Gelesis, which are considered to be long-term interests in Gelesis . Please refer to Note 16 for information regarding the valuation of these instruments.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Karuna</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Karuna was founded by PureTech and raised funding through Preferred Share financings as well as convertible note issuances. As of December 31, 2018, PureTech maintained control of Karuna and Karuna's financial statements were fully consolidated in the Group’s consolidated financial statements. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On March 15, 2019, Karuna completed the closing of a Series B Preferred Share financing with PureTech and several new third party investors. The financing provided for the purchase of 5,285,102 shares of Karuna Series B Preferred Shares at a purchase price of $15.14 per share. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As a result of the issuance of the preferred shares to third-party investors, PureTech’s ownership percentage and corresponding voting rights related to Karuna dropped from 70.9 percent to 44.3 percent, and PureTech simultaneously lost control over Karuna’s Board of Directors, both of which triggered a loss of control over the entity. As of March 15, 2019, Karuna was deconsolidated from the Group’s financial statements, resulting in only the profits and losses generated by Karuna through the deconsolidation date being included in the Group’s Consolidated Statement of Comprehensive Income/(Loss). At the date of deconsolidation, PureTech recorded a $102.0 million gain on the deconsolidation of Karuna, which was recorded to the Gain on the deconsolidation of subsidiary line item in the Consolidated Statement of Comprehensive Income/(Loss). While the Company no longer controls Karuna, it was concluded that PureTech still had significant influence over Karuna by virtue of its large, albeit minority, ownership stake and its continued representation on Karuna’s Board of Directors. PureTech still had the power to participate in the financial and operating policy decisions of the entity, although it did not control these policies. As PureTech had significant influence over Karuna, the entity was accounted for as an associate under IAS 28.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Upon the date of deconsolidation, PureTech held both preferred and common shares in Karuna and a warrant issued by Karuna to PureTech. The preferred shares and warrant held by PureTech fell under the guidance of IFRS 9 and were treated as financial assets held at fair value, and all movements to the value of preferred shares held by PureTech were recorded through the Consolidated Statement of Comprehensive Income/(Loss), in accordance with IFRS 9. The fair value of the preferred shares and warrant at deconsolidation was $72.4 million. Subsequent to deconsolidation, PureTech purchased an additional $5.0 million of Karuna Series B Preferred shares.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Due to the immaterial investment in common shares and overwhelmingly large losses by Karuna, the common share investment accounted for under the equity method was remeasured to nil immediately following both the deconsolidation and the exercise of the warrant in the first half of 2019.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On June 28, 2019, Karuna priced its IPO. PureTech’s ownership percentage and corresponding voting rights related to Karuna dropped from 44.3 percent percent to 31.6 percent; however, PureTech retained significant influence due to its continued </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">presence on the board and its large, albeit minority, equity stake in the company. Upon completion of the IPO, the Karuna preferred shares held by PureTech converted to common shares. In light of PureTech’s common share holdings in Karuna and corresponding voting rights, PureTech had re-established a basis to account for its investment in Karuna under IAS 28. The preferred shares investment held at fair value was therefore reclassified to investment in associate upon completion of the conversion. During the year ended December 31, 2019 and up to June 28, 2019, the Company recognized a gain of $40.6 million that was recorded on the line item Gain on investments held at fair value within the Consolidated Statement of Comprehensive Income/(Loss) related to the preferred shares that increased in value between the date of deconsolidation and the date of Karuna’s IPO. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of December 2, 2019 it was concluded that the Company no longer exerted significant influence over Karuna owing to the resignation of the PureTech designee from Karuna’s board of directors, with PureTech retaining no ability to reappoint representation. Furthermore, PureTech is not involved in any manner, or has any influence, on the management of Karuna, or on any of its decision making processes and has no ability to do so. As such, PureTech lost the power to participate in the financial and operating policy decisions of Karuna. As a result, Karuna is no longer deemed an Associate and does not meet the scope of equity method accounting, resulting in the investment being accounted for as an investment held at fair value. As of December 2, 2019 the Company's interest in Karuna was 28.4 percent. For the period of June 28, 2019 through December 2, 2019, PureTech’s investment in Karuna was subject to equity method accounting. In accordance with IAS 28, the Company’s investment was adjusted by the share of losses generated by Karuna (weighted average of 31.4 percent based on common stock ownership interest), which resulted in a net loss of associates accounted for using the equity method of $6.3 million during the year ended December 31, 2019. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Upon PureTech’s loss of significant influence, the investment in Karuna was reclassified to an investment held at fair value. This change led PureTech to recognize a gain on loss of significant influence of $445.6 million that was recorded to the Consolidated Statement of Comprehensive Income/(Loss) on the line item Gain on loss of significant influence during the year ended December 31, 2019. The investment in Karuna after the recording of the gain on loss of significant influence was $557.2 million, which was reclassified from Investments in associates to Investments held at fair value. Additionally, from December 2, 2019 PureTech recorded a $0.7 million loss on the line item Gain/(loss) on investments held at fair value within the Consolidated Statement of Comprehensive Income/(Loss) for the year ended December 31, 2019.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On January 22, 2020, PureTech sold 2,100,000 shares of Karuna common shares for aggregate proceeds of $200.9 million. On May 26, 2020, PureTech sold an additional 555,500 Karuna common shares for aggregate proceeds of $45.0 million. On August 26, 2020, PureTech sold 1,333,333 common shares of Karuna for aggregate proceeds of $101.6 million. As a result of the sales, Puretech recorded a loss of $54.8 million attributable to blockage discount included in the sales price, to the line item Loss Realized on Sale of Investment within the Consolidated Statement of Comprehensive Income/(Loss). Additionally, during the year ended December 31, 2020 PureTech recognized a fair value gain of $191.2 million in respect of its investment in Karuna that was recorded in the line item Gain/(loss) on investments held at fair value within the Consolidated Statement of Comprehensive Income/(Loss). As of December 31, 2020 PureTech held a 12.6 percent interest in Karuna. Please refer to Note 16 for information regarding the valuation of these instruments.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Akili</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On May 8, 2018, Akili completed the first closing of a Series C Preferred Stock financing in which PureTech Health did not invest. As a result of the issuance of the preferred shares to third-party investors, following the first close of the Series C financing, PureTech’s ownership percentage and corresponding voting rights related to Akili dropped from 61.8 percent to 41.9 percent, triggering a loss of control over the entity. As of May 2018, Akili was deconsolidated from the Group’s financial statements, resulting in only the profits and losses generated by Akili through May 2018 being included in the Group’s Consolidated Statements of Comprehensive Income/(Loss). As a result of the deconsolidation, PureTech recognized a $41.7 million gain on the deconsolidation during the year ended December 31, 2018, which was recorded to the Consolidated Statement of Comprehensive Income/(Loss) on the line item Gain on the deconsolidation of subsidiary.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As PureTech did not hold common shares in Akili upon deconsolidation and the preferred shares it holds do not have equity-like features, the voting percentage attributable to common shares is nil. Therefore, PureTech had no basis to account for its investment in Akili under IAS 28. The preferred shares held by PureTech Health fall under the guidance of IFRS 9 and are treated as a financial asset held at fair value and all movements to the value of the preferred shares is recorded through the Consolidated Statements of Comprehensive Income/(Loss), in accordance with IFRS 9. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the years ended December 31, 2020 and 2019, the Company recognized a gain of $14.4 million and $11.5 million, respectively, that was recorded in the line item Gain/(loss) on investments held at fair value within the Consolidated Statements of Comprehensive Income/(Loss) in respect of PureTech's investment in Akili. Please refer to Note 16 for information regarding the valuation of these instruments.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">resTORbio</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On January 26, 2018, resTORbio, Inc., closed its initial public offering. Prior to the resTORbio IPO, PureTech Health recorded a loss of $14.3 million during the year ended December 31, 2018 to the Consolidated Statement of Comprehensive Income/(Loss) within Gain/(Loss) on investments held at Fair Value to adjust the fair value related to its resTORbio Series A Preferred Share investment. Upon completion of the public offering, the resTORbio Series A Preferred Shares held by PureTech Health converted to common shares. In light of PureTech’s common shares holdings in resTORbio and corresponding voting rights, the preferred shares investment held at fair value was reclassified to investment in associate upon the completion of the conversion.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For the period of January 1, 2018 through November 5, 2018, PureTech’s investment in resTORbio was subject to equity method accounting. In accordance with IAS 28, PureTech’s investment was adjusted by the share of profits and losses generated by </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">resTORbio (34.9 percent based on common stock ownership interest) in that period, which resulted in a net loss from associates of $11.5 million recorded to the Consolidated Statement of Comprehensive Income/(Loss) in the line item Share of net loss of associates during the year ended December 31, 2018.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of November 6, 2018, it was that concluded the Company no longer exerted significant influence over resTORbio, as PureTech lost the power to participate in the financial and operating policy decisions of resTORbio. As a result, resTORbio was no longer deemed an Associate and did not meet the scope of equity method accounting, resulting in the investment being accounted for as an investment held at fair value. This change led PureTech to recognize a gain on loss of significant influence of $10.3 million that was recorded to the Consolidated Statement of Comprehensive Income/(Loss) on the line item Gain on loss of significant influence during the year ended December 31, 2018. Additionally, PureTech recorded a loss of $33.0 million for the adjustment to fair value in connection with its investment in resTORbio to the Consolidated Statement of Comprehensive Income/(Loss) on the line item Gain/(loss) on investments held at fair value during the year ended December 31, 2018.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On November 15, 2019, resTORbio announced that top line data from the Protector 1 Phase 3 study evaluating the safety and efficacy of RTB101 in preventing clinically symptomatic respiratory illness in adults age 65 and older, did not meet its primary endpoint and the Company has stopped the development of RTB101 in this indication. As a result of ceasing the development of RTB101, resTORbio’s share price witnessed a decline in price. In November and December 2019, PureTech Health sold 7,680,700 common shares of resTORbio for aggregate proceeds of $9.3 million. Immediately following the sale of common shares, PureTech Health held 2,119,696 common shares, or 5.8 percent, of resTORbio. During the year ended December 31, 2019 PureTech recorded a loss of $71.9 million for the adjustment to fair value of its investment in resTORbio to the Consolidated Statement of Comprehensive Income/(Loss) in the line item Gain/(loss) on investments held at fair value.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On April 30, 2020, PureTech sold its remaining 2,119,696 resTORbio common shares, for aggregate proceeds of $3.0 million. As a result of the sale, the Company recorded a loss of $0.2 million attributable to blockage discount included in the sales price, to the line item Loss realized on sale of investments within the Consolidated Statement of Comprehensive Income/(Loss). Additionally, during the year ended December 31, 2020, the Company recognized a gain of $0.1 million that was recorded on the line item Gain/(loss) on investments held at fair value within the Consolidated Statement of Comprehensive Income/(Loss). Please refer to Note 16 for information regarding the valuation of these instruments.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on deconsolidation</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes the gain on deconsolidation recognized by the Company:</span></div><div style="margin-bottom:5.25pt;text-align:justify"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Year ended December 31,</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on deconsolidation of Akili</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41,730 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on deconsolidation of Vor</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,357 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on deconsolidation of Karuna</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">102,038 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on deconsolidation of Gelesis [Note 6]</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">156,014 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total gain on deconsolidation</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">264,409 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41,730 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> Interests in these investments were accounted for as shown below:<div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:87.080%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.720%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Investments held at fair value</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000's</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of January 1, 2019</span></div></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">169,755 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiaries (Vor, Karuna and Gelesis (Note 6))</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">138,571 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassification of Karuna investment to investment in associate </span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(118,006)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on Karuna investment at initial public offering</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">40,633 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash purchase of Gelesis convertible notes (please refer to Note 6)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,480 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash purchase of Gelesis preferred shares (please refer to Note 6)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,020 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassification of Karuna investment at loss of significant influence</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">557,243 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sale of resTORbio shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(9,295)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Loss – fair value through profit and loss</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(78,496)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2019 and January 1, 2020</span></div></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">714,905 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sale of Karuna shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(347,538)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sale of resTORbio shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,048)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Loss realised on sale of investments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(54,976)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash purchase of Gelesis preferred shares (please refer to Note 6)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash purchase of Vor preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,150 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) – fair value through profit and loss</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">232,674 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2020 before allocation of share in associate loss to long-term interest</span></div></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">553,167</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of associate loss allocated to long-term interest (please refer to Note 6)</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(23,006)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2020 after allocation of share in associate loss to long-term interest</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:5.52pt;font-weight:700;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">530,161</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    The net amount of these two items is a loss of $37.9 million which is reported on the line Gain/(loss) on investments held at fair value in the Consolidated Statements of Comprehensive Income/(Loss).</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Fair value of investments accounted for at fair value, does not take into consideration contribution from milestones that occurred after December 31, 2020, the value of the Group's consolidated Founded Entities (Vedanta, Follica, Sonde, Akili, Alivio, and Entrega), the Internal segment, or cash and cash equivalents.</span></div> 169755000 138571000 -118006000 40633000 6480000 8020000 557243000 -9295000 -78496000 714905000 -347538000 -3048000 54976000 10000000 1150000 232674000 553167000 -23006000 530161000 -37900000 62819866 0.40 0.795 0.475 6400000 12000000.0 600000 700000 1625000 500000 961538 19100000 156000000.0 49200000 2000000.0 6500000 2000000.0 3300000 1200000 8000000.0 10000000.0 579038 7100000 18700000 -23000000.0 5285102 15.14 0.709 0.443 102000000.0 72400000 5000000.0 0.443 0.316 40600000 0.284 0.314 -6300000 445600000 557200000 700000 -2100000 -200900000 555500 45000000.0 -1333333 -101600000 54800000 191200000 0.126 0.618 0.419 41700000 14400000 11500000 14300000 0.349 -11500000 10300000 33000000.0 7680700 9300000 2119696 0.058 71900000 2119696 -3000000.0 200000 100000 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes the gain on deconsolidation recognized by the Company:</span></div><div style="margin-bottom:5.25pt;text-align:justify"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Year ended December 31,</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on deconsolidation of Akili</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41,730 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on deconsolidation of Vor</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,357 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on deconsolidation of Karuna</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">102,038 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on deconsolidation of Gelesis [Note 6]</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">156,014 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total gain on deconsolidation</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">264,409 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41,730 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> 0 0 41730000 0 6357000 0 0 102038000 0 0 156014000 0 0 264409000 41730000 Investments in Associates <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis was founded by PureTech and raised funding through preferred shares financings as well as issuances of warrants and loans. As of December 31, 2018, PureTech maintained control of Gelesis and the subsidiary’s financial results were fully consolidated in the Group’s consolidated financial statements. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On July 1, 2019, the Gelesis Board of Directors was restructured, resulting in two of the three PureTech representatives resigning from the Board with PureTech retaining no ability to reappoint directors to these board seats. As a result of this restructuring, PureTech lost control over Gelesis’ Board of Directors, which triggered a loss of control over the entity. At the deconsolidation date, PureTech held a 25.2 percent voting interest in Gelesis. As of July 1, 2019, Gelesis was deconsolidated from the Group’s financial statements, resulting in only the profits and losses generated by Gelesis through the deconsolidation date being included in the Group’s Consolidated Statement of Income/(Loss) and Other Comprehensive Income/(Loss). At the date of deconsolidation, PureTech recorded a $156.0 million gain on the deconsolidation of Gelesis, which was recorded to the Gain on the deconsolidation of subsidiary line item in the Consolidated Statement of Income/(Loss) and Other Comprehensive Income/(Loss). While the Company no longer controls Gelesis, it was concluded that PureTech still has significant influence over Gelesis by virtue of its large, albeit minority, ownership stake and its continued representation on Gelesis’ Board of Directors. PureTech still has the power to participate in the financial and operating policy decisions of the entity, although it does not control these policies. As PureTech has significant influence over Gelesis, the entity is accounted for as an associate under IAS 28, starting at the date of deconsolidation.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Upon the date of deconsolidation, PureTech held preferred shares and common shares of Gelesis and a warrant issued by Gelesis to PureTech. PureTech’s investment in common shares of Gelesis is subject to equity method accounting with an initial investment of $16.4 million. In accordance with IAS 28, PureTech’s investment was adjusted by the share of profits and losses generated by Gelesis subsequent to the date of deconsolidation. See table below for the Group's share in the profits and losses of Gelesis for the periods presented.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The preferred shares and warrant held by PureTech fall under the guidance of IFRS 9 and are treated as financial assets held at fair value, where changes to the fair value of the preferred shares and warrant are recorded through the Consolidated Statement of Income/(Loss) and Other Comprehensive Income/(Loss), in accordance with IFRS 9. The fair value of the preferred shares and warrant at deconsolidation was $49.2 million. See Note 5 for changes in the fair value subsequent to deconsolidation date.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment loss for the year ended December 31, 2019</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Following the issuance of the Gelesis Series 3 Preferred Shares at a higher valuation than the previous round with some favorable liquidation provisions primarily to PureTech and also to the other Series 3 preferred share investors, which resulted in adjustments to the fair values of other preferred shares, warrant classes and Gelesis common stock, the Company assessed the investment in common shares held in Gelesis for impairment. Management compared the recoverable amount of the investment to its carrying amount as of December 31, 2019, which resulted in an impairment loss to the Investment in Gelesis. The recoverable amount was estimated based on the fair value of the Gelesis common shares held by PureTech, which are considered to be within Level 3 of the fair value hierarchy. The costs of disposal are immaterial for the calculation of Gelesis investment’s recoverable amount. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the year ended December 31, 2019, the total fair value of common shares was determined utilizing a hybrid valuation approach with significant unobservable inputs within the PureTech valuation framework (refer to Note 16). The multi-scenario hybrid valuation approach utilized the recent transaction method within an option pricing framework and an IPO scenario within a probability-weighted-expected return framework to determine the value allocation for the common share class of Gelesis. The fair value of the common shares was determined as the calculated business enterprise value allocated to the outstanding common shares treated as call options within the OPM or the value of common shares within the PWERM. The PWERM maintained a 75.0 percent probability of occurrence while the OPM maintained a 25.0 percent probability of occurrence. The probability weighted term to exit was 1.57 years. The discount rate utilized was 20.0 percent while the risk-free rate and volatility utilized were 1.62 percent and 56.0 percent, respectively.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The impairment loss amounted to $42.9 million and was recorded to Impairment of investment in associate within the Consolidated Statement of Comprehensive Income/(Loss) for the year ended December 31, 2019. As of December 31, 2019 the investment in Gelesis was $10.6 million, which is equal to the fair value of the common shares held by PureTech.</span></div><div style="margin-bottom:5.25pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the year ended December 31, 2020 the Group recorded its share in the losses of Gelesis and its investment in associates accounted for under the equity method was reduced to zero. Since the Group has investments in Gelesis preferred shares that are deemed to be Long-term interests, the Company continued recognizing its share in Gelesis losses while applying such losses to its preferred share investment in Gelesis accounted for as an investment held at fair value. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Karuna</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For the period of June 28, 2019 through December 2, 2019, PureTech’s investment in Karuna was subject to equity method accounting. In accordance with IAS 28, the Company’s investment was adjusted by the share of losses generated by Karuna (weighted average of 31.4 percent based on common stock ownership interest), which resulted in a net loss of $6.3 million during the year ended December 31, 2019 recorded in the line item Share of net income/(loss) of associates. Starting December 2, 2019, due to the loss of significant influence in Karuna on such date, the Company is accounting for the investment in Karuna as an investment held at fair value. See Note 5 for further detail on the Group's investment in Karuna.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">resTORbio</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For the period of January 1, 2018 through November 5, 2018, PureTech’s investment in resTORbio was subject to equity method accounting. In accordance with IAS 28, PureTech’s investment was adjusted by the share of profits and losses generated by resTORbio (34.9 percent based on common stock ownership interest) during that period, which resulted in a net loss from associates of $11.5 million that was recorded to the Consolidated Statement of Comprehensive Income/(Loss) in the line item Share of net income/(loss) of associates during the year ended December 31, 2018. See Note 5 for further detail on the Group's investment in resTORbio.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes the activity related to the investment in associates balance for the years ended December 31, 2020, 2019 and 2018.</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:87.080%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.720%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Investment in Associates</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000's</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of January 1, 2018</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investment upon initial public offering of resTORbio</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">115,210 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash investment in Associate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,500 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of net loss of resTORbio accounted for using the equity method</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(11,490)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on loss of significant influence of resTORbio</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,287 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassification of resTORbio investment upon loss of significant influence</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(117,507)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">As of December 31, 2018 and January 1, 2019</span></div></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassification of Karuna investment at initial public offering</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">118,006 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investment in Gelesis upon deconsolidation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">16,444 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of net loss of Karuna accounted for using the equity method</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,345)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of net profit of Gelesis accounted for using the equity method</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">37,136 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment of investment in Gelesis</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(42,938)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassification of investment in Karuna upon loss of significant influence</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(111,661)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">As of December 31, 2019 and January 1, 2020</span></div></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,642 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of net loss in Gelesis</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(34,117)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of other comprehensive income in Gelesis</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">469 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of losses recorded against long term interests</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">23,006 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">As of December 31, 2020</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Summarized financial information</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes the financial information of Gelesis as included in its own financial statements, adjusted for fair value adjustments at deconsolidation and differences in accounting policies. The table also reconciles the summarized financial information to the carrying amount of the Company’s interest in Gelesis. The information for the year ended December 31, 2019 includes the results of Gelesis only for the period July 1, 2019 to December 31, 2019, as Gelesis was consolidated prior to this period.</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:8pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of and for the year ended December 31,</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Percentage ownership interest</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47.9</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">49.3 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-current assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">372,184</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">369,336 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Current assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">92,875</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">40,079 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-current liabilities</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(133,743)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(82,406)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Current liabilities</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(300,748)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(216,852)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non controlling interests and options issued to third parties</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(6,577)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,542)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net assets attributable to shareholders of Gelesis Inc.</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">23,989</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">108,615 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Group's share of net assets</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,481</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">53,580 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Goodwill</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,216</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(42,702)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(42,938)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Recorded against Long-term Interests</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">23,006</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Investment in associate</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,642 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Revenue</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">21,442</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) from continuing operations (100%)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(71,157)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">74,573 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total comprehensive income/(loss) (100%)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(70,178)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">74,573 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Group's share in income/(loss) from continuing operations</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(34,117)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">37,136 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Group's share of total comprehensive income/(loss)</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(33,648)</span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">37,136 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> 0.252 156000000.0 16400000 49200000 0.750 0.250 1.57 0.200 0.0162 0.560 -42900000 10600000 0.314 -6300000 0.349 -11500000 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes the activity related to the investment in associates balance for the years ended December 31, 2020, 2019 and 2018.</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:87.080%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.720%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Investment in Associates</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000's</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of January 1, 2018</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investment upon initial public offering of resTORbio</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">115,210 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash investment in Associate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,500 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of net loss of resTORbio accounted for using the equity method</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(11,490)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on loss of significant influence of resTORbio</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,287 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassification of resTORbio investment upon loss of significant influence</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(117,507)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">As of December 31, 2018 and January 1, 2019</span></div></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassification of Karuna investment at initial public offering</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">118,006 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investment in Gelesis upon deconsolidation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">16,444 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of net loss of Karuna accounted for using the equity method</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,345)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of net profit of Gelesis accounted for using the equity method</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">37,136 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment of investment in Gelesis</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(42,938)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassification of investment in Karuna upon loss of significant influence</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(111,661)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">As of December 31, 2019 and January 1, 2020</span></div></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,642 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of net loss in Gelesis</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(34,117)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of other comprehensive income in Gelesis</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">469 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of losses recorded against long term interests</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">23,006 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">As of December 31, 2020</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> 0 115210000 3500000 -11490000 10287000 -117507000 0 118006000 16444000 -6345000 37136000 -42938000 -111661000 10642000 -34117000 469000 -23006000 0 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes the financial information of Gelesis as included in its own financial statements, adjusted for fair value adjustments at deconsolidation and differences in accounting policies. The table also reconciles the summarized financial information to the carrying amount of the Company’s interest in Gelesis. The information for the year ended December 31, 2019 includes the results of Gelesis only for the period July 1, 2019 to December 31, 2019, as Gelesis was consolidated prior to this period.</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:8pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of and for the year ended December 31,</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Percentage ownership interest</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47.9</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">49.3 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-current assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">372,184</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">369,336 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Current assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">92,875</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">40,079 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-current liabilities</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(133,743)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(82,406)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Current liabilities</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(300,748)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(216,852)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non controlling interests and options issued to third parties</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(6,577)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,542)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net assets attributable to shareholders of Gelesis Inc.</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">23,989</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">108,615 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Group's share of net assets</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,481</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">53,580 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Goodwill</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,216</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(42,702)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(42,938)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Recorded against Long-term Interests</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">23,006</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Investment in associate</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,642 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Revenue</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">21,442</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) from continuing operations (100%)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(71,157)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">74,573 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total comprehensive income/(loss) (100%)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(70,178)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">74,573 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Group's share in income/(loss) from continuing operations</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(34,117)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">37,136 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Group's share of total comprehensive income/(loss)</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(33,648)</span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">37,136 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> 0.479 0.493 372184000 369336000 92875000 40079000 -133743000 -82406000 -300748000 -216852000 -6577000 -1542000 23989000 108615000 11481000 53580000 8216000 0 -42702000 -42938000 -23006000 0 0 10642000 21442000 0 -71157000 74573000 -70178000 74573000 -34117000 37136000 -33648000 37136000 Operating Expenses <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total operating expenses were as follows:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ending December 31,</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">General and administrative</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">49,440</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">59,358 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">47,365 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">81,859</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">85,848 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">77,402 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total operating expenses</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">131,299</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">145,206 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">124,767 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The average number of persons employed by the Group during the year, analyzed by category, was as follows:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ending December 31,</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">General and administrative</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">43</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">39 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">55 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">95</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">90 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">90 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">138</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">129 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">145 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The aggregate payroll costs of these persons were as follows:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ending December 31,</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">General and administrative</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">22,943</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">24,468 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22,939 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">20,674</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">20,682 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">20,109 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">43,616</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">45,150 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">43,048 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Detailed operating expenses were as follows:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ending December 31,</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Salaries and wages</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">29,403</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">27,703 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">27,274 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Healthcare benefits</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,866</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,511 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,465 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Payroll taxes</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,629</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,468 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,672 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">10,718</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,468 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">12,637 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total payroll costs</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">43,616</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">45,150 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">43,048 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other selling, general and administrative expenses</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">26,497</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">34,890 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">24,426 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other research and development expenses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">61,186</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">65,166 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">57,293 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total other operating expenses</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">87,683</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100,056 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">81,719 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total operating expenses</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">131,299</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">145,206 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">124,767 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Auditors remuneration:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ending December 31,</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Audit of these financial statements</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,145</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">870 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">652 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Audit of the financial statements of subsidiaries</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">291</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">290 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">200 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Audit-related assurance services</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">490</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">163 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">162 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-audit related services</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">173</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">778 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">159 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,099</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,101 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,173 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Please refer to Note 8 for further disclosures related to share-based payments and Note 24 for management’s remuneration disclosures.</span></div> <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total operating expenses were as follows:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ending December 31,</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">General and administrative</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">49,440</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">59,358 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">47,365 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">81,859</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">85,848 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">77,402 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total operating expenses</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">131,299</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">145,206 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">124,767 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> 49440000 59358000 47365000 81859000 85848000 77402000 131299000 145206000 124767000 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The average number of persons employed by the Group during the year, analyzed by category, was as follows:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ending December 31,</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">General and administrative</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">43</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">39 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">55 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">95</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">90 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">90 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">138</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">129 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">145 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> 43 39 55 95 90 90 138 129 145 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The aggregate payroll costs of these persons were as follows:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ending December 31,</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">General and administrative</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">22,943</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">24,468 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22,939 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">20,674</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">20,682 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">20,109 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">43,616</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">45,150 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">43,048 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> 22943000 24468000 22939000 20674000 20682000 20109000 43616000 45150000 43048000 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Detailed operating expenses were as follows:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ending December 31,</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Salaries and wages</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">29,403</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">27,703 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">27,274 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Healthcare benefits</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,866</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,511 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,465 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Payroll taxes</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,629</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,468 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,672 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">10,718</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,468 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">12,637 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total payroll costs</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">43,616</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">45,150 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">43,048 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other selling, general and administrative expenses</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">26,497</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">34,890 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">24,426 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other research and development expenses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">61,186</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">65,166 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">57,293 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total other operating expenses</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">87,683</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100,056 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">81,719 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total operating expenses</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">131,299</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">145,206 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">124,767 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> 29403000 27703000 27274000 1866000 1511000 1465000 1629000 1468000 1672000 10718000 14468000 12637000 43616000 45150000 43048000 26497000 34890000 24426000 61186000 65166000 57293000 87683000 100056000 81719000 131299000 145206000 124767000 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Auditors remuneration:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ending December 31,</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Audit of these financial statements</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,145</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">870 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">652 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Audit of the financial statements of subsidiaries</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">291</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">290 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">200 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Audit-related assurance services</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">490</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">163 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">162 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-audit related services</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">173</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">778 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">159 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,099</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,101 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,173 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Please refer to Note 8 for further disclosures related to share-based payments and Note 24 for management’s remuneration disclosures.</span></div> 1145000 870000 652000 291000 290000 200000 490000 163000 162000 173000 778000 159000 2099000 2101000 1173000 Share-based Payments <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payments includes stock options, restricted stock units (“RSUs”) and performance-based RSUs in which the expense is recognized based on the grant date fair value of these awards.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based Payment Expense</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group share-based payment expense for the years ended December 31, 2020, 2019 and 2018, were comprised of charges related to the PureTech Health plc incentive stock and stock option issuances and subsidiary stock plans.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table provides the classification of the Group’s consolidated share-based payment expense as reflected in the Consolidated Statement of Income/(Loss):</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ending December 31,</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">General and administrative</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">7,650</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,677 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,293 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,068</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,791 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,344 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">10,718</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,468 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">12,637 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Ariya Stock Option Exchange</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In conjunction with the acquisition of the remaining minority interests of PureTech LYT (previously named Ariya Therapeutics, Inc.) (Please refer to Note 18), PureTech Health exchanged subsidiary stock options previously granted to the co-inventors and advisors of PureTech LYT with stock options to purchase 2,147,965 of the Company's ordinary shares under the PureTech Health Performance Share Plan. As this was an exchange of awards within the consolidated group, whereby the Company's stock options were replacing Ariya's stock options, the exchange is accounted for as a modification of the original award and the incremental fair value on the date of the replacement is amortized over the remaining vesting period of the awards.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Performance Share Plan</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In June 2015, the Group adopted the Performance Stock Plan (“PSP”). Under the PSP and subsequent amendments, awards of ordinary shares may be made to the Directors, senior managers and employees of, and other individuals providing services to the Company and its subsidiaries up to a maximum authorized amount of 10.0 percent of the total ordinary shares outstanding. The shares have various vesting terms over a period of service between two and four years, provided the recipient remains continuously engaged as a service provider.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The share-based awards granted under the PSP are equity settled and expire 10 years from the grant date. As of the years ended December 31, 2020, 2019 and 2018, the Company had issued share-based awards to purchase an aggregate of 5,835,993, 5,409,751 and 5,657,602 shares, respectively, under this plan.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">RSUs</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">RSU activity for the years ended December 31, 2020, 2019 and 2018 is detailed as follows:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Number of Shares/Units</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd Avg Grant Date Fair Value (GBP)</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding (Non-vested) at January 1, 2018</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,589,416</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.09</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">RSUs Granted in Period</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,860,778 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.54 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vested</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(513,324)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.06 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,338,087)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.06 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding (Non-vested) at December 31, 2018 and January 1, 2019</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6,598,783</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.29</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">RSUs Granted in Period</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,775,569 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.95 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vested</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,738,005)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.10 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding (Non-vested) at December 31, 2019 and January 1, 2020</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,636,347</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.08</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">RSUs Granted in Period</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,759,011 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.80 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vested</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,781,687)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.54 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(191,089)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.37 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding (Non-vested) at December 31, 2020 </span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,422,582</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.46</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Each RSU entitles the holder to one ordinary share on vesting and the RSU awards are based on a cliff vesting schedule over a three-year requisite service period in which the Company recognizes compensation expense on a graded basis for the RSUs. Following vesting, each recipient will be required to make a payment of one pence per ordinary share on settlement of the RSUs. Vesting of the RSUs is subject to the satisfaction of performance and market conditions. The grant date fair value of the market condition awards is measured to reflect such conditions and there is no true-up for differences between expected and actual outcomes. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company recognizes the estimated fair value of these performance-based awards as share-based compensation expense over the performance period based upon its determination of whether it is probable that the performance targets will be achieved. The Company assesses the probability of achieving the performance targets at each reporting period. Cumulative adjustments, if any, are recorded to reflect subsequent changes in the estimated outcome of performance-related conditions.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The fair value of the market and performance-based awards is based on the Monte Carlo simulation analysis utilizing a Geometric Brownian Motion process with 100,000 simulations to value those shares. The model considers share price volatility, risk-free rate and other covariance of comparable public companies and other market data to predict distribution of relative share performance.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The performance and market conditions attached to the 2020 RSU awards are based on the achievement of total shareholder return (“TSR”), with 50.0 percent of the shares under award vesting based on the achievement of absolute TSR targets, 12.5 percent of the shares under the award vesting based on TSR as compared to the FTSE 250 Index, 12.5 percent of the shares under the award vesting based on TSR as compared to the MSCI Europe Health Care Index, and 25.0 percent of the shares under the award vesting based on the achievement of strategic targets. The RSU award performance criteria have changed over time as the criteria is continually evaluated by the Group’s Remuneration Committee.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:115%">In 2017, the Company granted certain executives RSUs that vested based on service, market and performance conditions, as described above. The vesting of all RSUs was achieved by December 31, 2019 where all service, market and performance conditions were met. The remuneration committee of PureTech's board of directors approved the achievement of the vesting conditions as of December 31, 2019 and reached the decision to cash settle the 2017 RSUs. The settlement value was determined based on the 3 day average closing price of the shares. The settlement value was $12.5 million. The settlement value did not exceed the fair value at settlement date and as such the cash settlement was treated as an equity transaction, whereby the full repurchase cash settlement amount was charged to equity in Other reserves.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:115%">In 2018, the Company granted certain executives RSUs that vested based on service, market and performance conditions, as described above. The remuneration committee of PureTech's board of directors approved the achievement of certain vesting conditions as of July 2020 and reached the decision to cash settle a portion of the 2018 RSUs to certain executives. The settlement value was determined based on the 3 day average closing price of the shares. The settlement value was $0.4 million. The settlement value did not exceed the fair value at settlement date and as such the cash settlement was treated as an equity transaction, whereby the full repurchase cash settlement amount was charged to equity in Other reserves.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company incurred share-based payment expenses for performance and market based RSUs of $5.7 million, $2.2 million and $2.3 million for the years ended December 31, 2020, 2019 and 2018, respectively.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Stock Options</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Stock option activity for the years ended December 31, 2020, 2019 and 2018 is detailed as follows:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:51.621%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.722%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Number of Options</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd Average Exercise Price (GBP)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd Average of<br/>remaining contractual<br/>term (in years)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd Average Stock Price at Exercise (GBP)</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding at January 1, 2018</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,343,085</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.22</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #183964;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Granted</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,796,820 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.57 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exercised</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(64,171)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.20 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.56</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.19pt;font-weight:700;line-height:120%">Options Exercisable at December 31, 2018 and January 1, 2019</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,195,929</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.26</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">7.92</span></td><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding at at December 31, 2018 and January 1, 2019</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,075,734</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.40</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8.78</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Granted</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,634,183 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.84 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #183964;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exercised</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(237,090)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.98 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.81</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.19pt;font-weight:700;line-height:120%">Options Exercisable at December 31, 2019 and January 1, 2020</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,349,921</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.93</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8.34</span></td><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding at at December 31, 2019 and January 1, 2020</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,472,827</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.16</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8.55</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Granted</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,076,982 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.14 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #183964;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exercised</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(514,410)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.52 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.88</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,119,313)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.88 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Options Exercisable at December 31, 2020</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,447,405</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.98</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">7.46</span></td><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding at December 31, 2020</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">10,916,086</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.81</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8.38</span></td><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:0 1pt"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The fair value of the stock options awarded by the Company was estimated at the grant date using the Black-Scholes option valuation model, considering the terms and conditions upon which options were granted, with the following weighted-average assumptions:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">At December 31,</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected volatility</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">41.25</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">35.68 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">44.18 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected terms (in years)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6.11</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5.81</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6.08</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Risk-free interest rate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.53</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.85 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.79 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected dividend yield</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant date fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">$1.72</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$2.23 </span></td><td style="padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$0.96 </span></td><td style="padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share price at grant date</span></td><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">$4.30</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$2.57 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$2.05 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company incurred share-based payment expense for the stock options of $2.1 million, $9.2 million and $1.4 million for the years ended December 31, 2020, 2019 and 2018, respectively. The significant decrease for the year ended December 31, 2020, as compared to the year ended December 31, 2019, is largely attributable to the exchange of the Ariya awards with the Company's </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">stock options in the year ended December 31, 2019, which resulted in an additional expense recorded in such year, as described above.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For shares outstanding as of December 31, 2020, the range of exercise prices is detailed as follow:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Range of Exercise Prices (GBP)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Options<br/>Outstanding</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd<br/>Average<br/>Exercise<br/>Price (GBP)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd Average of<br/>remaining contractual<br/>term (in years)</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.01</span></div></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,122,965 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8.76</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.00 to 2.00</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,703,639 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.47 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6.99</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.00 to 3.00</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,539,482 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.51 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9.45</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.00 to 4.00</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,550,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.51 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9.97</span></td></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">10,916,086</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.81</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8.38</span></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For shares exercisable at December 31, 2020, utilizing the closing share price on December 31, 2020, the estimated tax obligation associated with the share-based payments transferable to the tax authority on the employee's behalf was $6.9 million. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech LLC Incentive Stock Issuance</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In May 2015 and August 2014, the directors of PureTech Health LLC approved the issuance of shares to the management team, directors and advisors of PureTech Health LLC, subject to vesting restrictions. The share-based awards granted under the 2016 PureTech LLC Incentive Stock Issuance Plan are equity settled and expire 10 years from the grant date. No additional shares will be granted under this compensation arrangement. The fair value of the shares awarded was estimated as of the date of grant.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company incurred an expense of $0.2 million in share-based payment expense for the year ended December 31, 2018, related to PureTech Health LLC incentive compensation. No share-based payment expense was incurred related to PureTech Health LLC incentive compensation for the years ended December 31, 2020, and 2019, respectively.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of December 31, 2020, all shares related to the pre-IPO incentive compensation plan had fully vested.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary Plans</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Certain subsidiaries of the Group have adopted stock option plans. A summary of stock option activity by number of shares in these subsidiaries is presented in the following table:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.265%"><tr><td style="width:1.0%"/><td style="width:27.650%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Outstanding as of January 1, 2020</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Granted During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Exercised During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Expired During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Forfeited During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Outstanding as of December 31, 2020</span></div></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Alivio</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,698,244</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">189,924</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,888,168</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">972,000</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(10,000)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">962,000</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,309,040</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,309,040</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,829,004</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">363,830</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,192,834</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta</span></td><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,450,100</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">493,951</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(813)</span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(201,350)</span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,741,888</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.265%"><tr><td style="width:1.0%"/><td style="width:27.650%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Outstanding as of January 1, 2019</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Granted During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Exercised During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Expired During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Forfeited During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Outstanding as of December 31, 2019</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,681,732 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(110,386)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,571,346)¹</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Alivio</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,393,750 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,329,494 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,125)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(21,875)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,698,244 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech LYT</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,180,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,180,000)²</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Commense</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">540,416 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(540,416)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">914,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">58,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">972,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,229,452 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">79,588 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,309,040 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Karuna</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,949,927 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,949,927)¹</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22,500 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,806,504 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,829,004 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta</span></td><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,373,750 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">154,193 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(77,843)</span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,450,100 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    These shares represent the options outstanding on the date of deconsolidation of Karuna and Gelesis.</span></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    These shares represent the options outstanding on the date of exchange to PureTech stock options.</span></div><div style="margin-bottom:2pt"><span><br/></span></div><div style="margin-bottom:2pt"><span><br/></span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.265%"><tr><td style="width:1.0%"/><td style="width:27.650%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Outstanding as of January 1, 2018</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Granted During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Exercised During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Expired During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Forfeited During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Outstanding as of December 31, 2018</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,728,232 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">953,500 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,681,732 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Alivio</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,393,750 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,393,750 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Akili</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,385,355 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,385,355)¹</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech LYT</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,180,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,180,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Commense</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">418,750 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">121,666 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">540,416 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">867,750 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">60,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,750)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10,000)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">914,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,271,302 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(41,850)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,229,452 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.265%"><tr><td style="width:1.0%"/><td style="width:27.650%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Karuna</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">855,427 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,111,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,125)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(12,375)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,949,927 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Knode</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">32,500 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(32,500)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">35,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,250)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,250)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22,500 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tal</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,663,806 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(30,250)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,750)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,630,806 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Sync Project</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,080,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,080,000)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta</span></td><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,194,014 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">278,786 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(24,800)</span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(74,250)</span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,373,750 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    These shares represent the options outstanding on the date of Akili’s deconsolidation.</span></div><div style="margin-bottom:2pt"><span><br/></span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The weighted-average exercise prices and remaining contractual life for the options outstanding as of December 31, 2020 were as follows:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Outstanding at December 31, 2020</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Number of options</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Weighted-average exercise price</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Weighted-average contractual life outstanding</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Alivio</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,888,168</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.21</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">7.65</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">962,000</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.70</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.80</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,309,040</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.89</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6.29</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,192,834</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.19</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8.76</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta</span></td><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,741,888</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">7.48</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6.15</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The weighted average exercise prices for the options granted for the years ended December 31, 2020, 2019 and 2018 were as follows:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ended December 31,</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Alivio</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.47</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.49 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech LYT</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.03 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Commense</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.34 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.95 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.03 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Karuna</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9.42 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.18</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.20 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta</span></td><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">19.59</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19.13 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14.66 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The weighted average exercise prices for options forfeited during the year ended December 31, 2020 were as follows: </span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Forfeited during the year ended December 31, 2020</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Number of options</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Weighted-average exercise price</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">201,350</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">16.03</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The weighted average exercise prices for options exercisable as of December 31, 2020 were as follows:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.566%"><tr><td style="width:1.0%"/><td style="width:46.096%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.501%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.501%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.502%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Exercisable at December 31,</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Number of Options</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Weighted-average exercise price</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Exercise Price Range<br/>$</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Alivio</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,888,168</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.04</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.03-0.49</span></div></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">918,164</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.64</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.03-2.36</span></div></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,273,326</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.89</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.03-1.40</span></div></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">774,238</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.20</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.13-0.20</span></div></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta</span></td><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,119,289</span></td><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11.64</span></td><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.02-19.94</span></div></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Significant Subsidiary Plans</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Vedanta 2010 Stock Incentive Plan</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In 2010, the Board of Directors for Vedanta approved the 2010 Stock Incentive Plan (the “Vedanta Plan”). Through subsequent amendments, as of December 31, 2020, it allowed for the issuance of 2,145,867 share-based compensation awards through incentive share options, nonqualified share options, and restricted shares to employees, directors, and nonemployees providing services to Vedanta. At December 31, 2020, 178,929 shares remained available for issuance under the Vedanta Plan.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The options granted under Vedanta Plan are equity settled and expire 10 years from the grant date. Typically, the awards vest in four years but vesting conditions can vary based on the discretion of Vedanta’s Board of Directors.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Options granted under the Vedanta Plan are exercisable at a price per share not less than the fair market value of the underlying ordinary shares on the date of grant. The estimated fair value of options, including the effect of estimated forfeitures, is recognized over the options’ vesting period.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The fair value of the stock option grants has been estimated at the date of grant using the Black-Scholes option pricing model with the following range of assumptions:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.566%"><tr><td style="width:1.0%"/><td style="width:46.096%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.501%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.501%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.502%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Assumption/Input</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected award life (in years)</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6.00-10.00</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5.86-6.07</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6.03-6.16</span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected award price volatility</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">89.24%-95.46%</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">89.24%-95.46%</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">91.60%-92.56%</span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Risk free interest rate</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.32%-0.87%</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.73%-1.88%</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.65%-2.78%</span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected dividend yield</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">—</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant date fair value</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">$13.09-$16.54</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$14.12-$15.61</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$11.21-$11.26</span></div></td></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share price at grant date</span></td><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%"> $19.59</span></div></td><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$18.71-$19.94</span></div></td><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$14.66</span></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta incurred share-based compensation expense of $2.4 million, $1.7 million and $2.1 million for the years ended December 31, 2020, 2019 and 2018, respectively.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Gelesis 2016 Stock Incentive Plan</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In September 2016, the Directors of Gelesis approved the 2016 Stock Incentive Plan (the “2016 Gelesis Plan”) which provides for the grant of incentive stock options, nonqualified stock options, and restricted stock to employees, directors, and nonemployees providing services to Gelesis. At 30 June 2019, 329,559 shares remained available for issuance under the Gelesis Plan.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The options granted under the 2016 Gelesis Plan are equity settled and expire 10 years from the grant date. Typically, the awards vest in four years but vesting conditions can vary based on the discretion of Gelesis Board of Directors.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Options granted under the 2016 Gelesis Plan are exercisable at a price per share not less than the fair market value of the underlying ordinary shares on the date of grant. The estimated fair value of options, including the effect of estimated forfeitures, is recognized over the options’ vesting period.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The fair value of the stock option grants has been estimated at the date of grant using the Black-Scholes option pricing model with the following weighted average assumptions:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Assumption/Input</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected award life (in years)</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6.22</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected award price volatility</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">64.58 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Risk free interest rate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.79 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected dividend yield</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">—</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant date fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">$—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$— </span></td><td style="padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$7.84 </span></td><td style="padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share price at grant date</span></td><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">$—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$— </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$12.82 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis used an average historical share price volatility based on an analysis of reported data for a peer group of comparable companies which were selected based upon industry similarities. As there is not sufficient historical share exercise data to calculate the expected term of the options, Gelesis elected to use the “simplified” method for all options granted at the money to value share option grants. Under this approach, the weighted average expected life is presumed to be the average of the vesting term and the contractual term of the option.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis incurred share-based compensation expense of $2.4 million for the six month period prior to deconsolidation ended June 30, 2019 and $3.9 million for the year ended December 31, 2018.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Karuna Pharmaceuticals, Inc. 2009 Stock Incentive Plan</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In 2009, the Board of Directors for Karuna Pharmaceuticals, Inc. approved the 2009 Stock Incentive Plan (the “Karuna 2009 Plan”). It allowed for the issuance of 1,000,000 share-based compensation awards through stock options, restricted stock units and other stock-based awards under the Karuna 2009 Plan to employees, officers, directors, consultants and advisors of Karuna. At 15 March 2019, 106,865 shares remained available for issuance under the Karuna 2009 Plan.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The options granted under the Karuna 2009 Plan are equity settled and expire 10 years from the grant date. Typically, the awards vest in four years but vesting conditions can vary based on the discretion of Karuna’s Board of Directors.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Options granted under the Karuna 2009 Plan are exercisable at a price per share not less than the fair market value of the underlying ordinary shares on the date of grant. The estimated fair value of options, including the effect of estimated forfeitures, is recognized over the options’ vesting period.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The fair value of the stock option grants has been estimated at the date of grant using the Black-Scholes option pricing model with the following weighted average assumptions:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Assumption/Input</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected award life (in years)</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6.07</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected award price volatility</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">50.28 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Risk free interest rate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.95 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected dividend yield</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant date fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">$—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$— </span></td><td style="padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$3.51 </span></td><td style="padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share price at grant date</span></td><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">$—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$— </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$7.08 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Karuna incurred share-based compensation expense of $1.2 million for the period prior to deconsolidation ended March 15, 2019 and $1.9 million for the years ended December 31, 2018.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other Plans</span></div>The stock compensation expense under plans at other subsidiaries of the Group not including Gelesis, Vedanta and Karuna was $0.42 million, $0.01 million and $0.8 million for the years ended December 31, 2020, 2019 and 2018, respectively. The negative expense incurred during the year ended December 31, 2019 was largely attributable to Commense forfeitures. <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table provides the classification of the Group’s consolidated share-based payment expense as reflected in the Consolidated Statement of Income/(Loss):</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ending December 31,</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">General and administrative</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">7,650</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,677 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,293 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,068</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,791 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,344 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">10,718</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,468 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">12,637 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> -7650000 -10677000 -5293000 -3068000 -3791000 -7344000 10718000 14468000 12637000 2147965 0.100 5835993 5409751 5657602 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">RSU activity for the years ended December 31, 2020, 2019 and 2018 is detailed as follows:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Number of Shares/Units</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd Avg Grant Date Fair Value (GBP)</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding (Non-vested) at January 1, 2018</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,589,416</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.09</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">RSUs Granted in Period</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,860,778 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.54 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vested</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(513,324)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.06 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,338,087)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.06 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding (Non-vested) at December 31, 2018 and January 1, 2019</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6,598,783</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.29</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">RSUs Granted in Period</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,775,569 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.95 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vested</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,738,005)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.10 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding (Non-vested) at December 31, 2019 and January 1, 2020</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,636,347</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.08</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">RSUs Granted in Period</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,759,011 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.80 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vested</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,781,687)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.54 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(191,089)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.37 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding (Non-vested) at December 31, 2020 </span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,422,582</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.46</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> 5589416 1.09 2860778 1.54 513324 1.06 1338087 1.06 6598783 1.29 1775569 2.95 3738005 1.10 0 0 4636347 2.08 1759011 1.80 2781687 1.54 191089 2.37 3422582 2.46 12500000 400000 5700000 2200000 2300000 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Stock option activity for the years ended December 31, 2020, 2019 and 2018 is detailed as follows:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:51.621%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.722%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Number of Options</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd Average Exercise Price (GBP)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd Average of<br/>remaining contractual<br/>term (in years)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd Average Stock Price at Exercise (GBP)</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding at January 1, 2018</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,343,085</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.22</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #183964;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Granted</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,796,820 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.57 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exercised</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(64,171)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.20 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.56</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.19pt;font-weight:700;line-height:120%">Options Exercisable at December 31, 2018 and January 1, 2019</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,195,929</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.26</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">7.92</span></td><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding at at December 31, 2018 and January 1, 2019</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,075,734</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.40</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8.78</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Granted</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,634,183 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.84 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #183964;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exercised</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(237,090)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.98 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.81</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.19pt;font-weight:700;line-height:120%">Options Exercisable at December 31, 2019 and January 1, 2020</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,349,921</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.93</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8.34</span></td><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding at at December 31, 2019 and January 1, 2020</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,472,827</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.16</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8.55</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Granted</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,076,982 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.14 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #183964;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exercised</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(514,410)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.52 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.88</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,119,313)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.88 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Options Exercisable at December 31, 2020</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,447,405</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.98</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">7.46</span></td><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding at December 31, 2020</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">10,916,086</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.81</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8.38</span></td><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:0 1pt"/></tr></table></div> 2343085 1.22 2796820 1.57 64171 1.20 1.56 0 0 1195929 1.26 P7Y11M1D 5075734 1.40 P8Y9M10D 3634183 0.84 237090 1.98 2.81 0 0 4349921 0.93 P8Y4M2D 8472827 1.16 P8Y6M18D 4076982 3.14 514410 1.52 2.88 1119313 1.88 5447405 0.98 P7Y5M15D 10916086 1.81 P8Y4M17D <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The fair value of the stock options awarded by the Company was estimated at the grant date using the Black-Scholes option valuation model, considering the terms and conditions upon which options were granted, with the following weighted-average assumptions:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">At December 31,</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected volatility</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">41.25</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">35.68 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">44.18 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected terms (in years)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6.11</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5.81</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6.08</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Risk-free interest rate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.53</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.85 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.79 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected dividend yield</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant date fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">$1.72</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$2.23 </span></td><td style="padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$0.96 </span></td><td style="padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share price at grant date</span></td><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">$4.30</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$2.57 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$2.05 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/></tr></table></div> 0.4125 0.3568 0.4418 6.11 5.81 6.08 0.0053 0.0185 0.0279 0 0 0 1.72 2.23 0.96 4.30 2.57 2.05 2100000 9200000 1400000 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For shares outstanding as of December 31, 2020, the range of exercise prices is detailed as follow:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Range of Exercise Prices (GBP)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Options<br/>Outstanding</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd<br/>Average<br/>Exercise<br/>Price (GBP)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd Average of<br/>remaining contractual<br/>term (in years)</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.01</span></div></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,122,965 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8.76</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.00 to 2.00</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,703,639 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.47 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6.99</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.00 to 3.00</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,539,482 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.51 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9.45</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.00 to 4.00</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,550,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.51 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9.97</span></td></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">10,916,086</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.81</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8.38</span></td></tr></table></div> 0.01 2122965 0 P8Y9M3D 1.00 2.00 4703639 1.47 P6Y11M26D 2.00 3.00 1539482 2.51 P9Y5M12D 3.00 4.00 2550000 3.51 P9Y11M19D 10916086 1.81 P8Y4M17D 6900000 200000 <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary Plans</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Certain subsidiaries of the Group have adopted stock option plans. A summary of stock option activity by number of shares in these subsidiaries is presented in the following table:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.265%"><tr><td style="width:1.0%"/><td style="width:27.650%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Outstanding as of January 1, 2020</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Granted During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Exercised During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Expired During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Forfeited During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Outstanding as of December 31, 2020</span></div></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Alivio</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,698,244</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">189,924</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,888,168</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">972,000</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(10,000)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">962,000</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,309,040</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,309,040</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,829,004</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">363,830</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,192,834</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta</span></td><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,450,100</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">493,951</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(813)</span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(201,350)</span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,741,888</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.265%"><tr><td style="width:1.0%"/><td style="width:27.650%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Outstanding as of January 1, 2019</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Granted During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Exercised During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Expired During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Forfeited During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Outstanding as of December 31, 2019</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,681,732 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(110,386)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,571,346)¹</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Alivio</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,393,750 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,329,494 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,125)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(21,875)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,698,244 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech LYT</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,180,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,180,000)²</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Commense</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">540,416 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(540,416)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">914,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">58,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">972,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,229,452 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">79,588 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,309,040 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Karuna</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,949,927 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,949,927)¹</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22,500 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,806,504 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,829,004 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta</span></td><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,373,750 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">154,193 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(77,843)</span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,450,100 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    These shares represent the options outstanding on the date of deconsolidation of Karuna and Gelesis.</span></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    These shares represent the options outstanding on the date of exchange to PureTech stock options.</span></div><div style="margin-bottom:2pt"><span><br/></span></div><div style="margin-bottom:2pt"><span><br/></span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.265%"><tr><td style="width:1.0%"/><td style="width:27.650%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Outstanding as of January 1, 2018</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Granted During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Exercised During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Expired During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Forfeited During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Outstanding as of December 31, 2018</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,728,232 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">953,500 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,681,732 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Alivio</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,393,750 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,393,750 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Akili</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,385,355 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,385,355)¹</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech LYT</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,180,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,180,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Commense</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">418,750 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">121,666 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">540,416 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">867,750 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">60,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,750)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10,000)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">914,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,271,302 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(41,850)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,229,452 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.265%"><tr><td style="width:1.0%"/><td style="width:27.650%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Karuna</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">855,427 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,111,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,125)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(12,375)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,949,927 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Knode</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">32,500 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(32,500)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">35,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,250)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,250)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22,500 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tal</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,663,806 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(30,250)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,750)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,630,806 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Sync Project</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,080,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,080,000)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta</span></td><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,194,014 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">278,786 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(24,800)</span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(74,250)</span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,373,750 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    These shares represent the options outstanding on the date of Akili’s deconsolidation.</span></div> 3698244 189924 0 0 0 3888168 972000 0 0 0 -10000 962000 1309040 0 0 0 0 1309040 1829004 363830 0 0 0 2192834 1450100 493951 -813 0 -201350 1741888 3681732 0 0 -110386 -3571346 0 2393750 1329494 -3125 0 -21875 3698244 2180000 0 0 0 -2180000 0 540416 0 0 0 -540416 0 914000 58000 0 0 0 972000 1229452 79588 0 0 0 1309040 1949927 0 0 0 -1949927 0 22500 1806504 0 0 0 1829004 1373750 154193 0 0 -77843 1450100 2728232 953500 0 0 0 3681732 2393750 0 0 0 0 2393750 2385355 0 0 0 -2385355 0 0 2180000 0 0 0 2180000 418750 121666 0 0 0 540416 867750 60000 0 -3750 -10000 914000 1271302 0 0 -41850 0 1229452 855427 1111000 0 -4125 -12375 1949927 32500 0 0 -32500 0 0 35000 0 0 -6250 -6250 22500 1663806 0 0 -30250 -2750 1630806 1080000 0 0 0 -1080000 0 1194014 278786 0 -24800 -74250 1373750 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The weighted-average exercise prices and remaining contractual life for the options outstanding as of December 31, 2020 were as follows:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Outstanding at December 31, 2020</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Number of options</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Weighted-average exercise price</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Weighted-average contractual life outstanding</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Alivio</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,888,168</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.21</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">7.65</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">962,000</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.70</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.80</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,309,040</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.89</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6.29</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,192,834</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.19</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8.76</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta</span></td><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,741,888</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">7.48</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6.15</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div> 3888168 0.21 P7Y7M24D 962000 0.70 P2Y9M18D 1309040 0.89 P6Y3M14D 2192834 0.19 P8Y9M3D 1741888 7.48 P6Y1M24D <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The weighted average exercise prices for the options granted for the years ended December 31, 2020, 2019 and 2018 were as follows:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ended December 31,</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Alivio</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.47</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.49 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech LYT</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.03 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Commense</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.34 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.95 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.03 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Karuna</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9.42 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.18</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.20 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta</span></td><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">19.59</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19.13 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14.66 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> 0.47 0.49 0 0 0 0.03 0 0 1.34 0 0 1.95 0 0.03 0 0 0 9.42 0.18 0.20 0 19.59 19.13 14.66 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The weighted average exercise prices for options forfeited during the year ended December 31, 2020 were as follows: </span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Forfeited during the year ended December 31, 2020</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Number of options</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Weighted-average exercise price</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">201,350</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">16.03</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div> -201350 16.03 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The weighted average exercise prices for options exercisable as of December 31, 2020 were as follows:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.566%"><tr><td style="width:1.0%"/><td style="width:46.096%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.501%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.501%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.502%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Exercisable at December 31,</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Number of Options</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Weighted-average exercise price</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Exercise Price Range<br/>$</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Alivio</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,888,168</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.04</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.03-0.49</span></div></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">918,164</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.64</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.03-2.36</span></div></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,273,326</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.89</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.03-1.40</span></div></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">774,238</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.20</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.13-0.20</span></div></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta</span></td><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,119,289</span></td><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11.64</span></td><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.02-19.94</span></div></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div> 3888168 0.04 0.03 0.49 918164 0.64 0.03 2.36 1273326 0.89 0.03 1.40 774238 0.20 0.13 0.20 1119289 11.64 0.02 19.94 2145867 178929 The fair value of the stock option grants has been estimated at the date of grant using the Black-Scholes option pricing model with the following range of assumptions:<table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.566%"><tr><td style="width:1.0%"/><td style="width:46.096%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.501%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.501%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.502%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Assumption/Input</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected award life (in years)</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6.00-10.00</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5.86-6.07</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6.03-6.16</span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected award price volatility</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">89.24%-95.46%</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">89.24%-95.46%</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">91.60%-92.56%</span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Risk free interest rate</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.32%-0.87%</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.73%-1.88%</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.65%-2.78%</span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected dividend yield</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">—</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant date fair value</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">$13.09-$16.54</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$14.12-$15.61</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$11.21-$11.26</span></div></td></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share price at grant date</span></td><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%"> $19.59</span></div></td><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$18.71-$19.94</span></div></td><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$14.66</span></td></tr></table> 6.00 10.00 5.86 6.07 6.03 6.16 0.8924 0.9546 0.8924 0.9546 0.9160 0.9256 0.0032 0.0087 0.0173 0.0188 0.0265 0.0278 0 0 0 13.09 16.54 14.12 15.61 11.21 11.26 19.59 18.71 19.94 14.66 2400000 1700000 2100000 329559 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The fair value of the stock option grants has been estimated at the date of grant using the Black-Scholes option pricing model with the following weighted average assumptions:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Assumption/Input</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected award life (in years)</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6.22</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected award price volatility</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">64.58 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Risk free interest rate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.79 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected dividend yield</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">—</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant date fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">$—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$— </span></td><td style="padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$7.84 </span></td><td style="padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share price at grant date</span></td><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">$—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$— </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$12.82 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/></tr></table></div> 0 0 6.22 0 0 0.6458 0 0 0.0279 0 0 0 0 0 7.84 0 0 12.82 2400000 3900000 1000000 106865 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The fair value of the stock option grants has been estimated at the date of grant using the Black-Scholes option pricing model with the following weighted average assumptions:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Assumption/Input</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected award life (in years)</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6.07</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected award price volatility</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">50.28 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Risk free interest rate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.95 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected dividend yield</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant date fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">$—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$— </span></td><td style="padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$3.51 </span></td><td style="padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share price at grant date</span></td><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">$—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$— </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$7.08 </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/></tr></table></div> 0 0 6.07 0 0 0.5028 0 0 0.0195 0 0 0 0 0 3.51 0 0 7.08 1200000 1900000 420000 10000.00 800000 Finance Cost, net <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table shows the breakdown of finance income and costs:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the year ended December 31</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Finance income</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest from financial assets not at fair value through profit or loss</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,183</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,362 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,358 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total finance income</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,183</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,362 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,358 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Finance costs</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contractual interest expense on notes payable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(96)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(149)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(388)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest expense on other borrowings</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(496)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest expense on lease liability</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,354)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,495)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on forgiveness of debt</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">289 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on foreign currency exchange</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">68 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">137 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total finance income/(costs) – contractual</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,946)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,576)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">34 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) from change in fair value of warrant liability</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(117)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(11,890)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">82 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) from change in fair value of preferred shares and convertible notes</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(4,234)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(34,585)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22,549 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total finance income/(costs) – fair value accounting</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(4,351)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(46,475)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22,631 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total finance income/(costs) – subsidiary preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,458)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(106)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total finance income/(costs)</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(4,351)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(47,933)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22,525 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Finance income/(costs), net</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(6,115)</span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(46,147)</span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">25,917 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table shows the breakdown of finance income and costs:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the year ended December 31</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Finance income</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest from financial assets not at fair value through profit or loss</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,183</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,362 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,358 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total finance income</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,183</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,362 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,358 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Finance costs</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contractual interest expense on notes payable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(96)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(149)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(388)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest expense on other borrowings</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(496)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest expense on lease liability</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,354)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,495)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on forgiveness of debt</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">289 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on foreign currency exchange</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">68 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">137 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total finance income/(costs) – contractual</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,946)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,576)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">34 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) from change in fair value of warrant liability</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(117)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(11,890)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">82 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) from change in fair value of preferred shares and convertible notes</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(4,234)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(34,585)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22,549 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total finance income/(costs) – fair value accounting</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(4,351)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(46,475)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22,631 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total finance income/(costs) – subsidiary preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,458)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(106)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total finance income/(costs)</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(4,351)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(47,933)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22,525 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Finance income/(costs), net</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(6,115)</span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(46,147)</span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">25,917 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> 1183000 4362000 3358000 1183000 4362000 3358000 96000 149000 388000 496000 0 4000 2354000 2495000 0 0 0 289000 0 68000 137000 2946000 2576000 -34000 -117000 -11890000 82000 -4234000 -34585000 22549000 -4351000 -46475000 22631000 0 -1458000 -106000 -106000 -4351000 -47933000 22525000 -6115000 -46147000 25917000 Earnings/(Loss) per Share <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The basic and diluted loss per share has been calculated by dividing the income/(loss) for the period attributable to ordinary shareholders by the weighted average number of ordinary shares outstanding during the years ended December 31, 2020, 2019 and 2018, respectively.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Earnings/(Loss) Attributable to Owners of the Company:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:26.738%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Basic<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Diluted<br/>$000s</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Basic<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Diluted<br/>$000s</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Basic<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Diluted<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) for the year, attributable to the owners of the Company</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,985</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,985</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">421,144 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">421,144 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(43,654)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(43,654)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) attributable to ordinary shareholders</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,985</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,985</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:0 1pt"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">421,144 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">421,144 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:0 1pt"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(43,654)</span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(43,654)</span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Weighted-Average Number of Ordinary Shares:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:26.738%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Basic</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Diluted</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Basic</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Diluted</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Basic</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Diluted</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.1pt;font-weight:400;line-height:120%">Issued ordinary shares at January 1,</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">285,370,619</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">285,370,619</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">282,493,867 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">282,493,867 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">236,897,579 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">236,897,579 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Effect of shares issued</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">233,048</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">233,048</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">932,600 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">932,600 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">36,950,688 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">36,950,688 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Effect of dilutive shares (please refer to Note 8)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">7,252,246</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,355,866 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Weighted average number of ordinary shareholders at December 31,</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">285,603,667</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">292,855,913</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">283,426,467 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">291,782,333 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">273,848,267 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">273,848,267 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Earnings/(Loss) per Share:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:26.738%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Basic<br/>$</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Diluted<br/>$</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Basic<br/>$</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Diluted<br/>$</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Basic<br/>$</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Diluted<br/>$</span></td></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Basic and diluted earnings/(loss) per share</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.02</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.02</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.49 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.44 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(0.16)</span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(0.16)</span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Earnings/(Loss) Attributable to Owners of the Company:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:26.738%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Basic<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Diluted<br/>$000s</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Basic<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Diluted<br/>$000s</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Basic<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Diluted<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) for the year, attributable to the owners of the Company</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,985</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,985</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">421,144 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">421,144 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(43,654)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(43,654)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) attributable to ordinary shareholders</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,985</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,985</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:0 1pt"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">421,144 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">421,144 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:0 1pt"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(43,654)</span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(43,654)</span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> 5985000 5985000 421144000 421144000 -43654000 -43654000 5985000 5985000 421144000 421144000 -43654000 -43654000 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Weighted-Average Number of Ordinary Shares:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:26.738%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Basic</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Diluted</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Basic</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Diluted</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Basic</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Diluted</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.1pt;font-weight:400;line-height:120%">Issued ordinary shares at January 1,</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">285,370,619</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">285,370,619</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">282,493,867 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">282,493,867 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">236,897,579 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">236,897,579 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Effect of shares issued</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">233,048</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">233,048</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">932,600 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">932,600 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">36,950,688 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">36,950,688 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Effect of dilutive shares (please refer to Note 8)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">7,252,246</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,355,866 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Weighted average number of ordinary shareholders at December 31,</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">285,603,667</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">292,855,913</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">283,426,467 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">291,782,333 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">273,848,267 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">273,848,267 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> 285370619 285370619 282493867 282493867 236897579 236897579 233048 233048 932600 932600 36950688 36950688 0 7252246 0 8355866 0 0 285603667 292855913 283426467 291782333 273848267 273848267 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Earnings/(Loss) per Share:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:26.738%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Basic<br/>$</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Diluted<br/>$</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Basic<br/>$</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Diluted<br/>$</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Basic<br/>$</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Diluted<br/>$</span></td></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Basic and diluted earnings/(loss) per share</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.02</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.02</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.49 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.44 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(0.16)</span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(0.16)</span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> 0.02 0.02 1.49 1.44 -0.16 -0.16 Property and Equipment<div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:27.982%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Cost</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Laboratory and Manufacturing Equipment<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Furniture and<br/>Fixtures<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Computer Equipment and<br/>Software<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Leasehold Improvements<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Construction in<br/>process<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total<br/>$000s</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of January 1, 2019</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,306 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">488 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,431 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,924 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">239 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,388 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions, net of transfers</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,374 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,126 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">175 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,494 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,649 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22,818 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Disposals</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(183)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(168)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(9)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(45)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(405)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiaries</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,076)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(137)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(754)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,190)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,157)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassifications</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(25)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">48 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">36 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(76)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(11)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exchange differences</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(11)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">24 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2019</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,385 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,452 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,508 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">17,656 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">646 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28,647 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions, net of transfers</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,536 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">51 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">399 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,347 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,332 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Disposals</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(642)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(40)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(682)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassifications</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">141 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(141)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2020</span></td><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,420</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,452</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,519</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">18,054</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,852</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">33,297</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:27.982%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Accumulated depreciation and impairment loss</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Laboratory and Manufacturing Equipment<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Furniture and<br/>Fixtures<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Computer Equipment and<br/>Software<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Leasehold Improvements<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Construction in<br/>process<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of January 1, 2018</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,360)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(175)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(534)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(807)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,876)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,032)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(60)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(296)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,088)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,476)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Disposals</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">114 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">74 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">20 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">210 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiaries</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassifications</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exchange differences</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">56 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">21 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">77 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of January 1, 2019</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,222)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(233)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(756)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,854)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,065)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,328)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(144)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(312)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,448)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,232)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Disposals</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">102 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">138 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">20 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">265 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiaries</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,457 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">53 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">319 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,829 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassifications</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(20)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exchange differences</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2019</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,968)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(239)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,030)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,955)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(7,192)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,572)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(215)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(297)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,860)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,944)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Disposals</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">576 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">40 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">616 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2020</span></td><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(3,965)</span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(454)</span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,287)</span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(4,815)</span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(10,520)</span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:27.982%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Property and Equipment, net</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Laboratory and Manufacturing Equipment<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Furniture and<br/>Fixtures<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Computer Equipment and<br/>Software<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Leasehold Improvements<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Construction in<br/>process<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total<br/>$000s</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2019</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,417 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,213 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">478 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,701 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">646 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">21,455 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2020</span></td><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,456</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">998</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">232</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">13,239</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,852</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">22,777</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation of property and equipment is included in the General and administrative expenses and Research and development expenses line items in the Consolidated Statements of Comprehensive Income/(Loss). The Company recorded depreciation expense of $3.9 million, $3.2 million and $2.5 million for the years ended December 31, 2020, 2019 and 2018, respectively.</span></div> <table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:27.982%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Cost</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Laboratory and Manufacturing Equipment<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Furniture and<br/>Fixtures<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Computer Equipment and<br/>Software<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Leasehold Improvements<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Construction in<br/>process<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total<br/>$000s</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of January 1, 2019</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,306 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">488 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,431 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,924 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">239 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,388 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions, net of transfers</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,374 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,126 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">175 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,494 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,649 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22,818 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Disposals</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(183)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(168)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(9)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(45)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(405)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiaries</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,076)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(137)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(754)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,190)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,157)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassifications</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(25)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">48 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">36 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(76)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(11)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exchange differences</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(11)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">24 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2019</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,385 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,452 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,508 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">17,656 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">646 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28,647 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions, net of transfers</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,536 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">51 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">399 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,347 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,332 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Disposals</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(642)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(40)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(682)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassifications</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">141 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(141)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2020</span></td><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,420</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,452</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,519</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">18,054</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,852</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">33,297</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table> 7306000 488000 1431000 4924000 239000 14388000 3374000 1126000 175000 13494000 4649000 22818000 -183000 -168000 -9000 -45000 0 -405000 -3076000 0 -137000 -754000 -4190000 -8157000 -25000 6000 48000 36000 -76000 -11000 -11000 0 0 1000 24000 14000 7385000 1452000 1508000 17656000 646000 28647000 1536000 0 51000 399000 3347000 5332000 -642000 0 -40000 0 0 -682000 141000 0 0 0 -141000 0 8420000 1452000 1519000 18054000 3852000 33297000 <table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:27.982%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Accumulated depreciation and impairment loss</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Laboratory and Manufacturing Equipment<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Furniture and<br/>Fixtures<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Computer Equipment and<br/>Software<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Leasehold Improvements<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Construction in<br/>process<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of January 1, 2018</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,360)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(175)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(534)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(807)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,876)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,032)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(60)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(296)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,088)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,476)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Disposals</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">114 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">74 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">20 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">210 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiaries</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassifications</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exchange differences</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">56 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">21 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">77 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of January 1, 2019</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,222)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(233)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(756)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,854)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,065)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,328)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(144)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(312)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,448)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,232)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Disposals</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">102 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">138 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">20 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">265 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiaries</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,457 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">53 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">319 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,829 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassifications</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(20)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exchange differences</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2019</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,968)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(239)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,030)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,955)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(7,192)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,572)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(215)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(297)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,860)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,944)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Disposals</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">576 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">40 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">616 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2020</span></td><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(3,965)</span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(454)</span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,287)</span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(4,815)</span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(10,520)</span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table> -2360000 -175000 -534000 -807000 0 -3876000 1032000 60000 296000 1088000 2476000 -114000 -2000 -74000 -20000 0 -210000 0 0 0 0 0 0 0 0 0 0 0 56000 0 0 21000 0 77000 -3222000 -233000 -756000 -1854000 0 -6065000 1328000 144000 312000 1448000 0 3232000 -102000 -138000 -5000 -20000 0 -265000 -1457000 0 -53000 -319000 0 -1829000 15000 0 -20000 6000 0 1000 8000 0 0 2000 0 10000 -2968000 -239000 -1030000 -2955000 0 -7192000 1572000 215000 297000 1860000 0 3944000 -576000 0 -40000 0 0 -616000 -3965000 -454000 -1287000 -4815000 0 -10520000 <table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:27.982%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Property and Equipment, net</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Laboratory and Manufacturing Equipment<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Furniture and<br/>Fixtures<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Computer Equipment and<br/>Software<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Leasehold Improvements<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Construction in<br/>process<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total<br/>$000s</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2019</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,417 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,213 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">478 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,701 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">646 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">21,455 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2020</span></td><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,456</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">998</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">232</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">13,239</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,852</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">22,777</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table> 4417000 1213000 478000 14701000 646000 21455000 4456000 998000 232000 13239000 3852000 22777000 3900000 3200000 2500000 Intangible Assets <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Intangible assets consist of licenses of intellectual property acquired by the Group through various agreements with third parties and are recorded at the value of the consideration transferred. Information regarding the cost and accumulated amortization of intangible assets is as follows:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:87.080%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.720%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Cost</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Licenses<br/>$000s</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of January 1, 2019</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,067 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">400 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiary</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,842)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2019</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">625 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">275 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2020</span></td><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">900</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:87.080%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.720%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Accumulated amortization</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Licenses<br/>$000s</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of January 1, 2019</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,987)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(117)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiary</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,104 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2019</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2020</span></td><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1)</span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:87.080%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.720%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Intangible assets, net</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Licenses<br/>$000s</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2019</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">625 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2020</span></td><td colspan="2" style="background-color:#ffffff;border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">899</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="background-color:#ffffff;border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">These intangible asset licenses represent in-process-research-and-development assets since they are still being developed and are not ready for their intended use. As such, these assets are not yet amortized but tested for impairment annually. The Company tested such assets for impairment as of balance sheet date and concluded that none were impaired. During the year ended December 31, 2019, Vor, Karuna and Gelesis were deconsolidated and as such $2.7 million in net assets were derecognized.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization expense was included in the Research and development expenses line item in the accompanying Consolidated Statements of Comprehensive Income/(Loss). Amortization expense, recorded using the straight-line method, was approximately $0.0 million, $0.1 million and $0.3 million for the years ended December 31, 2020, 2019 and 2018, respectively.</span></div> <table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:87.080%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.720%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Cost</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Licenses<br/>$000s</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of January 1, 2019</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,067 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">400 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiary</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,842)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2019</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">625 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">275 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2020</span></td><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">900</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table> 5067000 400000 -4842000 625000 275000 900000 <table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:87.080%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.720%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Accumulated amortization</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Licenses<br/>$000s</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of January 1, 2019</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,987)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(117)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiary</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,104 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2019</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2020</span></td><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1)</span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table> -1987000 -117000 -2104000 0 -1000 -1000 <table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:87.080%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.720%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Intangible assets, net</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Licenses<br/>$000s</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2019</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">625 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2020</span></td><td colspan="2" style="background-color:#ffffff;border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">899</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="background-color:#ffffff;border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table> 625000 899000 -2700000 0.0 100000 300000 Other Financial Assets <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other financial assets consist of restricted cash held, which represents amounts that are reserved as collateral against letters of credit with a bank that are issued for the benefit of a landlord in lieu of a security deposit for office space leased by the Group. Information regarding restricted cash was as follows: </span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31,</span></td><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Restricted cash</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,124</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,124 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total other financial assets</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,124</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,124 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div> <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other financial assets consist of restricted cash held, which represents amounts that are reserved as collateral against letters of credit with a bank that are issued for the benefit of a landlord in lieu of a security deposit for office space leased by the Group. Information regarding restricted cash was as follows: </span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31,</span></td><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Restricted cash</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,124</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,124 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total other financial assets</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,124</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,124 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div> 2124000 2124000 2124000 2124000 Equity <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total equity for PureTech as of December 31, 2020, and 2019 was as follows:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr style="height:17pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">December 31, 2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">December 31, 2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/></tr><tr style="height:11pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Equity</span></td><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share capital, £0.01 par value, issued and paid 285,885,025 and 285,370,619 as of December 31, 2020 and 2019, respectively</span></div></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,417</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,408 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Merger Reserve</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">138,506</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">138,506 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share premium</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">288,978</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">287,962 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Translation reserve</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">469</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other reserves</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(24,050)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(18,282)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Retained earnings/(accumulated deficit)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">260,429</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">254,444 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Equity attributable to owners of the Group</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">669,748</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">668,038 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-controlling interests</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(16,209)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(17,640)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total equity</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">653,539</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">650,398 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Changes in share capital and share premium relate primarily to incentive options exercises during the period.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Shareholders are entitled to vote on all matters submitted to shareholders for a vote. Each ordinary share is entitled to one vote. Each ordinary share is entitled to receive dividends when and if declared by the Company’s Directors. The Company has not declared any dividends in the past.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On June 18, 2015, the Company acquired the entire issued share capital of PureTech LLC in return for 159,648,387 Ordinary Shares. This was accounted for as a common control transaction at cost. It was deemed that the share capital was issued in line with movements in share capital as shown prior to the transaction taking place. In addition, the merger reserve records amounts previously recorded as share premium.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other reserves comprise the cumulative credit to share-based payment reserves corresponding to share-based payment expenses recognized through Consolidated Statements of Comprehensive Income/(Loss) as well as other additions that flow directly through equity such as the excess or deficit from changes in ownership of subsidiaries while control is maintained by the Group.</span></div> <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total equity for PureTech as of December 31, 2020, and 2019 was as follows:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr style="height:17pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">December 31, 2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">December 31, 2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/></tr><tr style="height:11pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Equity</span></td><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share capital, £0.01 par value, issued and paid 285,885,025 and 285,370,619 as of December 31, 2020 and 2019, respectively</span></div></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,417</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,408 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Merger Reserve</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">138,506</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">138,506 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share premium</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">288,978</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">287,962 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Translation reserve</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">469</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other reserves</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(24,050)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(18,282)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Retained earnings/(accumulated deficit)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">260,429</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">254,444 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Equity attributable to owners of the Group</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">669,748</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">668,038 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-controlling interests</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(16,209)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(17,640)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total equity</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">653,539</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">650,398 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div> 0.01 285885025 285370619 5417000 5408000 138506000 138506000 288978000 287962000 469000 0 -24050000 -18282000 260429000 254444000 669748000 668038000 -16209000 -17640000 653539000 650398000 159648387 Subsidiary Preferred Shares <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">IFRS 9 addresses the classification, measurement, and recognition of financial liabilities. Preferred shares issued by subsidiaries and affiliates often contain redemption and conversion features that are assessed under IFRS 9 in conjunction with the host preferred share instrument.This balance represents subsidiary preferred shares issued to third parties. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The subsidiary preferred shares are redeemable upon the occurrence of a contingent event, other than full liquidation of the Company, that is not considered to be within the control of the Company. Therefore these subsidiary preferred shares are classified as liabilities. These liabilities are measured at fair value through profit and loss. The preferred shares are convertible into ordinary shares of the subsidiaries at the option of the holder and mandatorily convertible into ordinary shares upon a subsidiary listing in a public market at a price above that specified in the subsidiary’s charter or upon the vote of the holders of subsidiary preferred shares specified in the charter. Under certain scenarios the number of ordinary shares receivable on conversion will change and therefore, the number of shares that will be issued is not fixed. As such the conversion feature is considered to be an embedded derivative that normally would require bifurcation. However, since the preferred share liabilities are measured at fair value through profit and loss no bifurcation is required. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The preferred shares are entitled to vote with holders of common shares on an as converted basis.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group recognizes the preferred share balance upon the receipt of cash financing or upon the conversion of notes into preferred shares at the amount received or carrying balance of any notes and derivatives converted into preferred shares.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The balance as of December 31, 2020 and 2019 represents the fair value of the instruments for all subsidiary preferred shares. The following summarizes the subsidiary preferred share balance:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31,</span></td><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,291</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,222 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">12,792</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,663 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">12,821</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,212 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta Biosciences</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">92,068</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">78,892 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total subsidiary preferred share balance</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">118,972</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100,989 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As is customary, in the event of any voluntary or involuntary liquidation, dissolution or winding up of a subsidiary, the holders of subsidiary preferred shares which are outstanding shall be entitled to be paid out of the assets of the subsidiary available for distribution to shareholders and before any payment shall be made to holders of ordinary shares. A merger, acquisition, sale of voting control or other transaction of a subsidiary in which the shareholders of the subsidiary immediately before the transaction do not own a majority of the outstanding shares of the surviving company shall be deemed to be a liquidation event. Additionally, a </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">sale, lease, transfer or other disposition of all or substantially all of the assets of the subsidiary shall also be deemed a liquidation event.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of December 31, 2020 and 2019, the minimum liquidation preference reflects the amounts that would be payable to the subsidiary preferred holders upon a liquidation event of the subsidiaries, which is as follows:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31,</span></td><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,216</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,216 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6,405</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,405 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">12,000</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,250 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta Biosciences</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86,161</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">77,161 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total minimum liquidation preference</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">106,782</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">93,032 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For the years ended December 31, 2020 and 2019 the Group recognized the following changes in the value of subsidiary preferred shares:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:87.080%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.720%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of January 1, 2019</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">217,519 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Adjustment to preferred shares due to adoption of IFRS 9</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Issuance of new preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">51,048 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Conversion of convertible notes</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,894 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Increase in value of preferred shares measured at fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">33,636 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance costs</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,458 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiary</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(207,346)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(108)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash Distribution</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(112)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as December 31, 2019 and January 1, 2020</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100,989 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Issuance of new preferred shares</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,750 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Increase in value of preferred shares measured at fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,234 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as December 31, 2020</span></td><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">118,972</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2020</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In January 2020 and April 2020, Sonde Health issued and sold shares of Series A-2 preferred shares for aggregate proceeds of $4.8 million, of which none was contributed by PureTech. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In April 2020 and July 2020, Vedanta issued and sold shares of Series C-2 preferred shares for aggregate proceeds of $9.0 million, of which none was contributed by PureTech.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2019</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On March 15, 2019, Karuna was deconsolidated. As of deconsolidation, the fair value of Karuna’s preferred share liability was $31.7 million.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On April 4, 2019, Sonde Health issued and sold shares of Series A-2 preferred shares for aggregate proceeds of $11.1 million, of which $5.3 million was contributed by outside investors. Approximately $5.8 million of outstanding principal and interest on convertible promissory notes issued by Sonde to PureTech converted into Series A-2 preferred shares in this financing in accordance with their terms. On August 29, 2019, Sonde sold an additional 1,052,632 shares of its Series A-2 preferred shares for aggregate proceeds of $2.0 million. It has been determined that these shares are liability classified and contain a liability classified embedded derivative. This embedded derivative is a conversion feature which can result in settlement in a variable number of shares. The instrument is not bifurcated and is measured in whole at fair value through the profit and loss.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In April 2019, Gelesis completed further closings of its Series 2 Growth financing issuing 799,894 shares for proceeds of $10.2 million, of which $8.6 million was contributed by outside investors and $1.7 million was contributed by PureTech.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In March and May 2019, Vedanta completed a second and third closing of its Series C preferred shares financing for aggregate proceeds of $18.7 million. PureTech Health did not participate in either closing. It has been determined that these shares are liability classified and contain a liability classified embedded derivative. This embedded derivative is a conversion feature which can result in settlement in a variable number of shares. The instrument is not bifurcated and is measured in whole at fair value through the profit and loss.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On July 1, 2019, Gelesis was deconsolidated. As of deconsolidation, the fair value of Gelesis’ preferred share liability was $175.6 million.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On July 19, 2019, all of the outstanding notes, plus accrued interest, issued by Follica converted into 17,639,204 shares of Series A-3 Preferred Shares and 14,200,044 shares of common share pursuant to a Series A-3 Note Conversion Agreement between Follica and the noteholders. Third parties held 2,422,990 A-3 preferred shares following the conversion. It has been determined that these shares are liability classified and contain a liability classified embedded derivative. This embedded derivative is a conversion feature which can result in settlement in a variable number of shares. The instrument is not bifurcated and is measured in whole at fair value through the profit and loss.</span></div>In September 2019, Vedanta received $16.6 million from outside investors through the issuance of its Series C-2 preferred shares in two separate closings. The issuances provided for the purchase of 711,772 Series C-2 shares at a purchase price of $23.38. PureTech Health did not participate in either closing. It has been determined that these shares are liability classified and contain a liability classified embedded derivative. This embedded derivative is a conversion feature which can result in settlement in a variable number of shares. The instrument is not bifurcated and is measured in whole at fair value through the profit and loss. The following summarizes the subsidiary preferred share balance:<table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31,</span></td><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,291</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,222 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">12,792</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,663 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">12,821</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,212 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta Biosciences</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">92,068</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">78,892 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total subsidiary preferred share balance</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">118,972</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100,989 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table> 1291000 3222000 12792000 11663000 12821000 7212000 92068000 78892000 118972000 100989000 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of December 31, 2020 and 2019, the minimum liquidation preference reflects the amounts that would be payable to the subsidiary preferred holders upon a liquidation event of the subsidiaries, which is as follows:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31,</span></td><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,216</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,216 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6,405</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,405 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">12,000</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,250 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta Biosciences</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86,161</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">77,161 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total minimum liquidation preference</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">106,782</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">93,032 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div> 2216000 2216000 6405000 6405000 12000000 7250000 86161000 77161000 106782000 93032000 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For the years ended December 31, 2020 and 2019 the Group recognized the following changes in the value of subsidiary preferred shares:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:87.080%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.720%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of January 1, 2019</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">217,519 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Adjustment to preferred shares due to adoption of IFRS 9</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Issuance of new preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">51,048 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Conversion of convertible notes</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,894 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Increase in value of preferred shares measured at fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">33,636 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance costs</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,458 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiary</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(207,346)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(108)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash Distribution</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(112)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as December 31, 2019 and January 1, 2020</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100,989 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Issuance of new preferred shares</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,750 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Increase in value of preferred shares measured at fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,234 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as December 31, 2020</span></td><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">118,972</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> 217519000 0 51048000 4894000 33636000 1458000 -207346000 -108000 -112000 100989000 13750000 4234000 118972000 4800000 9000000.0 -31700000 11100000 5300000 5800000 1052632 2000000.0 799894 10200000 8600000 1700000 18700000 -175600000 17639204 14200044 2422990 16600000 711772 23.38 Financial Instruments <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s financial instruments consist of financial liabilities, including preferred shares, convertible notes, warrants and loans payable, as well as financial assets classified as assets held at fair value.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair Value Process</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For financial instruments measured at fair value under IFRS 9 the change in the fair value is reflected through profit and loss. Using the guidance in IFRS 13, the total business enterprise value and allocatable equity of each entity within the Group was determined using a discounted cash flow income approach, replacement cost/asset approach, market scenario approach, or market backsolve approach through a recent arm’s length financing round. The approaches, in order of strongest fair value evidence, are detailed as follows:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:17.562%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:80.238%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Valuation Method</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Description</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Market – Backsolve</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The market backsolve approach benchmarks the original issue price (OIP) of the company’s latest funding transaction as current value.</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Market – Scenario</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The market scenario method is based on guideline transaction prices and multiples of similar public and private companies in initial public offerings and mergers and acquisitions. </span></td></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income Based – DCF</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The income approach is used to estimate fair value based on the income streams, such as cash flows or earnings, that an asset or business can be expected to generate.</span></td></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Asset/Cost</span></td><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The asset/cost approach considers reproduction or replacement cost as an indicator of value. </span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the years ended December 31, 2020 and 2019 at each measurement date, the total fair value of preferred shares, warrants and convertible note instruments, including embedded conversion rights that are not bifurcated, was determined using the following allocation methods: option pricing model (“OPM”), probability-weighted expected return method (“PWERM”) or Hybrid allocation framework. The methods are detailed as follows:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:17.562%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:80.238%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Allocation Method</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Description</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">OPM</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The OPM model treats preferred stock as call options on the enterprise’s equity value, with exercise prices based on the liquidation preferences of the preferred stock. </span></td></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Current Value </span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The enterprise value determined as of the valuation date is allocated to different classes of security based upon their rights and preferences.</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Common Stock Equivalent</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Every share is treated equally and the equity value derived is allocated assuming full conversion of preferred shares into common stock at the applicable conversion rate.</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PWERM</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Under a PWERM, share value is based upon the probability-weighted present value of expected future investment returns, considering each of the possible future outcomes available to the enterprise, as well as the rights of each share class. </span></td></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Hybrid</span></td><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The hybrid method (“HM”) is a combination of the PWERM and OPM. Under the hybrid method, multiple liquidity scenarios are weighted based on the probability of the scenarios occurrence, similar to the PWERM, while also utilizing the OPM to estimate the allocation of value in one or more of the scenarios. </span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Valuation policies and procedures are regularly monitored by the Company’s finance group. Fair value measurements, including those categorized within Level 3, are prepared and reviewed on their issuance date and then on an annual basis and any third-party valuations are reviewed for reasonableness and compliance with the fair value measurements guidance under IFRS. The Group measures fair values using the following fair value hierarchy that reflects the significance of the inputs used in making the measurements:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:17.562%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:80.238%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Fair Value<br/>Hierarchy Level</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Description</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Level 1</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Inputs that are quoted market prices (unadjusted) in active markets for identical instruments.</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Level 2</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Inputs other than quoted prices included within Level 1 that are observable either directly (i.e. as prices) or indirectly (i.e. derived from prices). </span></td></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Level 3</span></td><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Inputs that are unobservable. This category includes all instruments for which the valuation technique includes inputs not based on observable data and the unobservable inputs have a significant effect on the instrument’s valuation. </span></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Whilst the Group considers the methodologies and assumptions adopted in fair value measurements as supportable, reasonable and robust, because of the inherent uncertainty of valuation, those estimated values may differ significantly from the values that would have been used had a ready market for the investment existed and the differences could be significant.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">COVID-19 Consideration</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">At December 31, 2020, the Group assessed certain key assumptions within the valuation of its unquoted instruments and considered the impact of the COVID-19 pandemic on all unobservable inputs (Level 3). The assumptions considered with respect to COVID-19 included but were not limited to the following: exit scenarios and timing, discount rates, revenue assumptions as well as volatilities. The Group views any impact of the COVID-19 pandemic on its unquoted instruments as immaterial as of December 31, 2020. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary Preferred Shares Liability and Subsidiary Convertible Notes</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes the changes in the Group’s subsidiary preferred shares and convertible note liabilities measured at fair value, which were categorized as Level 3 in the fair value hierarchy:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"><div style="margin-bottom:10pt"><span><br/></span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Subsidiary Preferred Shares<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Subsidiary Convertible<br/>Notes<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1, 2018</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">215,635 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,343 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Value at issuance</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">54,537 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,824 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Conversion</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,930 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(7,581)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(36,517)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(24,066)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(128)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at December 31, 2018 and January 1, 2019</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">217,519 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,458 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Value at issuance</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">51,048 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,607 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Conversion to preferred</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,894 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,894)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Conversion to common</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,418)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(207,346)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5,017)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">33,636 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,389 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance Costs</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,458 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(112)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash distribution</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(108)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at December 31, 2019 and January 1, 2020</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100,989 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">125 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Value at issuance</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,750 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">25,000</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,234 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance at December 31, 2020</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">118,972</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">25,125</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The change in fair value of preferred shares and convertible notes are recorded in Finance income/(costs) – fair value accounting in the Consolidated Statements of Comprehensive Income/(Loss).</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The table below sets out information about the significant unobservable inputs used at December 31, 2020 in the fair value measurement of the Group’s material subsidiary preferred shares liabilities categorized as Level 3 in the fair value hierarchy:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:21.139%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.540%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:21.139%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.540%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:21.142%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Fair Value at</span></div><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">December 31, 2020</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Valuation Technique</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Unobservable Inputs</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Weighted Average</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Sensitivity to Decrease in Input</span></td></tr><tr style="height:11pt"><td colspan="3" rowspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">92,068</span></td><td colspan="3" rowspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Market – Backsolve &amp; Hybrid allocation</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Estimated time to exit</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.88</span></td><td colspan="3" rowspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:middle"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair value increase</span></td></tr><tr style="height:11pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Discount rate</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">30.0%</span></td></tr><tr style="height:11pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Volatility</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">95.0%</span></td></tr><tr style="height:11pt"><td colspan="3" rowspan="4" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,083</span></td><td colspan="3" rowspan="4" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income – DCF &amp; OPM allocation</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Estimated time to exit</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.89</span></td><td colspan="3" rowspan="2" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:middle"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair value increase</span></td></tr><tr style="height:11pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Discount rate</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19.7%</span></td></tr><tr style="height:11pt"><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Terminal value growth rate</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2.8)%</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair value decrease</span></td></tr><tr style="height:11pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Volatility</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">56.8%</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair value increase</span></td></tr><tr style="height:11pt"><td colspan="3" rowspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">12,821</span></td><td colspan="3" rowspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cost Approach &amp; OPM allocation</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Estimated time to exit</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.00</span></td><td colspan="3" rowspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:middle"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair value increase</span></td></tr><tr style="height:11pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Discount rate</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">29.4%</span></td></tr><tr style="height:11pt"><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Volatility</span></td><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">40.0%</span></td></tr></table></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary Preferred Shares Sensitivity </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following summarizes the sensitivity from the assumptions made by the Company with respect to the significant unobservable inputs which are categorized as Level 3 in the fair value hierarchy and used in the fair value measurement of the Group’s subsidiary preferred shares liabilities, as well as that with respect to the enterprise value of the underlying subsidiary in general (Please refer to Note 15):</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.566%"><tr><td style="width:1.0%"/><td style="width:63.697%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.501%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.502%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Input</span></td><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Subsidiary Preferred Share Liability</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31, 2020</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Sensitivity Range</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Financial Liability Increase/(Decrease)<br/>$000s</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr style="height:11pt"><td colspan="3" rowspan="4" style="background-color:#fdfdfd;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary Enterprise Value</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">-2 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,146)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr style="height:11pt"><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+2%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,194 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr style="height:11pt"><td colspan="3" rowspan="2" style="background-color:#fdfdfd;border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Time to Liquidity</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#ffffff;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">'</span><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">-6 Months</span></div></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,815 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr style="height:11pt"><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#ffffff;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">'</span><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+6 Months</span></div></td><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5,437)</span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.566%"><tr><td style="width:1.0%"/><td style="width:63.697%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.501%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.502%"/><td style="width:0.1%"/></tr><tr style="height:11pt"><td colspan="3" rowspan="2" style="background-color:#fdfdfd;border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Discount Rate</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">-5 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">12,227 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr style="height:11pt"><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+5%</span></td><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5,779)</span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial Assets Held at Fair Value</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Karuna Valuation</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Karuna (Nasdaq: KRTX) is a listed entity on an active exchange and as such the fair value for the year ended December 31, 2020 was calculated utilizing the quoted common share price. Please refer to Note 5 for further details.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Akili, Gelesis and Vor Valuation</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In accordance with IFRS 9, the Company accounts for its preferred share investments in Akili, Gelesis and Vor as financial assets held at fair value through the profit and loss. During the year ended December 31, 2020, the Company recorded its investment at fair value and recognized a gain of $41.3 million that was recorded to the Consolidated Statements of Comprehensive Income/(Loss) on the line item Gain/(loss) on investments held at fair value.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes the changes in the Group’s investments held at fair value, which were categorized as Level 3 in the fair value hierarchy:</span></div><div style="margin-bottom:6pt;text-align:justify"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:87.080%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.720%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$'000s</span></td><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1, 2018</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,449 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of Akili</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">70,748 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(Loss) on changes in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">12,966 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at December 31, 2018 and January 1, 2019</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">85,163 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of Vor</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">12,028 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of Karuna</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">77,373 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of Gelesis</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">49,170 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclass of Karuna to Associate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(118,006)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(Loss) on changes in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">48,867 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Issuance of note receivable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,480 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Conversion of note receivable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,630)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at December 31, 2019 and January 1, 2020</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">154,445 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash purchase of Gelesis preferred shares (please refer to Note 6)</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,000 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash purchase of Vor preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,150 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(Loss) on changes in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41,297 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2020 before allocation of associate gain/(loss) to long-term interest</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">206,892</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of associate loss allocated to long-term interest (please refer to Note 6)</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(23,006)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2020 after allocation of associate gain/(loss) to long-term interest</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">183,886</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The change in fair value of investments held at fair value are recorded in Gain/(loss) on investments held at fair value in the Consolidated Statements of Comprehensive Income/(Loss).</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The table below sets out information about the significant unobservable inputs used at December 31, 2020 in the fair value measurement of the Group’s material investments held at fair value categorized as Level 3 in the fair value hierarchy:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:21.139%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.540%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:21.139%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.540%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:21.142%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Fair Value at</span></div><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">December 31, 2020</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Valuation Technique</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Unobservable Inputs</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Weighted Average</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Sensitivity to Decrease in Input</span></td></tr><tr style="height:11pt"><td colspan="3" rowspan="5" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">204,379</span></td><td colspan="3" rowspan="5" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Market – Scenario &amp; Hybrid allocation</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Estimated time to exit</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.73</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair value increase</span></td></tr><tr style="height:11pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exit valuation multiples</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.19</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair value decrease</span></td></tr><tr style="height:11pt"><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Discount rate</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.0%</span></td><td colspan="3" rowspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:middle"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair value increase</span></td></tr><tr style="height:23pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Discount for lack of marketability ("DLOM")</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10.0%</span></td></tr><tr style="height:11pt"><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Volatility</span></td><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">65.0%</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following summarizes the sensitivity from the assumptions made by the Company with respect to the significant unobservable inputs which are categorized as Level 3 in the fair value hierarchy and used in the fair value measurement of the Group’s investments held at fair value, as well as that with respect to the enterprise value of the underlying investee in general (Please refer to Note 5):</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.566%"><tr><td style="width:1.0%"/><td style="width:63.697%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.501%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.502%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Input</span></td><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Investments Held at Fair Value</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31, 2020</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Sensitivity Range</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Financial Asset Increase/ (Decrease)<br/>$000s</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr style="height:11pt"><td colspan="3" rowspan="4" style="background-color:#fdfdfd;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investee Enterprise Value</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">-2 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,915)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr style="height:11pt"><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+2%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,886 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr style="height:11pt"><td colspan="3" rowspan="2" style="background-color:#fdfdfd;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Time to Liquidity</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#ffffff;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">'</span><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">-6 Months</span></div></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22,828 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr style="height:11pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#ffffff;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">'</span><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+6 Months</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(20,005)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr style="height:11pt"><td colspan="3" rowspan="2" style="background-color:#fdfdfd;border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Discount Rate</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">-5 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,691 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr style="height:11pt"><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+5%</span></td><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10,689)</span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Warrants</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Warrants issued by subsidiaries within the Group are classified as liabilities, as they will be settled in a variable number of shares and are not fixed-for-fixed. The following table summarizes the changes in the Group’s subsidiary warrant liabilities, which were categorized as Level 3 in the fair value hierarchy:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.265%"><tr><td style="width:1.0%"/><td style="width:87.025%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Subsidiary Warrant Liability<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1, 2018</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,095 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(83)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at December 31, 2018 and January 1, 2019</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,012 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Warrant Issuance</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,706 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis Deconsolidation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(21,611)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,890 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at December 31, 2019 and January 1, 2020</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,997 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Warrant Issuance</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">92 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">117 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance at December 31, 2020</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,206</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The change in fair value of warrants are recorded in Finance income/(costs) – fair value accounting in the Consolidated Statements of Comprehensive Income/(Loss).</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In June 2019, Gelesis amended their existing license and patent agreement with One S.r.l. As a result of the amendment Gelesis issued One S.r.l. a warrant equal to 2.7 percent of as converted shares following the next financing round. The fair value of the warrant was $4.7 million at issuance. On July 1, 2019, Gelesis deconsolidated and warrant liability of $21.6 million relating to Series A-1, A-3, A-4 and One S.r.l. warrants was derecognized. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In connection with various amendments to its 2010 Loan and Security Agreement, Follica issued Series A-1 preferred share warrants at various dates in 2013 and 2014. Each of the warrants has an exercise price of $0.14 and a contractual term of ten years from the date of issuance. In 2017, in conjunction with the issuance of convertible notes, the exercise price of the warrants was adjusted to $0.07 per share. The change in the fair value of the subsidiary warrants was recorded in finance costs, net in the Consolidated Statements of Comprehensive Income/(Loss). The $8.2 million warrant liability at December 31, 2020 was largely attributable to the outstanding Follica preferred share warrants.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In connection with the September 2, 2020 Oxford Finance LLC loan issuance, Vedanta also issued Oxford Finance LLC 12,886 Series C-2 preferred share warrants with an exercise price of $23.28 per share, expiring September 2030.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The table below sets out the weighted average of significant unobservable inputs used at December 31, 2020 with respect to determining the fair value of the Group's warrants categorized as Level 3 in the fair value hierarchy:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:87.080%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.720%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Assumption/Input</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Warrants</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected term</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.65</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected volatility</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">54.9 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Risk free interest rate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected dividend yield</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Estimated fair value of the convertible preferred shares</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$3.09</span></td></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exercise price of the warrants</span></td><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$0.27</span></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following summarizes the sensitivity from the assumptions made by the Company with respect to the significant unobservable inputs which are categorized as Level 3 in the fair value hierarchy and used in the fair value measurement of the Group’s warrant liabilities:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.566%"><tr><td style="width:1.0%"/><td style="width:63.697%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.501%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.502%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Input</span></td><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Warrant Liability</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As at December 31</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Sensitivity Range</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Financial Liability Increase/(Decrease)<br/>$000s</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr style="height:11pt"><td colspan="3" rowspan="2" style="background-color:#fdfdfd;border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Discount Rate</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">-5 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,279 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr style="height:11pt"><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+5%</span></td><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,321)</span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair Value Measurement and Classification</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The fair value of financial instruments by category at December 31, 2020 and 2019:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:27.360%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="21" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Carrying Amount</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="12" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Fair Value</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Financial Assets<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Financial Liabilities<br/>$000s</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Level 1<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Level 2<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Level 3<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Total<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Financial assets:</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">U.S. treasuries</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Money Markets</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">394,143</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">394,143</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">394,143</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investments held at fair value</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">3</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">553,167</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">346,275</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">206,892</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">553,167</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:27.360%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other receivables</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">4</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,558</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,558</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,558</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total financial assets</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">949,867</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">740,417</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,558</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">206,892</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">949,867</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Financial liabilities:</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary warrant liability</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,206</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,206</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,206</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">118,972</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">118,972</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">118,972</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary notes payable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">26,455</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,330</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">25,125</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">26,455</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total financial liabilities</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">153,633</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,330</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">152,303</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">153,633</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Issued by governments and government agencies, as applicable, all of which are investment grade.</span></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Issued by a diverse group of corporations, largely consisting of financial institutions, virtually all of which are investment grade.</span></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">3    Balance prior to share of associate loss allocated to long-term interest (please refer to Note 6).</span></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">4    Outstanding receivables are owed primarily by corporations and government agencies, virtually all of which are investment grade.</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:27.360%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="21" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></td></tr><tr><td colspan="3" style="padding:0 1pt"><div style="margin-bottom:10pt"><span><br/></span></div></td><td colspan="6" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Carrying Amount</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="12" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Fair Value</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Financial Assets<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Financial Liabilities<br/>$000s</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Level 1<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Level 2<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Level 3<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial assets:</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">U.S. treasuries</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">30,088 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">30,088 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">30,088 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Money Markets</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">106,586 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">106,586 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">106,586 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investments held at fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">714,905 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">560,460 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">154,445 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">714,905 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Loans and receivables:</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other receivables</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">3</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,977 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,977 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,977 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total financial assets</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">853,556 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">697,134 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,977 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">154,445 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">853,556 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial liabilities:</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary warrant liability</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,997 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,997 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,997 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100,989 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100,989 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100,989 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary notes payable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,455 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,455 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,455 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total financial liabilities</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">110,441 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,455 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">108,986 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">110,441 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Issued by governments and government agencies, as applicable, all of which are investment grade.</span></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Issued by a diverse group of corporations, largely consisting of financial institutions, virtually all of which are investment grade.</span></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">3    Outstanding receivables are owed primarily by corporations and government agencies, virtually all of which are investment grade.</span></div> <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary Preferred Shares Liability and Subsidiary Convertible Notes</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes the changes in the Group’s subsidiary preferred shares and convertible note liabilities measured at fair value, which were categorized as Level 3 in the fair value hierarchy:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"><div style="margin-bottom:10pt"><span><br/></span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Subsidiary Preferred Shares<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Subsidiary Convertible<br/>Notes<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1, 2018</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">215,635 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,343 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Value at issuance</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">54,537 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,824 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Conversion</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,930 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(7,581)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(36,517)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(24,066)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(128)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at December 31, 2018 and January 1, 2019</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">217,519 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,458 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Value at issuance</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">51,048 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,607 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Conversion to preferred</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,894 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,894)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Conversion to common</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,418)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(207,346)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5,017)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">33,636 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,389 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance Costs</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,458 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(112)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash distribution</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(108)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at December 31, 2019 and January 1, 2020</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100,989 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">125 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Value at issuance</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,750 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">25,000</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,234 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance at December 31, 2020</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">118,972</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">25,125</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> 215635000 11343000 54537000 5824000 7930000 -7581000 -36517000 0 -24066000 -128000 217519000 9458000 51048000 1607000 4894000 -4894000 0 -2418000 -207346000 -5017000 33636000 1389000 1458000 0 -112000 0 -108000 0 100989000 125000 13750000 25000000 4234000 0 118972000 25125000 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The table below sets out information about the significant unobservable inputs used at December 31, 2020 in the fair value measurement of the Group’s material subsidiary preferred shares liabilities categorized as Level 3 in the fair value hierarchy:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:21.139%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.540%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:21.139%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.540%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:21.142%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Fair Value at</span></div><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">December 31, 2020</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Valuation Technique</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Unobservable Inputs</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Weighted Average</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Sensitivity to Decrease in Input</span></td></tr><tr style="height:11pt"><td colspan="3" rowspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">92,068</span></td><td colspan="3" rowspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Market – Backsolve &amp; Hybrid allocation</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Estimated time to exit</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.88</span></td><td colspan="3" rowspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:middle"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair value increase</span></td></tr><tr style="height:11pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Discount rate</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">30.0%</span></td></tr><tr style="height:11pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Volatility</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">95.0%</span></td></tr><tr style="height:11pt"><td colspan="3" rowspan="4" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,083</span></td><td colspan="3" rowspan="4" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income – DCF &amp; OPM allocation</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Estimated time to exit</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.89</span></td><td colspan="3" rowspan="2" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:middle"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair value increase</span></td></tr><tr style="height:11pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Discount rate</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19.7%</span></td></tr><tr style="height:11pt"><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Terminal value growth rate</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2.8)%</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair value decrease</span></td></tr><tr style="height:11pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Volatility</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">56.8%</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair value increase</span></td></tr><tr style="height:11pt"><td colspan="3" rowspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">12,821</span></td><td colspan="3" rowspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cost Approach &amp; OPM allocation</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Estimated time to exit</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.00</span></td><td colspan="3" rowspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:middle"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair value increase</span></td></tr><tr style="height:11pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Discount rate</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">29.4%</span></td></tr><tr style="height:11pt"><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Volatility</span></td><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">40.0%</span></td></tr></table></div> 92068000 0.88 0.300 0.950 14083000 2.89 0.197 -0.028 0.568 12821000 2.00 0.294 0.400 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following summarizes the sensitivity from the assumptions made by the Company with respect to the significant unobservable inputs which are categorized as Level 3 in the fair value hierarchy and used in the fair value measurement of the Group’s subsidiary preferred shares liabilities, as well as that with respect to the enterprise value of the underlying subsidiary in general (Please refer to Note 15):</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.566%"><tr><td style="width:1.0%"/><td style="width:63.697%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.501%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.502%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Input</span></td><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Subsidiary Preferred Share Liability</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31, 2020</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Sensitivity Range</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Financial Liability Increase/(Decrease)<br/>$000s</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr style="height:11pt"><td colspan="3" rowspan="4" style="background-color:#fdfdfd;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary Enterprise Value</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">-2 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,146)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr style="height:11pt"><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+2%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,194 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr style="height:11pt"><td colspan="3" rowspan="2" style="background-color:#fdfdfd;border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Time to Liquidity</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#ffffff;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">'</span><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">-6 Months</span></div></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,815 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr style="height:11pt"><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#ffffff;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">'</span><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+6 Months</span></div></td><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5,437)</span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.566%"><tr><td style="width:1.0%"/><td style="width:63.697%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.501%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.502%"/><td style="width:0.1%"/></tr><tr style="height:11pt"><td colspan="3" rowspan="2" style="background-color:#fdfdfd;border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Discount Rate</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">-5 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">12,227 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr style="height:11pt"><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+5%</span></td><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5,779)</span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table> -0.02 -2146000 0.02 2194000 P6M 5815000 P6M -5437000 -0.05 12227000 0.05 -5779000 41300000 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes the changes in the Group’s investments held at fair value, which were categorized as Level 3 in the fair value hierarchy:</span></div><div style="margin-bottom:6pt;text-align:justify"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:87.080%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.720%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$'000s</span></td><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1, 2018</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,449 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of Akili</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">70,748 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(Loss) on changes in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">12,966 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at December 31, 2018 and January 1, 2019</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">85,163 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of Vor</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">12,028 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of Karuna</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">77,373 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of Gelesis</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">49,170 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclass of Karuna to Associate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(118,006)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(Loss) on changes in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">48,867 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Issuance of note receivable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,480 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Conversion of note receivable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,630)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at December 31, 2019 and January 1, 2020</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">154,445 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash purchase of Gelesis preferred shares (please refer to Note 6)</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,000 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash purchase of Vor preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,150 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(Loss) on changes in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41,297 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2020 before allocation of associate gain/(loss) to long-term interest</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">206,892</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of associate loss allocated to long-term interest (please refer to Note 6)</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(23,006)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2020 after allocation of associate gain/(loss) to long-term interest</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">183,886</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div> 1449000 70748000 12966000 85163000 12028000 77373000 49170000 -118006000 48867000 6480000 -6630000 154445000 10000000 1150000 41297000 206892000 -23006000 183886000 <table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:21.139%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.540%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:21.139%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.540%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:21.142%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Fair Value at</span></div><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">December 31, 2020</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Valuation Technique</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Unobservable Inputs</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Weighted Average</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Sensitivity to Decrease in Input</span></td></tr><tr style="height:11pt"><td colspan="3" rowspan="5" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">204,379</span></td><td colspan="3" rowspan="5" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Market – Scenario &amp; Hybrid allocation</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Estimated time to exit</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.73</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair value increase</span></td></tr><tr style="height:11pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exit valuation multiples</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.19</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair value decrease</span></td></tr><tr style="height:11pt"><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Discount rate</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.0%</span></td><td colspan="3" rowspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:middle"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair value increase</span></td></tr><tr style="height:23pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Discount for lack of marketability ("DLOM")</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10.0%</span></td></tr><tr style="height:11pt"><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Volatility</span></td><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">65.0%</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table> 204379000 1.73 2.19 0.280 0.100 0.650 <table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.566%"><tr><td style="width:1.0%"/><td style="width:63.697%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.501%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.502%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Input</span></td><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Investments Held at Fair Value</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31, 2020</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Sensitivity Range</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Financial Asset Increase/ (Decrease)<br/>$000s</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr style="height:11pt"><td colspan="3" rowspan="4" style="background-color:#fdfdfd;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investee Enterprise Value</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">-2 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,915)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr style="height:11pt"><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+2%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,886 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr style="height:11pt"><td colspan="3" rowspan="2" style="background-color:#fdfdfd;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Time to Liquidity</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#ffffff;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">'</span><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">-6 Months</span></div></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22,828 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr style="height:11pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#ffffff;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">'</span><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+6 Months</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(20,005)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr style="height:11pt"><td colspan="3" rowspan="2" style="background-color:#fdfdfd;border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Discount Rate</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">-5 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,691 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr style="height:11pt"><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+5%</span></td><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10,689)</span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table> -0.02 -3915000 0.02 3886000 P6M 22828000 P6M -20005000 -0.05 11691000 0.05 -10689000 <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Warrants</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Warrants issued by subsidiaries within the Group are classified as liabilities, as they will be settled in a variable number of shares and are not fixed-for-fixed. The following table summarizes the changes in the Group’s subsidiary warrant liabilities, which were categorized as Level 3 in the fair value hierarchy:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.265%"><tr><td style="width:1.0%"/><td style="width:87.025%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.775%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Subsidiary Warrant Liability<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1, 2018</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,095 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(83)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at December 31, 2018 and January 1, 2019</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,012 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Warrant Issuance</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,706 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis Deconsolidation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(21,611)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,890 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at December 31, 2019 and January 1, 2020</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,997 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Warrant Issuance</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">92 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">117 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance at December 31, 2020</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,206</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> 13095000 -83000 13012000 4706000 -21611000 11890000 7997000 92000 117000 8206000 0.027 4700000 -21600000 0.14 0.07 8200000 12886 23.28 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The table below sets out the weighted average of significant unobservable inputs used at December 31, 2020 with respect to determining the fair value of the Group's warrants categorized as Level 3 in the fair value hierarchy:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:87.080%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.720%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Assumption/Input</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Warrants</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected term</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.65</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected volatility</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">54.9 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Risk free interest rate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected dividend yield</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Estimated fair value of the convertible preferred shares</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$3.09</span></td></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exercise price of the warrants</span></td><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$0.27</span></td></tr></table></div> 2.65 0.549 0.001 0 3.09 0.27 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following summarizes the sensitivity from the assumptions made by the Company with respect to the significant unobservable inputs which are categorized as Level 3 in the fair value hierarchy and used in the fair value measurement of the Group’s warrant liabilities:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.566%"><tr><td style="width:1.0%"/><td style="width:63.697%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.501%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.502%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Input</span></td><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Warrant Liability</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As at December 31</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Sensitivity Range</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Financial Liability Increase/(Decrease)<br/>$000s</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr style="height:11pt"><td colspan="3" rowspan="2" style="background-color:#fdfdfd;border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Discount Rate</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">-5 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,279 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr style="height:11pt"><td colspan="3" style="border-bottom:1pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+5%</span></td><td colspan="2" style="border-bottom:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,321)</span></td><td style="border-bottom:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div> -0.05 7279000 0.05 -3321000 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The fair value of financial instruments by category at December 31, 2020 and 2019:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:27.360%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="21" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Carrying Amount</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="12" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Fair Value</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Financial Assets<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Financial Liabilities<br/>$000s</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Level 1<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Level 2<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Level 3<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Total<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Financial assets:</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">U.S. treasuries</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Money Markets</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">394,143</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">394,143</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">394,143</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investments held at fair value</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">3</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">553,167</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">346,275</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">206,892</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">553,167</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:27.360%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other receivables</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">4</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,558</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,558</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,558</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total financial assets</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">949,867</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">740,417</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,558</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">206,892</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">949,867</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Financial liabilities:</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary warrant liability</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,206</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,206</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,206</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">118,972</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">118,972</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">118,972</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary notes payable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">26,455</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,330</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">25,125</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">26,455</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total financial liabilities</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">153,633</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,330</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">152,303</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">153,633</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Issued by governments and government agencies, as applicable, all of which are investment grade.</span></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Issued by a diverse group of corporations, largely consisting of financial institutions, virtually all of which are investment grade.</span></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">3    Balance prior to share of associate loss allocated to long-term interest (please refer to Note 6).</span></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">4    Outstanding receivables are owed primarily by corporations and government agencies, virtually all of which are investment grade.</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:27.360%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="21" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></td></tr><tr><td colspan="3" style="padding:0 1pt"><div style="margin-bottom:10pt"><span><br/></span></div></td><td colspan="6" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Carrying Amount</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="12" style="border-top:1pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Fair Value</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Financial Assets<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Financial Liabilities<br/>$000s</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Level 1<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Level 2<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Level 3<br/>$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial assets:</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">U.S. treasuries</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">30,088 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">30,088 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">30,088 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Money Markets</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">106,586 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">106,586 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">106,586 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investments held at fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">714,905 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">560,460 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">154,445 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">714,905 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Loans and receivables:</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other receivables</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">3</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,977 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,977 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,977 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total financial assets</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">853,556 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">697,134 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,977 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">154,445 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">853,556 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial liabilities:</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary warrant liability</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,997 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,997 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,997 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100,989 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100,989 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100,989 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary notes payable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,455 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,455 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,455 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total financial liabilities</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">110,441 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,455 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">108,986 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">110,441 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Issued by governments and government agencies, as applicable, all of which are investment grade.</span></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Issued by a diverse group of corporations, largely consisting of financial institutions, virtually all of which are investment grade.</span></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">3    Outstanding receivables are owed primarily by corporations and government agencies, virtually all of which are investment grade.</span></div> 0 0 0 0 0 394143000 394143000 0 0 394143000 553167000 346275000 0 206892000 553167000 2558000 0 2558000 0 2558000 949867000 740417000 2558000 206892000 949867000 8206000 0 0 8206000 8206000 118972000 0 0 118972000 118972000 26455000 0 1330000 25125000 26455000 153633000 0 1330000 152303000 153633000 30088000 30088000 0 0 30088000 106586000 106586000 0 0 106586000 714905000 560460000 0 154445000 714905000 1977000 0 1977000 0 1977000 853556000 697134000 1977000 154445000 853556000 7997000 0 0 7997000 7997000 100989000 0 0 100989000 100989000 1455000 0 1455000 0 1455000 110441000 0 1455000 108986000 110441000 Subsidiary Notes Payable <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The subsidiary notes payable are comprised of loans and convertible notes. During the years ended December 31, 2020 and 2019, the financial instruments for Knode and Appeering did not contain embedded derivatives and therefore these instruments continue to be held at amortized cost. The notes payable consist of the following:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">December 31,</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Loans</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,330</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,330 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Convertible notes</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">25,125</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">125 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total subsidiary notes payable</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">26,455</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,455 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Loans</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In October 2010, Follica entered into a loan and security agreement with Lighthouse Capital Partners VI, L.P. The loan is secured by Follica’s assets, including Follica’s intellectual property and bears interest at a rate of 12.0 percent. The outstanding loan balance totaled approximately $1.3 million and $1.3 million as of December 31, 2020 and 2019. The accrued interest on such loan balance is presented as Other current liabilities and totaled approximately $0.5 million and $0.4 million as of December 31, 2020 and 2019, respectively.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Convertible Notes</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Convertible Notes outstanding were as follows:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:27.982%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:0 1pt"><div style="margin-bottom:10pt"><span><br/></span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Karuna</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Follica</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Vedanta</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Knode</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Appeering</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="24" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">January 1, 2019</span></div></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,838 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,495 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">50 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">75 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,458 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gross principal</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,607 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,607 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">572 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">817 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,389 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Conversion to preferred</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,894)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="3" style="display:none"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,894)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Conversion to common</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,418)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="3" style="display:none"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,418)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5,017)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="3" style="display:none"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5,017)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">December 31, 2019 and January 1, 2020</span></div></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">50 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">75 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">125 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gross principal</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">25,000 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">25,000 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">December 31, 2020</span></div></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">25,000</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">50</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">75</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">25,125</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On March 15, 2019, Karuna was deconsolidated in conjunction with the closing of a Series B Preferred Stock financing and the outstanding convertible note liability of $5.0 million was derecognized. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In May 2017 and September 2017, Follica received $0.5 million and $0.6 million, respectively, from an existing third-party investor through the issuance of convertible notes. The notes bore interest at an annual rate of 10.0 percent, matured 30 days after demand by the holder, were convertible into equity upon a qualifying financing event, and required payment of at least five times the outstanding principal and accrued interest upon a change of control transaction. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On July 19, 2019, all of the outstanding notes, plus accrued interest, issued by Follica converted into 17,639,204 shares of Series A-3 Preferred Stock and 14,200,044 shares of common shares pursuant to a Series A-3 Note Conversion Agreement between Follica and the noteholders. Third parties held 2,422,990 A-3 preferred shares and 1,981,944 common shares following the conversion. The preferred shares are classified as financial liabilities at fair value through the profit and loss. The common shares are accounted for as Non-controlling interests. See Note 18 for further details on such change in non-controlling interests.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On December 30, 2020, Vedanta issued a $25.0 million convertible promissory note to an investor. The note bears interest at an annual rate of 6.0 percent and matures on the first anniversary of the note. Prepayment of the note is not allowed and there is no conversion discount feature on the note. The note mandatorily converts in a Qualified equity financing and a Qualified Public Offering at the current price of the financing or offering, all as defined in the note purchase agreement. In addition, the note allows for optional conversion immediately prior to a Non Qualified public offering, Non Qualified Equity financing, or a Corporate transaction. In the case of a Non qualified financing or a Corporate transaction the note will convert to the preferred shares issued at the time of the last financing round at the price at such financing round. In the event of no conversion prior to a change in control transaction, the note is repaid at one and a half times the outstanding principal plus accrued interest.</span></div> The notes payable consist of the following:<table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">December 31,</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Loans</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,330</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,330 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Convertible notes</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">25,125</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">125 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total subsidiary notes payable</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">26,455</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,455 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table> 1330000 1330000 25125000 125000 26455000 1455000 0.120 1300000 1300000 500000 400000 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Convertible Notes outstanding were as follows:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:27.982%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:0 1pt"><div style="margin-bottom:10pt"><span><br/></span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Karuna</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Follica</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Vedanta</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Knode</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Appeering</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="24" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">January 1, 2019</span></div></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,838 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,495 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">50 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">75 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,458 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gross principal</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,607 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,607 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">572 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">817 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,389 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Conversion to preferred</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,894)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="3" style="display:none"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,894)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Conversion to common</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,418)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="3" style="display:none"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,418)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5,017)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="3" style="display:none"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5,017)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">December 31, 2019 and January 1, 2020</span></div></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">50 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">75 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">125 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gross principal</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">25,000 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">25,000 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">December 31, 2020</span></div></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">25,000</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">50</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">75</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">25,125</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> 2838000 6495000 0 50000 75000 9458000 1607000 0 0 0 0 1607000 572000 817000 0 0 0 1389000 0 -4894000 0 0 0 -4894000 0 -2418000 0 0 0 -2418000 -5017000 0 0 0 0 -5017000 0 0 0 50000 75000 125000 0 0 25000000 0 0 25000000 0 0 0 0 0 0 0 0 25000000 50000 75000 25125000 -5000000.0 500000 600000 0.100 17639204 14200044 2422990 1981944 25000000.0 0.060 Non-Controlling Interest <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the year ended December 31, 2019, the Company deconsolidated three of its subsidiaries which resulted in a change to the composition of its reportable segments. The Company has revised in the 2019 financial statements the 2018 financial information to conform to the presentation as of and for the period ending December 31, 2019. Please refer to Note 4 “Segment Information” for further details regarding reportable segments.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes the changes in the equity classified non-controlling ownership interest in subsidiaries by reportable segment:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:39.802%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.722%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Internal</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Controlled Founded Entities</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Non-Controlled Founded<br/>Entities</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Parent Company &amp; Other<br/>$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total<br/>$000s</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1, 2018</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,484)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(18,869)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(125,758)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">525 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(145,586)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of comprehensive loss</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(7,315)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10,710)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,980)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(27,005)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiary</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">55,168 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">55,168 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Equity settled share-based payments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,476 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,345 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">67 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,888 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at December 31, 2018 and January 1, 2019</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,799)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(27,103)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(73,225)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">592 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(108,535)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of comprehensive loss</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15,264)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15,862)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(23,953)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(55,079)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiary</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">97,178 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">97,178 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary note conversion and changes in NCI ownership interest</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">23,049 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">23,049 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Equity settled share-based payments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,683 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,683 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Purchase of minority interest</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">24,039 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">24,039 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">24 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">25 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at December 31, 2019 and January 1, 2020</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(18,233)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">593 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(17,640)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of comprehensive loss</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,402)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,417)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Equity settled share-based payments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,822 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,822 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">30 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">24 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2020</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(16,783)</span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">573</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(16,210)</span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following tables summarize the financial information related to the Group’s subsidiaries with material non-controlling interests, aggregated for interests in similar entities, and before and after intra group eliminations.</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:39.802%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.722%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the year ended December 31</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Internal<br/>$000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Controlled Founded Entities<br/>$000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Non-Controlled Founded<br/>Entities<br/>$000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Intra-group eliminations</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Total</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Statement of Comprehensive Loss</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total revenue</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,224</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,224</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) for the year</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(55,942)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,073</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(54,869)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other comprehensive income/(loss)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total comprehensive income/(loss) for the year</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(55,942)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,073</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(54,869)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Statement of Financial Position</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">68,346</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(7)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">68,339</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total liabilities</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">200,430</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(14,621)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">185,809</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Net assets/(liabilities)</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(132,084)</span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14,615</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(117,470)</span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of December 31, 2020, Controlled Founded Entities with non-controlling interests primarily include Alivio Therapeutics, Inc., Follica Incorporated, Sonde Health Inc., and Vedanta Biosciences, Inc. Ownership interests of the non-controlling interests in Alivio Therapeutics, Inc., Follica Incorporated, Sonde Health Inc., and Vedanta Biosciences, Inc are 8.1 percent, 19.9 percent, 4.5 percent and 0.4 percent, respectively. In addition, Non-controlling interests include the amounts recorded for subsidiary stock options, with the vast majority comprising of Vedanta stock options.</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the year ended December 31</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Internal<br/>$000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Controlled Founded Entities<br/> $000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Non-Controlled Founded<br/>Entities</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:4.55pt;font-weight:400;line-height:120%;position:relative;top:-2.44pt;vertical-align:baseline">1</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Statement of Comprehensive Loss</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,079 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,968 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) for the year</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(24,289)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(26,250)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(47,905)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other comprehensive income/(loss)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total comprehensive income/(loss) for the year</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(24,289)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(26,250)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(47,915)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Statement of Financial Position</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">17,614 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,290 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total liabilities</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,510 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">50,554 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net Liabilities</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,104 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(45,264)</span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Non-Controlled Founded Entities non-controlling interest calculation does not include equity method accounting, fair value method accounting or the gain on the deconsolidation of subsidiary related to Vor, Karuna, Gelesis, resTORbio or Akili, which is recorded within PureTech Health, LLC. Please refer to Note 5.</span></div><div style="margin-bottom:2pt"><span><br/></span></div><div style="margin-bottom:6pt;margin-top:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the year ended December 31</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Internal<br/>$000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Controlled Founded Entities<br/> $000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Non-Controlled Founded<br/>Entities</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:4.55pt;font-weight:400;line-height:120%;position:relative;top:-2.44pt;vertical-align:baseline">1</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Statement of Comprehensive Loss</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,195 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">18,504 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">20 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) for the year</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,454)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(26,206)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(41,239)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other comprehensive income/(loss)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(214)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(214)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total comprehensive income/(loss) for the year</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,454)</span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(26,420)</span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(41,453)</span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Non-Controlled Founded Entities non-controlling interest calculation does not include equity method accounting, fair value method accounting or the gain on the deconsolidation of subsidiary related to resTORbio or Akili, which is recorded within PureTech Health, LLC. Please refer to Note 5.</span></div><div style="margin-bottom:2pt"><span><br/></span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On July 19, 2019 PureTech and a third party investor converted their convertible debt in Follica to Follica Preferred shares (presented as liabilities) and Follica common shares. The amount of convertible debt converted by the third party investor into Follica common shares amounted to $2.4 million (see also Note 16). As a result of the conversion Follica NCI share (in Follica common stock) was reduced from 68 percent to 19.9 percent, which resulted in a reduction in the NCI share in Follica’s shareholders’ deficit of $19.9 million. The excess of the change in the book value of NCI ($19.9 million noted above) over the contribution made by NCI ($2.4 million) amounted to $17.5 million and was recorded as a loss directly in shareholders’ equity.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During 2019 a subsidiary of the Company fully funded by the Company ceased its operations and became inactive. This resulted in a change in the NCI share in the subsidiary deficit. As a result the Company recorded a loss directly in equity of $3.1 million.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On October 1, 2019, PureTech acquired the remaining 10.0 percent of minority non-controlling interests of PureTech LYT, Inc. (previously named Ariya Therapeutics, Inc.), increasing its ownership from 90.0 percent to 100.0 percent. In consideration for the acquisition of minority interests, PureTech issued 2,126,338 shares of common shares. The fair value of the shares issued in consideration for the minority non-controlling interest amounted to $9.1 million. The carrying amount of the non-controlling interest at the acquisition was a $24.0 million deficit and the excess of the consideration paid over the book value of the non-controlling interest of approximately $33.1 million was recorded directly in shareholders’ equity.</span></div> <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes the changes in the equity classified non-controlling ownership interest in subsidiaries by reportable segment:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:39.802%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.722%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Internal</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Controlled Founded Entities</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Non-Controlled Founded<br/>Entities</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Parent Company &amp; Other<br/>$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total<br/>$000s</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1, 2018</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,484)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(18,869)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(125,758)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">525 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(145,586)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of comprehensive loss</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(7,315)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10,710)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,980)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(27,005)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiary</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">55,168 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">55,168 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Equity settled share-based payments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,476 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,345 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">67 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,888 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at December 31, 2018 and January 1, 2019</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,799)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(27,103)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(73,225)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">592 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(108,535)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of comprehensive loss</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15,264)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15,862)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(23,953)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(55,079)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiary</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">97,178 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">97,178 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary note conversion and changes in NCI ownership interest</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">23,049 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">23,049 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Equity settled share-based payments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,683 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,683 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Purchase of minority interest</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">24,039 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">24,039 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">24 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">25 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at December 31, 2019 and January 1, 2020</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(18,233)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">593 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(17,640)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of comprehensive loss</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,402)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,417)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Equity settled share-based payments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,822 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,822 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">30 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">24 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2020</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(16,783)</span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">573</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(16,210)</span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> -1484000 -18869000 -125758000 525000 -145586000 -7315000 -10710000 -8980000 0 -27005000 0 0 55168000 0 55168000 0 2476000 6345000 67000 8888000 -8799000 -27103000 -73225000 592000 -108535000 -15264000 -15862000 -23953000 0 -55079000 0 0 97178000 0 97178000 0 23049000 0 0 23049000 0 1683000 0 0 1683000 24039000 0 0 0 24039000 24000 0 0 1000 25000 0 -18233000 0 593000 -17640000 0 -1402000 0 -15000 -1417000 0 2822000 0 0 2822000 0 30000 0 -6000 24000 0 -16783000 0 573000 -16210000 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following tables summarize the financial information related to the Group’s subsidiaries with material non-controlling interests, aggregated for interests in similar entities, and before and after intra group eliminations.</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:39.802%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.722%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the year ended December 31</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Internal<br/>$000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Controlled Founded Entities<br/>$000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Non-Controlled Founded<br/>Entities<br/>$000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Intra-group eliminations</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Total</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Statement of Comprehensive Loss</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total revenue</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,224</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,224</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) for the year</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(55,942)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,073</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(54,869)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other comprehensive income/(loss)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total comprehensive income/(loss) for the year</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(55,942)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,073</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(54,869)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Statement of Financial Position</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">68,346</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(7)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">68,339</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total liabilities</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">200,430</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(14,621)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">185,809</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Net assets/(liabilities)</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(132,084)</span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14,615</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(117,470)</span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of December 31, 2020, Controlled Founded Entities with non-controlling interests primarily include Alivio Therapeutics, Inc., Follica Incorporated, Sonde Health Inc., and Vedanta Biosciences, Inc. Ownership interests of the non-controlling interests in Alivio Therapeutics, Inc., Follica Incorporated, Sonde Health Inc., and Vedanta Biosciences, Inc are 8.1 percent, 19.9 percent, 4.5 percent and 0.4 percent, respectively. In addition, Non-controlling interests include the amounts recorded for subsidiary stock options, with the vast majority comprising of Vedanta stock options.</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the year ended December 31</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Internal<br/>$000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Controlled Founded Entities<br/> $000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Non-Controlled Founded<br/>Entities</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:4.55pt;font-weight:400;line-height:120%;position:relative;top:-2.44pt;vertical-align:baseline">1</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Statement of Comprehensive Loss</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,079 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,968 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) for the year</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(24,289)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(26,250)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(47,905)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other comprehensive income/(loss)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total comprehensive income/(loss) for the year</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(24,289)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(26,250)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(47,915)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Statement of Financial Position</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">17,614 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,290 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total liabilities</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,510 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">50,554 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net Liabilities</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,104 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(45,264)</span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Non-Controlled Founded Entities non-controlling interest calculation does not include equity method accounting, fair value method accounting or the gain on the deconsolidation of subsidiary related to Vor, Karuna, Gelesis, resTORbio or Akili, which is recorded within PureTech Health, LLC. Please refer to Note 5.</span></div><div style="margin-bottom:2pt"><span><br/></span></div><div style="margin-bottom:6pt;margin-top:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="9" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the year ended December 31</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Internal<br/>$000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Controlled Founded Entities<br/> $000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Non-Controlled Founded<br/>Entities</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:4.55pt;font-weight:400;line-height:120%;position:relative;top:-2.44pt;vertical-align:baseline">1</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Statement of Comprehensive Loss</span></td><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,195 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">18,504 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">20 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) for the year</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,454)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(26,206)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(41,239)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other comprehensive income/(loss)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(214)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(214)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total comprehensive income/(loss) for the year</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,454)</span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(26,420)</span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(41,453)</span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Non-Controlled Founded Entities non-controlling interest calculation does not include equity method accounting, fair value method accounting or the gain on the deconsolidation of subsidiary related to resTORbio or Akili, which is recorded within PureTech Health, LLC. Please refer to Note 5.</span></div> 0 5224000 0 5224000 0 -55942000 0 1073000 -54869000 0 0 0 0 0 -55942000 0 1073000 -54869000 0 68346000 0 -7000 68339000 0 200430000 0 -14621000 185809000 0 -132084000 0 14615000 -117470000 0.081 0.199 0.045 0.004 6079000 1968000 0 -24289000 -26250000 -47905000 0 0 -10000 -24289000 -26250000 -47915000 17614000 5290000 0 11510000 50554000 0 6104000 -45264000 0 2195000 18504000 20000 -8454000 -26206000 -41239000 0 -214000 -214000 -8454000 -26420000 -41453000 2400000 0.68 0.199 19900000 19900000 2400000 17500000 3100000 0.100 0.900 1.000 2126338 9100000 24000000.0 33100000 Trade and Other Payables <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Information regarding Trade and other payables was as follows: </span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></div></td><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade payables</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,871</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,098 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Accrued expenses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">9,090</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,651 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income tax payable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,260</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">93 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,606</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total trade and other payables</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">21,826</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19,842 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div> <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Information regarding Trade and other payables was as follows: </span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></div></td><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade payables</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,871</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,098 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Accrued expenses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">9,090</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,651 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income tax payable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,260</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">93 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,606</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total trade and other payables</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">21,826</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19,842 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div> 8871000 11098000 9090000 8651000 1260000 93000 2606000 0 21826000 19842000 Long-term loan<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In September 2020, Vedanta entered into a $15.0 million loan and security agreement with Oxford Finance LLC. The loan is secured by Vedanta's assets, including equipment, inventory and intellectual property. The loan bears a floating interest rate of 7.7 percent plus the greater of (i) 30 day U.S. Dollar LIBOR reported in the Wall Street Journal or (ii) 0.17 percent. The loan matures September 2025 and requires interest only payments for the initial 24 months. The loan also carries a Final fee upon full repayment of 7.0 percent of the original principal or $1.1 million. For loan consideration, Vedanta also issued Oxford Finance LLC 12,886 Series C-2 preferred share warrants with an exercise price of $23.28 per share, expiring September 2030. The outstanding loan balance totaled approximately $14.8 million as of December 31, 2020.</span></div><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes long-term loan obligations as at December 31, 2020 and 2019:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Long-term loan</span></td></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1,</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net loan proceeds</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14,720</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Accrued interest</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">496</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest paid</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(296)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassification of accrued interest to other current liabilities</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(102)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance at December 31,</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14,818</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes Vedanta's principal payments for the long-term loan as of December 31, 2020:</span></div><div style="margin-bottom:2pt"><span><br/></span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:27.982%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Balance Type</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2023</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2024</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2025</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Principal</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,491 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,721 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,112 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,676 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15,000 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Unamortized loan discount and issuance costs</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(182)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,491</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,721</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,112</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,676</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14,818</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> 15000000.0 0.077 0.0017 0.070 1100000 12886 23.28 14800000 <div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes long-term loan obligations as at December 31, 2020 and 2019:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Long-term loan</span></td></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1,</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net loan proceeds</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14,720</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Accrued interest</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">496</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest paid</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(296)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassification of accrued interest to other current liabilities</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(102)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance at December 31,</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14,818</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> 0 0 14720000 0 496000 0 -296000 0 -102000 0 14818000 0 <div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes Vedanta's principal payments for the long-term loan as of December 31, 2020:</span></div><div style="margin-bottom:2pt"><span><br/></span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:27.982%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Balance Type</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2023</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2024</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2025</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Principal</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,491 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,721 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,112 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,676 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15,000 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Unamortized loan discount and issuance costs</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(182)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,491</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,721</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,112</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,676</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14,818</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> 0 1491000 4721000 5112000 3676000 15000000 0 0 0 0 0 -182000 0 1491000 4721000 5112000 3676000 14818000 Leases <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The activity related to the Group’s right of use asset and lease liability for the year ended December 31, 2020 and 2019 is as follows:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Right of use asset, net</span></td></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1,</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">22,383</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,353 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19,434 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subleases</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,580)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,699)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,237)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Adjustments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">414</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidated</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,587)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance at December 31,</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">20,098</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22,383 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total lease liability</span></td></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1,</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">37,843</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,995 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">30,305 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash paid for rent (principal + interest)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(5,263)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,173)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest expense</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,354</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,495 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Adjustments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">414</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidated</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,779)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance at December 31,</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">35,348</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">37,843 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following details the short term and long-term portion of the lease liability as at December 31, 2020 and 2019:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:middle"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total lease liability</span></td></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term Portion of Lease Liability</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,261</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,929 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Long-term Portion of Lease Liability</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">32,088</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">34,914 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total Lease Liability</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">35,348</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">37,843 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table details the future maturities of the lease liability, showing the undiscounted lease payments to be paid after the reporting date:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:87.080%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.720%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Less than one year</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,422</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">One to two years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,609</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Two to three years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6,275</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Three to four years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6,489</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Four to five years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,101</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">More than five years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">16,452</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total undiscounted lease maturities</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">45,348</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">10,000</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total lease liability</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">35,348</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the year ended December 31, 2019, PureTech entered into a lease agreement for certain premises consisting of approximately 50,858 rentable square feet of space located at 6 Tide Street. The lease commenced on April 26, 2019 (“Commencement Date”) for an initial term consisting of ten years and three months and there is an option to extend for two consecutive periods of five years each. The Company assessed at lease commencement date whether it is reasonably certain to exercise the extension options and deemed such options not reasonably certain to be exercised. The Company will reassess whether it is reasonably certain to exercise the options only if there is a significant event or significant changes in circumstances within its control. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On June 26, 2019, PureTech executed a sublease agreement with Gelesis. The lease is for the approximately 9,446 rentable square feet located on the sixth floor of the Company’s former offices at the 501 Boylston Street building. The sublessee obtained possession of the premises on June 1, 2019 and the rent period term began on June 1, 2019 and expires on August 31, 2025. The sublease was determined to be a finance lease and the Group, therefore, derecognized the right of use asset and recognized a lease receivable at inception of the sublease. As of December 31, 2020 the balances related to the sublease were as follows:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.566%"><tr><td style="width:1.0%"/><td style="width:81.298%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.502%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:middle"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total lease receivable</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term Portion of Lease Receivable</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">381 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Long-term Portion of Lease Receivable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,700 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total Lease Receivable</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,082</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table details the future maturities of the lease receivable, showing the undiscounted lease payments to be received after the reporting date:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.566%"><tr><td style="width:1.0%"/><td style="width:81.298%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.502%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Less than one year</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">494</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">One to two years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">504</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Two to three years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">513</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Three to four years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">523</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Four to five years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">353</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">More than five years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total undiscounted lease receivable</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,387</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Unearned Finance income</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">305</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Net investment in the lease</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,082</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On August 6, 2019, PureTech executed a sublease agreement with Dewpoint Therapeutics, Inc. (“Dewpoint”). The sublease is for approximately 11,852 rentable square feet located on the third floor of the 6 Tide Street building, where the Company’s offices are currently located. Dewpoint obtained possession of the premises on September 1, 2019 with a rent period term that began on September 1, 2019 and expires on August 31, 2021. The sublease was determined to be an operating lease. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Rental income recognized by the Company during the year ended December 31, 2020 was $1.08 million and is included in the Other income/(expense) line item in the Consolidated Statements of Comprehensive Income/(Loss). The following table details the future payments under the sublease, showing the undiscounted lease payments to be received after the reporting date:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.566%"><tr><td style="width:1.0%"/><td style="width:81.298%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.502%"/><td style="width:0.1%"/></tr><tr style="height:11pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td></tr><tr style="height:11pt"><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Less than one year</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">722</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">722</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total rent expense under the Group's operating leases was approximately $2.5 million during the year ended December 31, 2018. Rent expense is included in the General and administrative expenses line item in the Consolidated Statements of Comprehensive Income/(Loss).</span></div> <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The activity related to the Group’s right of use asset and lease liability for the year ended December 31, 2020 and 2019 is as follows:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Right of use asset, net</span></td></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1,</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">22,383</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,353 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19,434 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subleases</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,580)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,699)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,237)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Adjustments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">414</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidated</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,587)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance at December 31,</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">20,098</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22,383 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> 22383000 10353000 10353000 0 19434000 0 -2580000 -2699000 -3237000 414000 0 0 -1587000 20098000 22383000 <table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total lease liability</span></td></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1,</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">37,843</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,995 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">30,305 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash paid for rent (principal + interest)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(5,263)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,173)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest expense</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,354</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,495 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Adjustments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">414</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidated</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,779)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance at December 31,</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">35,348</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">37,843 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table> 37843000 10995000 0 30305000 -5263000 -4173000 2354000 2495000 414000 0 0 -1779000 35348000 37843000 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following details the short term and long-term portion of the lease liability as at December 31, 2020 and 2019:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:middle"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total lease liability</span></td></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term Portion of Lease Liability</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,261</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,929 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Long-term Portion of Lease Liability</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">32,088</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">34,914 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total Lease Liability</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">35,348</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">37,843 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> 3261000 2929000 32088000 34914000 35348000 37843000 The following table details the future maturities of the lease liability, showing the undiscounted lease payments to be paid after the reporting date:<table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:87.080%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.720%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Less than one year</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,422</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">One to two years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,609</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Two to three years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6,275</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Three to four years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6,489</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Four to five years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,101</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">More than five years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">16,452</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total undiscounted lease maturities</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">45,348</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">10,000</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total lease liability</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">35,348</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table> 5422000 5609000 6275000 6489000 5101000 16452000 45348000 10000000 35348000 As of December 31, 2020 the balances related to the sublease were as follows:<table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.566%"><tr><td style="width:1.0%"/><td style="width:81.298%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.502%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:middle"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total lease receivable</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term Portion of Lease Receivable</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">381 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Long-term Portion of Lease Receivable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,700 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total Lease Receivable</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,082</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table> 381000 1700000 2082000 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table details the future maturities of the lease receivable, showing the undiscounted lease payments to be received after the reporting date:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.566%"><tr><td style="width:1.0%"/><td style="width:81.298%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.502%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Less than one year</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">494</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">One to two years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">504</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Two to three years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">513</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Three to four years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">523</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Four to five years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">353</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">More than five years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total undiscounted lease receivable</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,387</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Unearned Finance income</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">305</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Net investment in the lease</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,082</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> 494000 504000 513000 523000 353000 0 2387000 305000 2082000 1080000.00 The following table details the future payments under the sublease, showing the undiscounted lease payments to be received after the reporting date:<table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.566%"><tr><td style="width:1.0%"/><td style="width:81.298%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.502%"/><td style="width:0.1%"/></tr><tr style="height:11pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td></tr><tr style="height:11pt"><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Less than one year</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">722</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">722</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table> 722000 722000 2500000 Capital and Financial Risk Management Capital Risk Management<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group's capital and financial risk management policy is to maintain a strong capital base so as to support its strategic priorities, maintain investor, creditor and market confidence as well as sustain the future development of the business. The Group’s objectives when managing capital are to safeguard its ability to continue as a going concern in order to provide returns for shareholders and benefits for other stakeholders and to maintain an optimal capital structure to reduce the cost of capital. To maintain or adjust the capital structure, the Group may issue new shares or incur new debt. The Group has some external debt and no material externally imposed capital requirements. The Group’s share capital is clearly set out in Note 14.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Management continuously monitors the level of capital deployed and available for deployment in the Internal and Parent segments as well as at Founded Entities. The Directors seek to maintain a balance between the higher returns that might be possible with higher levels of deployed capital and the advantages and security afforded by a sound capital position.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s Directors have overall responsibility for establishment and oversight of the Group's capital and risk management framework. The Group is exposed to certain risks through its normal course of operations. The Group’s main objective in using financial instruments is to promote the development and commercialization of intellectual property through the raising and investing of funds for this purpose. The Group’s policies in calculating the nature, amount and timing of investments are determined by planned future investment activity. Due to the nature of activities and with the aim to maintain the investors’ funds as secure and protected, the Group’s policy is to hold any excess funds in highly liquid and readily available financial instruments and maintain insignificant exposure to other financial risks.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">COVID-19</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In December 2019, illnesses associated with COVID-19 were reported and the virus has since caused widespread and significant disruption to daily life and economies across geographies. The World Health Organization has classified the outbreak as a pandemic. The Group's operations, financial condition and results have not been significantly impacted during the year ended December 31, 2020 as a result of the COVID-19 pandemic. In response to the COVID-19 pandemic, the Group has taken swift action to ensure the safety of employees and other stakeholders. The Group continues to monitor the latest developments regarding the COVID-19 pandemic on business, operations, and financial condition and results, and have made certain assumptions regarding the pandemic for purposes of the Group's operational planning and financial projections, including assumptions regarding the duration and severity of the pandemic and the global macroeconomic impact of the pandemic. Despite careful tracking and planning, however, the Group is unable to accurately predict the extent of the impact of the pandemic on the business, operations, and financial condition and results in future periods due to the uncertainty of future developments. The Group is focused on all aspects of the business and is implementing measures aimed at mitigating issues where possible including by using digital technology to assist operations for R&amp;D and enabling functions.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Credit Risk</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group has exposure to the following risks arising from financial instruments:</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Credit risk is the risk of financial loss to the Group if a customer or counterparty to a financial instrument fails to meet its contractual obligations. Financial instruments that potentially subject the Group to concentrations of credit risk consist principally of cash and cash equivalents, investments held at fair value and trade and other receivables. The Group held the following balances:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash and cash equivalents</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">403,881</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">132,360 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term investments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">30,088 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other receivables</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,558</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,977 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">406,438</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">164,425 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group invests its excess cash in U.S. Treasury Bills, U.S. debt obligations and money market accounts, which the Group believes are of high credit quality. Further the Group's cash, cash equivalents and short-term investments are held at diverse, investment-grade financial institutions.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group assesses the credit quality of customers on an ongoing basis. The credit quality of financial assets that are neither past due nor impaired is assessed by historical and recent payment history, counterparty financial position, reference to credit ratings (if available) or to historical information about counterparty default rates. The Group does not have expected credit losses owing largely to a small number of counterparties and the high credit quality of such counterparties.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The aging of trade and other receivables that were not impaired at December 31 is as follows:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/></tr><tr style="height:11pt"><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #dbdbdb;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Neither past due or impaired</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,558</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,977 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #dbdbdb;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,558</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,977 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Liquidity Risk</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Liquidity risk is the risk that the Group will encounter difficulty in meeting the obligations associated with its financial liabilities that are settled by delivering cash or another financial asset. The Group actively manages its risk of a funds shortage by closely monitoring the maturity of its financial assets and liabilities and projected cash flows from operations, under both normal and stressed conditions, without incurring unacceptable losses or risking damage to the Group’s reputation. Due to the nature of these financial liabilities, the funds are available on demand to provide optimal financial flexibility.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The table below summarizes the maturity profile of the Group’s financial liabilities, including subsidiary preferred shares that have customary liquidation preferences, as of December 31, 2020 and 2019 based on contractual undiscounted payments:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:39.802%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.722%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></td></tr><tr style="height:26pt"><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Carrying Amount<br/>$000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Within Three Months<br/>$000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Three to Twelve Months<br/>$000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">One to Five Years<br/>$000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Total<br/>$000s</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Long-term loan</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14,818</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">296</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">905</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">18,780</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">19,981</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary notes payable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">26,455</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,455</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">25,000</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">26,455</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other payables</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">21,826</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">21,826</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">21,826</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Warrants</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,206</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,206</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,206</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary preferred shares (Note 15)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">118,972</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">118,972</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">118,972</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">190,278</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">150,756</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">25,905</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">18,780</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">195,441</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:39.802%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.722%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></td></tr><tr style="height:26pt"><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Carrying Amount<br/>$000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Within Three Months<br/>$000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Three to Twelve Months<br/>$000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">One to Five Years<br/>$000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total<br/>$000s</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary notes payable</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,455 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,455 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,455 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other payables</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19,842 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19,842 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19,842 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Warrants</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,997 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,997 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,997 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary preferred shares (Note 15)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100,989 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100,989 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100,989 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">130,283 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">130,283 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">130,283 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Redeemable only upon a liquidation or Deemed liquidation event, as defined in the applicable shareholder documents.</span></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Warrants issued by subsidiaries to third parties to purchase preferred shares.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest Rate Sensitivity </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of December 31, 2020, the Group had cash and cash equivalents of $403.9 million. The Group's exposure to interest rate sensitivity is impacted by changes in the underlying U.K. and U.S. bank interest rates. The Group has not entered into investments for trading or speculative purposes. Due to the conservative nature of the Group's investment portfolio, which is predicated on capital preservation and investments in short duration, high-quality U.S. Treasury Bills and U.S. debt obligations and related money market accounts, a change in interest rates would not have a material effect on the fair market value of the Group's portfolio, and therefore the Group does not expect operating results or cash flows to be significantly affected by changes in market interest rates.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Controlled Founded Entity Investments</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group maintains investments in certain Controlled Founded Entities. The Group’s investments in Controlled Founded Entities are eliminated as intercompany transactions upon financial consolidation. The Group is however exposed to a preferred share liability owing to the terms of existing preferred shares and the ownership of Controlled Founded Entities preferred shares by third parties. As discussed in Note 15, certain of the Group’s subsidiaries have issued preferred shares that include the right to receive a payment in the event of any voluntary or involuntary liquidation, dissolution or winding up of a subsidiary, which shall be paid out of the assets of the subsidiary available for distribution to shareholders and before any payment shall be made to holders of ordinary shares. The liability of preferred shares is maintained at fair value through the profit and loss. The Group’s strong cash position, budgeting and forecasting processes, as well as decision making and risk mitigation framework enable the Group to robustly monitor and support the business activities of the Controlled Founded Entities to ensure no exposure to credit losses and ultimately dissolution or liquidation. Accordingly, the Group views exposure to 3rd party preferred share liability as low. Please refer to Notes 15 and 16 for further information regarding the Group's exposure to Controlled Founded Entity Investments. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-Controlled Founded Entity Investments</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group maintains certain investments in Non-Controlled Founded Entities which are deemed either as investments and accounted for as investments held at fair value or associates and accounted for under the equity method (please refer to Note 1). The Group's exposure to investments held at fair value is $530.2 million as of December 31, 2020 and the Group may or may not be able to realize the value in the future. Accordingly, the Group views the risk as high. The Group’s exposure to investments in associates is limited to the carrying amount of the investment in an Associate. The Group is not exposed to further contractual obligations or contingent liabilities beyond the value of initial investment. As of December 31, 2020, Gelesis was the only associate. The carrying amount of the investment in Gelesis as an associate was zero. Accordingly, the Group does not view this as a risk. Please refer to Notes 5,6 and 16 for further information regarding the Group's exposure to Non-Controlled Founded Entity Investments. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Equity Price Risk </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of December 31, 2020, the Group held 3,406,564 common shares of Karuna. The fair value of the Group's investment in the common stock of Karuna was $346.1 million .</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The investment in Karuna is exposed to fluctuations in the market price of these common shares. The effect of a 10.0 percent adverse change in the market price of Karuna common shares as of December 31, 2020 would have been a loss of approximately $34.6 million recognized as a component of Other income (expense) in the Consolidated Statements of Comprehensive Income/(Loss). </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Foreign Exchange Risk</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group maintains consolidated financial statements in the Group's functional currency, which is the U.S. dollar. Monetary assets and liabilities denominated in currencies other than the functional currency are translated into the functional currency at rates of exchange prevailing at the balance sheet dates. Non-monetary assets and liabilities denominated in foreign currencies are translated into the functional currency at the exchange rates prevailing at the date of the transaction. Exchange gains or losses </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">arising from foreign currency transactions are included in the determination of net income (loss) for the respective periods. Such foreign currency gains or losses were not material for all reported periods. See Note 9.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group recorded foreign currency losses in respect of foreign operations of $0.5 million, $0.0 million and $0.2 million for the periods ended December 31, 2020, December 31, 2019, and December 31, 2018, respectively, which are included within Other comprehensive income/(loss) in the Consolidated Statements of Comprehensive Income/(Loss). </span></div>The Group does not currently engage in currency hedging activities since its foreign currency risk is limited, but the Group may begin to do so in the future if and when its foreign currency risk exposure changes. Instruments that may be used to hedge future risks include foreign currency forward and swap contracts. These instruments may be used to selectively manage risks, but there can be no assurance that the Group will be fully protected against material foreign currency fluctuations. Financial instruments that potentially subject the Group to concentrations of credit risk consist principally of cash and cash equivalents, investments held at fair value and trade and other receivables. The Group held the following balances:<table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash and cash equivalents</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">403,881</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">132,360 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term investments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">30,088 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other receivables</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,558</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,977 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">406,438</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">164,425 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table> 403881000 132360000 0 30088000 2558000 1977000 406438000 164425000 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The aging of trade and other receivables that were not impaired at December 31 is as follows:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/></tr><tr style="height:11pt"><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:1pt solid #dbdbdb;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Neither past due or impaired</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,558</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,977 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #dbdbdb;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,558</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,977 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div> 2558000 1977000 2558000 1977000 The table below summarizes the maturity profile of the Group’s financial liabilities, including subsidiary preferred shares that have customary liquidation preferences, as of December 31, 2020 and 2019 based on contractual undiscounted payments:<div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:39.802%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.722%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></td></tr><tr style="height:26pt"><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Carrying Amount<br/>$000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Within Three Months<br/>$000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Three to Twelve Months<br/>$000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">One to Five Years<br/>$000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Total<br/>$000s</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Long-term loan</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14,818</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">296</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">905</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">18,780</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">19,981</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary notes payable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">26,455</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,455</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">25,000</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">26,455</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other payables</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">21,826</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">21,826</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">21,826</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Warrants</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,206</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,206</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,206</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary preferred shares (Note 15)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">118,972</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">118,972</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">118,972</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">190,278</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">150,756</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">25,905</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">18,780</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">195,441</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:39.802%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.722%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></td></tr><tr style="height:26pt"><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Carrying Amount<br/>$000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Within Three Months<br/>$000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Three to Twelve Months<br/>$000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">One to Five Years<br/>$000s</span></div></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total<br/>$000s</span></div></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary notes payable</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,455 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,455 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,455 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other payables</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19,842 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19,842 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19,842 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Warrants</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,997 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,997 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,997 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary preferred shares (Note 15)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100,989 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100,989 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100,989 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">130,283 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">130,283 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">130,283 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Redeemable only upon a liquidation or Deemed liquidation event, as defined in the applicable shareholder documents.</span></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Warrants issued by subsidiaries to third parties to purchase preferred shares.</span></div> 14818000 296000 905000 18780000 19981000 26455000 1455000 25000000 0 26455000 21826000 21826000 0 0 21826000 8206000 8206000 0 0 8206000 118972000 118972000 0 0 118972000 190278000 150756000 25905000 18780000 195441000 1455000 1455000 0 0 1455000 19842000 19842000 0 0 19842000 7997000 7997000 0 0 7997000 100989000 100989000 0 0 100989000 130283000 130283000 0 0 130283000 403900000 530200000 0 3406564 346100000 0.100 34600000 500000 -0.0 -200000 Commitments and Contingencies <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group is party to certain licensing agreements where the Company is licensing IP from third parties. In consideration for such licenses the Group has made upfront payments and may be required to make additional contingent payments based on developmental and sales milestones and/or royalty on future sales. As of December 31, 2020 these milestone events have not yet occurred and therefore the Company does not have a present obligation to make the related payments in respect of the licenses. Many of these milestone events are remote of occurring. As of December 31, 2020 payments in respect of developmental milestones that are dependent on events that are outside the control of the company but are reasonably possible to occur amounted to approximately $5.3 million. These milestone amounts represent an aggregate of multiple milestone payments depending on different milestone events in multiple agreements. The probability that all such milestone events will occur in the aggregate is remote. Payments made to license IP represent the acquisition cost of intangible assets. See Note 12.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company is party to certain sponsored research arrangements as well as arrangements with contract manufacturing and contract research organizations, whereby the counterparty provides the Company with research and/or manufacturing services. As of December 31, 2020 the noncancellable commitments in respect of such contracts amounted to approximately $5.1 million.</span></div> 5300000 5100000 Related Parties Transactions <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Related Party Subleases</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During 2019, PureTech executed sublease agreements with a related party Gelesis. Please refer to Note 21 for further details regarding the sublease.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Key Management Personnel Compensation</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Key management includes executive directors and members of the executive management team of the Group. The key management personnel compensation of the Group was as follows for the years ended December 31:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term employee benefits</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,833</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,543 </span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,998 </span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,822</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,774 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,062 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">10,656</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,317 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,060 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="background-color:#ffffff;color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term employee benefits include salaries, health care and other non-cash benefits. Share-based payments are generally subject to vesting terms over future periods.</span></div><div><span style="background-color:#ffffff;color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Convertible Notes Issued to Directors</span></div><div style="margin-bottom:5pt"><span style="background-color:#ffffff;color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Certain members of the Group have invested in convertible notes issued by the Group’s subsidiaries. As of December 31, 2020, 2019 and 2018, the outstanding related party notes payable totaled $89 thousand, $84 thousand and $79 thousand, respectively, including principal and interest. </span></div><div style="margin-bottom:5pt"><span style="background-color:#ffffff;color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The notes issued to related parties bear interest rates, maturity dates, discounts and other contractual terms that are the same as those issued to outside investors during the same issuances, as described in Note 17.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Directors’ and Senior Managers’ Shareholdings and Share Incentive Awards</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Directors and senior managers hold beneficial interests in shares in the following businesses and sourcing companies as at December 31, 2020:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.566%"><tr><td style="width:1.0%"/><td style="width:28.962%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:33.323%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.738%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.738%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.739%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Business Name (Share Class)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Number of shares held as of December 31, 2020</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Number of options held as of December 31, 2020</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Ownership<br/>Interest¹</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Directors:</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #183964;padding:0 1pt"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Ms Daphne Zohar²</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis (Common)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">59,443</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,339,114</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5.10</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Dame Marjorie Scardino</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Kiran Mazumdar-Shaw</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Dr Robert Langer</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega (Common)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">332,500</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4.24</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Alivio (Common)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,575,000</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6.14</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Dr Raju Kucherlapati</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Enlight (Class B Common)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">30,000</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3.00</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis (Common)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">20,000</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.10</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr></table></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.566%"><tr><td style="width:1.0%"/><td style="width:28.962%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:33.323%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.738%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.738%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.739%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Dr John LaMattina</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">4</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Akili (Series A-2 Preferred)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">37,372</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.15</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Akili (Series C Preferred)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,755</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.05</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis (Common)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">4</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">51,070</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.20</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis (Common)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">5</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">83,050</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.30</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis (Series A-1 Preferred)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">4</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">49,253</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.20</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta Biosciences (Common)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">25,000</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.22</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Mr Christopher Viehbacher</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Mr Stephen Muniz</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis (Common)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">5</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">20,000</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.10</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Senior Managers:</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Dr Bharatt Chowrira</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Karuna (Common)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">5</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">10,000</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.04</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Dr Eric Elenko</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Dr Joep Muijrers</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Dr. George Farmer</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Dr Joseph Bolen</span></td><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vor (Common)</span></td><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">125,000</span></td><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.04</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Ownership interests as of December 31, 2020 are calculated on a diluted basis, including issued and outstanding shares, warrants and options (and written commitments to issue options) but excluding unallocated shares authorized to be issued pursuant to equity incentive plans and any shares issuable upon conversion of outstanding convertible promissory notes.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Common shares and options held by Yishai Zohar, who is the husband of Ms. Zohar. Ms. Zohar does not have any direct interest in the share capital of Gelesis. Ms Zohar recuses herself from any and all material decisions with regard to Gelesis.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">3    Shares held through Dr Bennett Shapiro and Ms Fredericka F. Shapiro, Joint Tenants with Right of Survivorship.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">4    Dr John and Ms Mary LaMattina hold 50,540 shares of common shares and 49,524 shares of Series A-1 preferred shares in Gelesis. Individually, Dr LaMattina holds 530 shares of Gelesis and convertible notes issued by Appeering in the aggregate principal amount of $50,000.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">5    Options to purchase the listed shares were granted in connection with the service on such founded entity’s Board of Directors and any value realized therefrom shall be assigned to PureTech Health, LLC. </span></div>Directors and senior managers hold 23,245,840 ordinary shares and 8.1 percent voting rights of the Company as of December 31, 2020. This amount excludes options to purchase 3,459,344 ordinary shares. This amount also excludes 6,204,268 shares, which are issuable based on the terms of performance based RSU awards granted to certain senior managers covering the financial years 2020, 2019 and 2018. Such shares will be issued to such senior managers in future periods provided that performance conditions are met and certain of the shares will be withheld for payment of customary withholding taxes. <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Key management includes executive directors and members of the executive management team of the Group. The key management personnel compensation of the Group was as follows for the years ended December 31:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term employee benefits</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,833</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,543 </span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,998 </span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,822</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,774 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,062 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">10,656</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,317 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,060 </span></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="background-color:#ffffff;color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term employee benefits include salaries, health care and other non-cash benefits. Share-based payments are generally subject to vesting terms over future periods.</span></div> 4833000 5543000 3998000 5822000 2774000 3062000 10656000 8317000 7060000 89000 84000 79000 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Directors and senior managers hold beneficial interests in shares in the following businesses and sourcing companies as at December 31, 2020:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.566%"><tr><td style="width:1.0%"/><td style="width:28.962%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:33.323%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.738%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.738%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.739%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Business Name (Share Class)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Number of shares held as of December 31, 2020</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Number of options held as of December 31, 2020</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Ownership<br/>Interest¹</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Directors:</span></td><td colspan="3" style="border-top:1pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:1pt solid #183964;padding:0 1pt"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Ms Daphne Zohar²</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis (Common)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">59,443</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,339,114</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5.10</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Dame Marjorie Scardino</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Kiran Mazumdar-Shaw</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Dr Robert Langer</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega (Common)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">332,500</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4.24</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Alivio (Common)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,575,000</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6.14</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Dr Raju Kucherlapati</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Enlight (Class B Common)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">30,000</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3.00</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis (Common)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">20,000</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.10</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr></table></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.566%"><tr><td style="width:1.0%"/><td style="width:28.962%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:33.323%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.738%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.738%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.739%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Dr John LaMattina</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">4</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Akili (Series A-2 Preferred)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">37,372</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.15</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Akili (Series C Preferred)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,755</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.05</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis (Common)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">4</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">51,070</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.20</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis (Common)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">5</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">83,050</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.30</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis (Series A-1 Preferred)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">4</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">49,253</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.20</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta Biosciences (Common)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">25,000</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.22</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Mr Christopher Viehbacher</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Mr Stephen Muniz</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis (Common)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">5</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">20,000</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.10</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Senior Managers:</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Dr Bharatt Chowrira</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Karuna (Common)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">5</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">10,000</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.04</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Dr Eric Elenko</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Dr Joep Muijrers</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Dr. George Farmer</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Dr Joseph Bolen</span></td><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vor (Common)</span></td><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="border-bottom:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">125,000</span></td><td colspan="2" style="border-bottom:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.04</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Ownership interests as of December 31, 2020 are calculated on a diluted basis, including issued and outstanding shares, warrants and options (and written commitments to issue options) but excluding unallocated shares authorized to be issued pursuant to equity incentive plans and any shares issuable upon conversion of outstanding convertible promissory notes.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Common shares and options held by Yishai Zohar, who is the husband of Ms. Zohar. Ms. Zohar does not have any direct interest in the share capital of Gelesis. Ms Zohar recuses herself from any and all material decisions with regard to Gelesis.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">3    Shares held through Dr Bennett Shapiro and Ms Fredericka F. Shapiro, Joint Tenants with Right of Survivorship.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">4    Dr John and Ms Mary LaMattina hold 50,540 shares of common shares and 49,524 shares of Series A-1 preferred shares in Gelesis. Individually, Dr LaMattina holds 530 shares of Gelesis and convertible notes issued by Appeering in the aggregate principal amount of $50,000.</span></div>5    Options to purchase the listed shares were granted in connection with the service on such founded entity’s Board of Directors and any value realized therefrom shall be assigned to PureTech Health, LLC. 59443 1339114 0.0510 0 0 0 0 0 0 0 332500 0.0424 0 1575000 0.0614 0 30000 0.0300 0 20000 0.0010 37372 0 0.0015 11755 0 0.0005 51070 0 0.0020 0 83050 0.0030 49253 0 0.0020 0 25000 0.0022 0 0 0 0 20000 0.0010 10000 0 0.0004 0 0 0 0 0 0 0 0 0 0 125000 0.0004 50540 49524 530 50000 23245840 0.081 3459344 6204268 Taxation <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax on the profit or loss for the year comprises current and deferred income tax. Tax is recognized in the Consolidated Statements of Comprehensive Income/(Loss) except to the extent that it relates to items recognized directly in equity.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For the years ended December 31, 2020, 2019 and 2018, the Group filed a consolidated U.S. federal income tax return which included all subsidiaries in which the Company owned greater than 80 percent of the vote and value. For the years ended December 31, 2020, 2019 and 2018, the Group filed certain consolidated state income tax returns which included all subsidiaries in which the Company owned greater than 50 percent of the vote and value. The remaining subsidiaries file separate U.S. tax returns.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Current income tax is the expected tax payable or receivable on the taxable income or loss for the year, using tax rates enacted or substantially enacted at the reporting date, and any adjustment to tax payable in respect of previous years.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax is recognized due to temporary differences between the carrying amounts of assets and liabilities for financial reporting purposes and the amounts used for taxation purposes. Deferred tax assets are recognized for unused tax losses, unused tax credits and deductible temporary differences to the extent that it is probable that future taxable profits will be available against which they can be used. Deferred tax assets are reviewed at each reporting date and are reduced to the extent that it is no longer probable that the related tax benefit will be realized.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax is measured at the tax rates that are expected to be applied to temporary differences when they reverse, using tax rates enacted or substantively enacted at the reporting date.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred income tax assets and liabilities are offset when there is a legally enforceable right to offset current tax assets against current tax liabilities and when the deferred income tax assets and liabilities relate to income taxes levied by the same taxation authority on either the same taxable entity or different taxable entities where there is an intention to settle the balances on a net basis.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred taxes are recognized in Consolidated Statements of Comprehensive Income/(Loss) except to the extent that they relate to items recognized directly in equity or in other comprehensive income.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amounts recognized in Consolidated Statements of Comprehensive Income/(Loss):</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) for the year</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,568</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">366,065 </span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(70,659)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income tax expense/(benefit)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14,401</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">112,409 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,221 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Income/(loss) before taxes</span></td><td colspan="2" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">18,969</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">478,474 </span></td><td style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(68,438)</span></td><td style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Recognized income tax expense/(benefit):</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Federal</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">21,796</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2 </span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Foreign</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">State</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">496 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total current income tax expense/(benefit)</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">21,796</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">498 </span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Federal</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(7,349)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">83,776 </span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,034 </span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Foreign</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(311)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">State</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(46)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28,633 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total deferred income tax expense/(benefit)</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(7,395)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">112,409 </span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,723 </span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total income tax expense/(benefit), recognized</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14,401</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">112,409 </span></td><td style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,221 </span></td><td style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The tax expense was $14.4 million, $112.4 million and $2.2 million in 2020, 2019 and 2018 respectively. The decrease in tax expense is primarily the result of the decrease in profit before tax.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reconciliation of Effective Tax Rate</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group is primarily subject to taxation in the U.S. A reconciliation of the U.S. federal statutory tax rate to the effective tax rate is as follows:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:26.738%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">%</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">%</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Weighted-average statutory rate</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,984</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">21.00</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">97,183 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">21.00 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(14,372)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">21.00 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Effects of state tax rate in U.S.</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,844</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">9.72</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22,111 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4.78 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,267)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4.77 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">R&amp;D and orphan drug tax credits</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(5,642)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(29.74)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,321)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1.37)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,268)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4.78 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payment measurement</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">327</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.73</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">433 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.09 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,429 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5.01)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Mark-to-market adjustments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">919</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4.84</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,725 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.80 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,745)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5.47 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Transaction Costs</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">361</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.91</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.00 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.00 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest Expense</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,258)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(11.91)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,030 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.22 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.00 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Executive Compensation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">827</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4.36</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.00 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.00 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Accretion on preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.00</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.00 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(0.03)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation adjustments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.00</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(13,658)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2.95)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,688 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(14.16)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Mark-to-market investment in subsidiary</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.00</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.00 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(55)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.08 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income of partnerships not subject to tax</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.00</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.00 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(78)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.11 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Recognition of deferred tax assets not previously recognized</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.00</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,251)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1.35)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.00 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Current year losses for which no deferred tax asset is recognized</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">13,948</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">73.53</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,514 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.14 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,012 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(19.01)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">91</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.48</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(356)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(0.06)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">854 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1.25)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14,401</span></td><td colspan="2" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">75.92</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">112,409</span></td><td colspan="2" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">24.29 </span></td><td style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,221</span></td><td colspan="2" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3.25)</span></td><td style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company is also subject to taxation in the UK but to date no taxable income has been generated in the UK. Changes in corporate tax rates can change both the current tax expense (benefit) as well as the deferred tax expense (benefit). </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred Tax Assets and Liabilities </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets have been recognized in the U.S. jurisdiction in respect of the following items:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Operating tax losses</span></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">39,901</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">68,690 </span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Capital loss carryovers</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,292 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research credits</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">10,805</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,931 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payments</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,429</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,711 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">358</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,125 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Lease Liability</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">9,657</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,339 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other temporary differences</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,078</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,117 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets</span></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">68,228</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="background-color:#ffffff;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">104,205 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investment in subsidiaries</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(120,676)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(173,069)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">ROU asset</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(5,491)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,115)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fixed assets</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(3,588)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,225)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other temporary differences</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(27)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax liabilities</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(129,782)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(182,409)</span></td><td style="background-color:#ffffff;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets (liabilities), net</span></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(61,554)</span></td><td style="background-color:#ffffff;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(78,204)</span></td><td style="background-color:#ffffff;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax liabilities, net, recognized</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">108,626</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">115,445 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets, net, recognized</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(142)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets (liabilities), net, not recognized</span></td><td colspan="2" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47,072</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">37,099 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">We have recognized deferred tax assets related to entities in the U.S. Federal and Massachusetts consolidated return groups due to future reversals of existing taxable temporary differences that will be sufficient to recover the net deferred tax assets. Our remaining deferred tax assets have not been recognized because it is not probable that future taxable profits will be available to support their realizability. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">There was movement in deferred tax recognized, which impacted income tax expense by approximately $7.4 million benefit, primarily related to changes in the value of investments. The Company sold a portion of its stock in Karuna during 2020 and was able to partially offset its gains by using various attributes (i.e. net operating losses, research and development credits, etc.) resulting in current tax expense of $21.8 million.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company had U.S. federal net operating losses carry forwards (“NOLs”) of approximately $169.7 million, $243.0 million and $238.1 million as of December 31, 2020, 2019 and 2018, respectively, which are available to offset future taxable income. These NOLs expire through 2037 with the exception of $101.9 million which is not subject to expiration. The Company had U.S. Federal research and development tax credits of approximately $3.9 million, $7.4 million and $6.7 million as of December 31, 2020, 2019 and 2018, respectively, which are available to offset future taxes that expire at various dates through 2040. The Company also had Federal Orphan Drug credits of approximately $5.2 million and $3.7 million as of December 31, 2020 and 2019, which are available to offset future taxes that expire at various dates through 2040. A portion of these Federal NOLs and credits can only be used to offset the profits from the Company’s subsidiaries who file separate Federal tax returns. These NOLs and credits are subject to review and possible adjustment by the Internal Revenue Service.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company had Massachusetts net operating losses carry forwards (“NOLs”) of approximately $67.4 million, $273.0 million and $179.5 million for the years ended December 31, 2020, 2019 and 2018, respectively, which are available to offset future taxable income. These NOLs expire at various dates beginning in 2030. The Company had Massachusetts research and development tax credits of approximately $2.1 million, $1.6 million and $1.3 million for the years ended December 31, 2020, 2019 and 2018, respectively, which are available to offset future taxes and expire at various dates through 2035. These NOLs and credits are subject to review and possible adjustment by the Massachusetts Department of Revenue. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Utilization of the NOLs and research and development credit carryforwards may be subject to a substantial annual limitation under Section 382 of the Internal Revenue Code of 1986 due to ownership change limitations that have occurred previously or that could occur in the future. These ownership changes may limit the amount of NOL and research and development credit carryforwards that can be utilized annually to offset future taxable income and tax, respectively. The Company notes that a 382 analysis was performed through December 31, 2020. The results of this analysis concluded that certain net operating losses were subject to limitation under Section 382 of the Internal Revenue Code. None of the Company’s tax attributes which are subject to a restrictive Section 382 limitation have been recognized in the financial statements. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Uncertain Tax Positions</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company has no uncertain tax positions as of December 31, 2020. U.S. corporations are routinely subject to audit by federal and state tax authorities in the normal course of business.</span></div> <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amounts recognized in Consolidated Statements of Comprehensive Income/(Loss):</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) for the year</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,568</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">366,065 </span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(70,659)</span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income tax expense/(benefit)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14,401</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">112,409 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,221 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Income/(loss) before taxes</span></td><td colspan="2" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">18,969</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">478,474 </span></td><td style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(68,438)</span></td><td style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div> 4568000 366065000 -70659000 14401000 112409000 2221000 18969000 478474000 -68438000 Recognized income tax expense/(benefit):<div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Federal</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">21,796</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2 </span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Foreign</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">State</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">496 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total current income tax expense/(benefit)</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">21,796</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">498 </span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Federal</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(7,349)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">83,776 </span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,034 </span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Foreign</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(311)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">State</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(46)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28,633 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total deferred income tax expense/(benefit)</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(7,395)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">112,409 </span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,723 </span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total income tax expense/(benefit), recognized</span></td><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14,401</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">112,409 </span></td><td style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,221 </span></td><td style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The tax expense was $14.4 million, $112.4 million and $2.2 million in 2020, 2019 and 2018 respectively. The decrease in tax expense is primarily the result of the decrease in profit before tax.</span></div> 21796000 0 2000 0 0 0 0 0 496000 21796000 0 498000 -7349000 83776000 2034000 0 0 -311000 -46000 28633000 0 -7395000 112409000 1723000 14401000 112409000 2221000 14400000 112400000 2200000 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group is primarily subject to taxation in the U.S. A reconciliation of the U.S. federal statutory tax rate to the effective tax rate is as follows:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:26.738%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2018</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">%</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">%</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></td><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Weighted-average statutory rate</span></td><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,984</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">21.00</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">97,183 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">21.00 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:1pt solid #000;padding:0 1pt"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(14,372)</span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">21.00 </span></td><td style="border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Effects of state tax rate in U.S.</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,844</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">9.72</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22,111 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4.78 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,267)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4.77 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">R&amp;D and orphan drug tax credits</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(5,642)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(29.74)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,321)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1.37)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,268)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4.78 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payment measurement</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">327</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.73</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">433 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.09 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,429 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5.01)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Mark-to-market adjustments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">919</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4.84</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,725 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.80 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,745)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5.47 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Transaction Costs</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">361</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.91</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.00 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.00 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest Expense</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,258)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(11.91)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,030 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.22 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.00 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Executive Compensation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">827</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4.36</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.00 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.00 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Accretion on preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.00</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.00 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(0.03)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation adjustments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.00</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(13,658)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2.95)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,688 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(14.16)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Mark-to-market investment in subsidiary</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.00</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.00 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(55)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.08 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income of partnerships not subject to tax</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.00</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.00 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(78)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.11 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Recognition of deferred tax assets not previously recognized</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.00</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,251)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1.35)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.00 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Current year losses for which no deferred tax asset is recognized</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">13,948</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">73.53</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,514 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.14 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,012 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(19.01)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">91</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.48</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(356)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(0.06)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">854 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1.25)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14,401</span></td><td colspan="2" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">75.92</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">112,409</span></td><td colspan="2" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">24.29 </span></td><td style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:0 1pt"/><td colspan="3" style="border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,221</span></td><td colspan="2" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3.25)</span></td><td style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div>The Company is also subject to taxation in the UK but to date no taxable income has been generated in the UK. Changes in corporate tax rates can change both the current tax expense (benefit) as well as the deferred tax expense (benefit). 3984000 0.2100 97183000 0.2100 -14372000 0.2100 1844000 0.0972 22111000 0.0478 -3267000 0.0477 5642000 0.2974 6321000 0.0137 3268000 -0.0478 327000 0.0173 433000 0.0009 3429000 -0.0501 919000 0.0484 3725000 0.0080 -3745000 0.0547 361000 0.0191 0 0.0000 0 0.0000 -2258000 -0.1191 1030000 0.0022 0 0.0000 827000 0.0436 0 0.0000 0 0.0000 0 0.0000 0 0.0000 22000 -0.0003 0 -0.0000 13658000 0.0295 -9688000 0.1416 0 -0.0000 0 -0.0000 55000 -0.0008 0 -0.0000 0 -0.0000 78000 -0.0011 0 -0.0000 6251000 0.0135 0 -0.0000 13948000 0.7353 14514000 0.0314 13012000 -0.1901 91000 0.0048 -356000 -0.0006 854000 -0.0125 14401000 0.7592 112409000 0.2429 2221000 -0.0325 <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets have been recognized in the U.S. jurisdiction in respect of the following items:</span></div><div style="margin-bottom:6pt"><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2019</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Operating tax losses</span></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">39,901</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">68,690 </span></td><td style="background-color:#ffffff;border-top:1pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Capital loss carryovers</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,292 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research credits</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">10,805</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,931 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payments</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,429</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,711 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">358</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,125 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Lease Liability</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">9,657</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,339 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other temporary differences</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,078</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,117 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets</span></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">68,228</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="background-color:#ffffff;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">104,205 </span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investment in subsidiaries</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(120,676)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(173,069)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">ROU asset</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(5,491)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,115)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fixed assets</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(3,588)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,225)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other temporary differences</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(27)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax liabilities</span></td><td colspan="2" style="border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(129,782)</span></td><td style="border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(182,409)</span></td><td style="background-color:#ffffff;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets (liabilities), net</span></td><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(61,554)</span></td><td style="background-color:#ffffff;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(78,204)</span></td><td style="background-color:#ffffff;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax liabilities, net, recognized</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">108,626</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">115,445 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div><table style="border-collapse:collapse;display:inline-table;vertical-align:top;width:96.716%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets, net, recognized</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(142)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets (liabilities), net, not recognized</span></td><td colspan="2" style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47,072</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="background-color:#ffffff;border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">37,099 </span></td><td style="border-bottom:1pt solid #183964;border-top:1pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table>We have recognized deferred tax assets related to entities in the U.S. Federal and Massachusetts consolidated return groups due to future reversals of existing taxable temporary differences that will be sufficient to recover the net deferred tax assets. Our remaining deferred tax assets have not been recognized because it is not probable that future taxable profits will be available to support their realizability. 39901000 68690000 0 2292000 10805000 9931000 5429000 9711000 358000 1125000 -9657000 -10339000 2078000 2117000 68228000 104205000 -120676000 -173069000 5491000 6115000 3588000 3225000 27000 0 129782000 182409000 -61554000 -78204000 108626000 115445000 0 -142000 47072000 37099000 -7400000 21800000 169700000 243000000.0 238100000 101900000 3900000 7400000 6700000 5200000 3700000 67400000 273000000.0 179500000 2100000 1600000 1300000 Sale of assets <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In February 2018, The Sync Project, Inc. (“Sync”) entered into an asset purchase agreement with Bose Corporation for the sale of certain assets and liabilities. The total aggregate purchase price was $4.5 million, consisting of approximately $4.0 million paid at closing and $0.5 million in cash deposited into escrow to be held for 12 months in order to secure the indemnification obligations of Sync after the closing date.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Health derecognized certain assets and liabilities based on their historical costs. The excess of the consideration transferred over the historical costs of the assets and liabilities resulted in a gain of approximately $4.0 million, which was recorded to the line item “Gain/(loss) on disposal of assets” on the accompanying Consolidated Statements Comprehensive Income/(Loss) for the year ended December 31, 2018.</span></div>Additionally, as part of the derecognition, the Company and certain preferred shareholders received a cash distribution of approximately $3.3 million during the year ended December 31, 2018. During the year ended December 31, 2019, certain preferred shareholders received further cash distributions of $0.1 million. As of December 31, 2020, no remaining third party obligations remained. 4500000 4000000.0 500000 4000000.0 3300000 100000 Tal Merger Agreement During the year ended December 31, 2018, Tal Medical, Inc. (“Tal”) a subsidiary of the Group entered into an option agreement with a third party, through which the third party was given the option to acquire substantially all of Tal’s assets. The option was contingent on the third party raising gross proceeds of $15.0 million prior to January 1, 2019 (the option expiration date). Upon the expiration of the option all external investors, not including PureTech, would be entitled to a distribution equal to the cash on hand on the date of expiration, and Tal’s operations would wind down. As of December 31, 2018, the minimum gross proceeds were not raised, resulting in the option expiring. As a result, the preferred shares were adjusted to the cash distribution the external investors were entitled to, which totaled $0.1 million, resulting in gain of $11.0 million being recognized in Finance income/(costs) – fair value accounting line of the Consolidated Statements of Comprehensive Income/(Loss) for the year ended December 31, 2018. In 2019 a merger was executed between PureTech and Tal wherein PureTech became the sole shareholder of Tal following the liquidation of all assets. In 2019, certain preferred shareholders received distributions of $0.1 million in connection with the merger. As of December 31, 2019 and 2020 Tal was an inactive entity in the Group’s Parent segment. 15000000.0 -100000 11000000.0 100000 Subsequent Events <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company has evaluated subsequent events after December 31, 2020, the date of issuance of the Consolidated Financial Statements, and has not identified any recordable or disclosable events not otherwise reported in these consolidated financial statements or notes thereto, except for the following:</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">OnJanuary 8, 2021, PureTech participated in the second closing of Vor’s Series B Preferred Share financing. For consideration of $0.5 million, PureTech received 961,538 shares.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On February 9, 2021, Vor closed its initial public offering of 9,828,017 shares at a price to the public of $18.00 per share. Subsequent to the closing, PureTech held 3,207,200 shares of Vor common stock, representing 8.6 percent of Vor common stock.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On February 9, 2021, PureTech Health sold 1,000,000 common shares of Karuna for aggregate proceeds of $118.0 million. Following the sale PureTech holds 2,406,564 shares of Karuna common stock, representing 8.2 percent of Karuna common stock.</span></div> 500000 961538 9828017 18.00 3207200 0.086 1000000 118000000.0 2406564 0.082