November 18, 2024 Bharatt Chowrira Chief Financial Officer PureTech Health plc 6 Tide Street, Suite 400 Boston, MA 02210 Re: PureTech Health plc Form 20-F for the fiscal year ended December 31, 2023 Filed April 25, 2024 File No. 001-39670 Dear Bharatt Chowrira: We have completed our review of your filing. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Charles Sherwood